| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemfibrozil_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSCAM | Down syndrome cell adhesion molecule | 0.116071 |
| MT2A | metallothionein 2A | 0.111127 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.103563 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.100722 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.099629 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0992996 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0978589 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0977551 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.092337 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0846035 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0803982 |
| GOLGA4 | golgin A4 | 0.0799917 |
| UBC | ubiquitin C | 0.0746746 |
| KRT17 | keratin 17, type I | 0.0724211 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0697455 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0694247 |
| EGFR | epidermal growth factor receptor | 0.0684902 |
| NDRG1 | N-myc downstream regulated 1 | 0.0682046 |
| FMNL2 | formin-like 2 | 0.0625085 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0589702 |
| SEPTIN9 | septin 9 | 0.0582556 |
| SMAD3 | SMAD family member 3 | 0.0558908 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0552892 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.055039 |
| TJP1 | tight junction protein 1 | 0.0546558 |
| HELZ | helicase with zinc finger | 0.0544854 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0535722 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0530065 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0524083 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0519877 |
| EZR | ezrin | 0.0515084 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0511107 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0508009 |
| SQSTM1 | sequestosome 1 | 0.0501752 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0493601 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.048269 |
| INTS6 | integrator complex subunit 6 | 0.0482682 |
| BRD2 | bromodomain containing 2 | 0.0482654 |
| NLGN1 | neuroligin 1 | 0.0475657 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0475644 |
| RPS3 | ribosomal protein S3 | 0.0469708 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.045978 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0459674 |
| RUNX1 | runt-related transcription factor 1 | 0.0455072 |
| ASPH | aspartate beta-hydroxylase | 0.0452526 |
| LAMA4 | laminin, alpha 4 | 0.0451095 |
| USP53 | ubiquitin specific peptidase 53 | 0.0450539 |
| FLNB | filamin B, beta | 0.0448412 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.044608 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0436928 |
| CALU | calumenin | 0.0428548 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0424251 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0416616 |
| SBF2 | SET binding factor 2 | 0.0415314 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0412988 |
| DSPP | dentin sialophosphoprotein | 0.0411452 |
| KYNU | kynureninase | 0.0409575 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0409019 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0408507 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0406448 |
| NF1 | neurofibromin 1 | 0.0405654 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0405146 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0402541 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0402363 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0399754 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0396004 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0393069 |
| NAV2 | neuron navigator 2 | 0.0392685 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0388541 |
| CDK6 | cyclin-dependent kinase 6 | 0.0388326 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0387642 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0385137 |
| PRKCA | protein kinase C, alpha | 0.0383611 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0378002 |
| RPS19 | ribosomal protein S19 | 0.0376262 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0372859 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0372126 |
| OXR1 | oxidation resistance 1 | 0.0371802 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0369133 |
| TBC1D5 | TBC1 domain family, member 5 | 0.036694 |
| FTL | ferritin, light polypeptide | 0.03656 |
| FHIT | fragile histidine triad | 0.0360619 |
| ATXN1 | ataxin 1 | 0.0360051 |
| MYOF | myoferlin | 0.0352698 |
| AHNAK | AHNAK nucleoprotein | 0.0347993 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0346247 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0344886 |
| RPS17 | ribosomal protein S17 | 0.0344374 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0343032 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0341966 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0341498 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0341296 |
| PTEN | phosphatase and tensin homolog | 0.0340073 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0339806 |
| RPL23 | ribosomal protein L23 | 0.0334022 |
| ANO6 | anoctamin 6 | 0.0333029 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0331453 |
| RPL12 | ribosomal protein L12 | 0.032846 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0326812 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0322049 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATOSA | atos homolog A | -0.135609 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0934151 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0873995 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0839766 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0700757 |
| GLIS3 | GLIS family zinc finger 3 | -0.0662746 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0652459 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0651489 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0601387 |
| INHBA | inhibin, beta A | -0.0582471 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0571239 |
| GRAMD2B | GRAM domain containing 2B | -0.0556697 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0554991 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0550457 |
| TXNIP | thioredoxin interacting protein | -0.0542064 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0540785 |
| ANXA2 | annexin A2 | -0.0538497 |
| SLMAP | sarcolemma associated protein | -0.0535685 |
| RBM47 | RNA binding motif protein 47 | -0.0515306 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0514831 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0514136 |
| TMSB10 | thymosin beta 10 | -0.0504607 |
| S100A9 | S100 calcium binding protein A9 | -0.0500948 |
| OSMR | oncostatin M receptor | -0.0498204 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0496257 |
| S100A8 | S100 calcium binding protein A8 | -0.0496087 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0491906 |
| RIOK3 | RIO kinase 3 | -0.0491836 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0489583 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0479153 |
| VCAN | versican | -0.0475512 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0475214 |
| RAB31 | RAB31, member RAS oncogene family | -0.0474379 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0472004 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0463761 |
| PRSS23 | protease, serine, 23 | -0.0460643 |
| ADNP | activity-dependent neuroprotector homeobox | -0.045795 |
| TMEM132D | transmembrane protein 132D | -0.0456485 |
| ABHD17C | abhydrolase domain containing 17C | -0.045037 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0449607 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0448457 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0446687 |
| KAZN | kazrin, periplakin interacting protein | -0.0445727 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0444851 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.044161 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0436778 |
| TMEM87A | transmembrane protein 87A | -0.0423428 |
| FOXO1 | forkhead box O1 | -0.042301 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | -0.0422898 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0420645 |
| CP | ceruloplasmin (ferroxidase) | -0.0416524 |
| CSNK1E | casein kinase 1, epsilon | -0.041566 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0411782 |
| FOXP1 | forkhead box P1 | -0.041064 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0408106 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0406866 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.0405882 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0401402 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0400519 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0390489 |
| MYO5C | myosin VC | -0.0389835 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0387399 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.03827 |
| THRB | thyroid hormone receptor, beta | -0.038031 |
| RAD51B | RAD51 paralog B | -0.0379323 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0378528 |
| CDKL5 | cyclin-dependent kinase-like 5 | -0.0378448 |
| CADM2 | cell adhesion molecule 2 | -0.037329 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0372679 |
| RC3H1 | ring finger and CCCH-type domains 1 | -0.0371273 |
| RPS25 | ribosomal protein S25 | -0.0371238 |
| USP15 | ubiquitin specific peptidase 15 | -0.0369754 |
| F11R | F11 receptor | -0.0369377 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0366039 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0362113 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0357719 |
| MUC16 | mucin 16, cell surface associated | -0.0354173 |
| COL1A2 | collagen, type I, alpha 2 | -0.0351726 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0351236 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | -0.035027 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0348443 |
| SERINC3 | serine incorporator 3 | -0.0347998 |
| CLDN7 | claudin 7 | -0.0346319 |
| GAK | cyclin G associated kinase | -0.0343969 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0341689 |
| WDR37 | WD repeat domain 37 | -0.0339847 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0339761 |
| SRPK1 | SRSF protein kinase 1 | -0.0339617 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | -0.0331657 |
| MTAP | methylthioadenosine phosphorylase | -0.0331573 |
| ZNF217 | zinc finger protein 217 | -0.0331153 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0331117 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0326315 |
| CDK13 | cyclin-dependent kinase 13 | -0.0322138 |
| KIF13B | kinesin family member 13B | -0.0322125 |
| SVIL | supervillin | -0.0316464 |
| LDLR | low density lipoprotein receptor | -0.0316234 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0315578 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0311345 |
| FN1 | fibronectin 1 | -0.0310094 |
