| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemfibrozil_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.182698 |
| FN1 | fibronectin 1 | 0.156121 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.13677 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.117118 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.115876 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.11484 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.109628 |
| ASPH | aspartate beta-hydroxylase | 0.108894 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.103604 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.103103 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0998891 |
| ATXN1 | ataxin 1 | 0.0983443 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0981284 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0895682 |
| LDHA | lactate dehydrogenase A | 0.0876341 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0831181 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0821665 |
| CALR | calreticulin | 0.0810519 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0781026 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0779799 |
| NDRG1 | N-myc downstream regulated 1 | 0.0775782 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.077277 |
| MYO1E | myosin IE | 0.0769616 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0763467 |
| FAT1 | FAT atypical cadherin 1 | 0.0747579 |
| GOLGB1 | golgin B1 | 0.0737028 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0706886 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0694256 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.065587 |
| CUX1 | cut-like homeobox 1 | 0.0644914 |
| CREB5 | cAMP responsive element binding protein 5 | 0.062357 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0623286 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0601537 |
| RBM39 | RNA binding motif protein 39 | 0.059391 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0591862 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0588852 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0584936 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0576751 |
| CERS6 | ceramide synthase 6 | 0.0574197 |
| PRELID2 | PRELI domain containing 2 | 0.0556423 |
| PTK2 | protein tyrosine kinase 2 | 0.0539217 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0535075 |
| RAB1A | RAB1A, member RAS oncogene family | 0.052899 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0524099 |
| INTS6 | integrator complex subunit 6 | 0.0518141 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0515181 |
| SPAG9 | sperm associated antigen 9 | 0.0509517 |
| JMJD1C | jumonji domain containing 1C | 0.0504878 |
| VMP1 | vacuole membrane protein 1 | 0.050017 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0492806 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0485871 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0485522 |
| LMO7 | LIM domain 7 | 0.0465275 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0461257 |
| SEPTIN9 | septin 9 | 0.0458368 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0454329 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0451121 |
| MCL1 | myeloid cell leukemia 1 | 0.0447558 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0447027 |
| CANX | calnexin | 0.0444652 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0441927 |
| ANXA2 | annexin A2 | 0.0430074 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0411767 |
| FMNL2 | formin-like 2 | 0.0410556 |
| ADIPOR2 | adiponectin receptor 2 | 0.0409586 |
| GPC6 | glypican 6 | 0.0409288 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0406341 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.040397 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.040343 |
| NAV2 | neuron navigator 2 | 0.0398106 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0394337 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0389806 |
| RAB10 | RAB10, member RAS oncogene family | 0.0389185 |
| UTRN | utrophin | 0.0381326 |
| COG5 | component of oligomeric golgi complex 5 | 0.0380965 |
| DST | dystonin | 0.0378992 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0377611 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.037589 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0360593 |
| APP | amyloid beta (A4) precursor protein | 0.0357485 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0350664 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0347562 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0334288 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.032742 |
| EPHA4 | EPH receptor A4 | 0.0327035 |
| COL5A2 | collagen, type V, alpha 2 | 0.0326936 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0307935 |
| ERBIN | erbb2 interacting protein | 0.0301675 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0297099 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0296666 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.029402 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0292841 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0290345 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0278705 |
| TOP1 | topoisomerase (DNA) I | 0.0278121 |
| SBF2 | SET binding factor 2 | 0.027733 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0272421 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.027082 |
| NF1 | neurofibromin 1 | 0.0267408 |
| FNIP1 | folliculin interacting protein 1 | 0.0264581 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INHBA | inhibin, beta A | -0.131875 |
| TMSB10 | thymosin beta 10 | -0.119274 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.109411 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.100503 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0973465 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0971751 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0909033 |
| STC1 | stanniocalcin 1 | -0.0869454 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0866981 |
| EFNA5 | ephrin-A5 | -0.0819303 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0813847 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0801331 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0783956 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0771953 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0766791 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0765775 |
| PKM | pyruvate kinase, muscle | -0.0714038 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0709486 |
| GLIS3 | GLIS family zinc finger 3 | -0.0701726 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0677947 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0668603 |
| OSMR | oncostatin M receptor | -0.066613 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0654534 |
| PYGL | phosphorylase, glycogen, liver | -0.0644927 |
| VCL | vinculin | -0.0634785 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0616954 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0614823 |
| RPL35A | ribosomal protein L35a | -0.0598689 |
| CDKL5 | cyclin-dependent kinase-like 5 | -0.0595994 |
| DOCK5 | dedicator of cytokinesis 5 | -0.059147 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0591263 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0585129 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0579689 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0571749 |
| EMP1 | epithelial membrane protein 1 | -0.0562006 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0553827 |
| ZNF292 | zinc finger protein 292 | -0.0552798 |
| MMP1 | matrix metallopeptidase 1 | -0.054505 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0531241 |
| RAI14 | retinoic acid induced 14 | -0.0524263 |
| DTNA | dystrobrevin, alpha | -0.0520846 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0520669 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0512321 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0507064 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0501142 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0500473 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0499572 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0486688 |
| ACTN1 | actinin, alpha 1 | -0.0481281 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0478274 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0471909 |
| RPS6 | ribosomal protein S6 | -0.046952 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0465885 |
| ATP9B | ATPase, class II, type 9B | -0.0464171 |
| JAK1 | Janus kinase 1 | -0.0463007 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0452741 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0438877 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0435778 |
| AOPEP | aminopeptidase O (putative) | -0.0433211 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0431282 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0425256 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0424431 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0415229 |
| FLNB | filamin B, beta | -0.041435 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0412115 |
| ANO6 | anoctamin 6 | -0.0411623 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0406512 |
| NRXN3 | neurexin 3 | -0.0394004 |
| NAV1 | neuron navigator 1 | -0.0388337 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0381584 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0377266 |
| RTN4 | reticulon 4 | -0.0377063 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0375213 |
| S100A10 | S100 calcium binding protein A10 | -0.0371342 |
| MEIS2 | Meis homeobox 2 | -0.036332 |
| RPL5 | ribosomal protein L5 | -0.0360992 |
| OGA | O-GlcNAcase | -0.0360849 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.0359501 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0359085 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0357339 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0349726 |
| RPL23 | ribosomal protein L23 | -0.0348499 |
| TCF12 | transcription factor 12 | -0.0347868 |
| GPHN | gephyrin | -0.0345307 |
| RPS8 | ribosomal protein S8 | -0.0344056 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0340071 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | -0.033935 |
| FOXP1 | forkhead box P1 | -0.033707 |
| DENND1A | DENN/MADD domain containing 1A | -0.0336813 |
| VIM | vimentin | -0.0335308 |
| H3-3B | H3.3 histone B | -0.0333834 |
| TMEM165 | transmembrane protein 165 | -0.0333802 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0331245 |
| RPLP1 | ribosomal protein, large, P1 | -0.0331044 |
| PDLIM5 | PDZ and LIM domain 5 | -0.033094 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.033014 |
| RPL37 | ribosomal protein L37 | -0.0328551 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.032813 |
| HDAC4 | histone deacetylase 4 | -0.0323482 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0323397 |
