| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gemfibrozil_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.140637 |
| COL11A1 | collagen, type XI, alpha 1 | 0.137212 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.127597 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.107287 |
| DST | dystonin | 0.100203 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0820713 |
| COL5A2 | collagen, type V, alpha 2 | 0.0810478 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0796629 |
| HDAC9 | histone deacetylase 9 | 0.0779146 |
| ANK2 | ankyrin 2, neuronal | 0.0754776 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0722386 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.065055 |
| TENM3 | teneurin transmembrane protein 3 | 0.0642197 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0638492 |
| CDH19 | cadherin 19, type 2 | 0.0613896 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0562404 |
| NTM | neurotrimin | 0.0547877 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0538246 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0521726 |
| MKI67 | marker of proliferation Ki-67 | 0.051682 |
| FOXP2 | forkhead box P2 | 0.0511311 |
| NFIA | nuclear factor I/A | 0.0497432 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0495663 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0483948 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0476656 |
| RDX | radixin | 0.0467661 |
| PDGFC | platelet derived growth factor C | 0.0467436 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0461296 |
| NHSL1 | NHS-like 1 | 0.0459971 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0452158 |
| UTRN | utrophin | 0.0440231 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.043764 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0430663 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.042732 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0416993 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0409556 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0406748 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.040249 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.039311 |
| TOX | thymocyte selection-associated high mobility group box | 0.0390359 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.038042 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0374372 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0371926 |
| USP53 | ubiquitin specific peptidase 53 | 0.0371528 |
| CADM2 | cell adhesion molecule 2 | 0.0371144 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0370137 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0367218 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0366449 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0362797 |
| PRELID2 | PRELI domain containing 2 | 0.0360753 |
| ZNF292 | zinc finger protein 292 | 0.0355974 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0351736 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0350156 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0350073 |
| ZNF608 | zinc finger protein 608 | 0.0349953 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0346808 |
| TAOK1 | TAO kinase 1 | 0.0343414 |
| SMYD3 | SET and MYND domain containing 3 | 0.0339111 |
| ABI2 | abl-interactor 2 | 0.0336761 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0334647 |
| TNRC6B | trinucleotide repeat containing 6B | 0.032983 |
| PHF21A | PHD finger protein 21A | 0.0322403 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0322129 |
| SBF2 | SET binding factor 2 | 0.0319174 |
| CENPE | centromere protein E, 312kDa | 0.0314634 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0310991 |
| DUSP6 | dual specificity phosphatase 6 | 0.0310096 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0309443 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0305176 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0303941 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.030231 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0301329 |
| RBM33 | RNA binding motif protein 33 | 0.0300455 |
| VMP1 | vacuole membrane protein 1 | 0.0297442 |
| JMJD1C | jumonji domain containing 1C | 0.0296436 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0295052 |
| TJP1 | tight junction protein 1 | 0.0294917 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0292052 |
| MED13 | mediator complex subunit 13 | 0.0291566 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.029118 |
| SP3 | Sp3 transcription factor | 0.0290721 |
| DEK | DEK proto-oncogene | 0.0285337 |
| WDR70 | WD repeat domain 70 | 0.0284285 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.028277 |
| TPM3 | tropomyosin 3 | 0.0282127 |
| ANKRD12 | ankyrin repeat domain 12 | 0.028034 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0276438 |
| RASAL2 | RAS protein activator like 2 | 0.0276171 |
| HDAC2 | histone deacetylase 2 | 0.0275937 |
| CDK6 | cyclin-dependent kinase 6 | 0.0275696 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0273676 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0272988 |
| LIN28B | lin-28 homolog B (C. elegans) | 0.0272539 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0272112 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0269367 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0268134 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0267992 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.026783 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0265527 |
| GPC4 | glypican 4 | 0.0263783 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.167991 |
| RPS16 | ribosomal protein S16 | -0.13045 |
| RPS6 | ribosomal protein S6 | -0.104967 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.096384 |
| TMSB10 | thymosin beta 10 | -0.0844383 |
| RPL35A | ribosomal protein L35a | -0.0781536 |
| RPS8 | ribosomal protein S8 | -0.0759308 |
| VIM | vimentin | -0.067157 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0655121 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0649512 |
| COL1A2 | collagen, type I, alpha 2 | -0.064412 |
| RPS12 | ribosomal protein S12 | -0.0605472 |
| RPL37 | ribosomal protein L37 | -0.0593554 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0574807 |
| B2M | beta-2-microglobulin | -0.056066 |
| RPL34 | ribosomal protein L34 | -0.0546391 |
| PGK1 | phosphoglycerate kinase 1 | -0.0530602 |
| RPL11 | ribosomal protein L11 | -0.0513068 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0486487 |
| RPS25 | ribosomal protein S25 | -0.0475464 |
| RPL31 | ribosomal protein L31 | -0.0473351 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0450626 |
| CAVIN1 | caveolae associated protein 1 | -0.0449772 |
| RIGI | RNA sensor RIG-I | -0.0437231 |
| RPS13 | ribosomal protein S13 | -0.0431547 |
| RPL37A | ribosomal protein L37a | -0.0424174 |
| RPL9 | ribosomal protein L9 | -0.0413271 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0406848 |
| RPL23 | ribosomal protein L23 | -0.039254 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0379974 |
| NUP160 | nucleoporin 160kDa | -0.0377465 |
| SPAG9 | sperm associated antigen 9 | -0.0372172 |
| RPS29 | ribosomal protein S29 | -0.0367051 |
| RPS19 | ribosomal protein S19 | -0.0363627 |
| RPS24 | ribosomal protein S24 | -0.0363341 |
| GNAS | GNAS complex locus | -0.03621 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0351624 |
| FTL | ferritin, light polypeptide | -0.0345544 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0339115 |
| RPLP1 | ribosomal protein, large, P1 | -0.0338365 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0330528 |
| RPL12 | ribosomal protein L12 | -0.0325306 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0322563 |
| RACK1 | receptor for activated C kinase 1 | -0.0316016 |
| APOE | apolipoprotein E | -0.0312361 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0311674 |
| RPS10 | ribosomal protein S10 | -0.0307506 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0299682 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0293027 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0288392 |
| RPL7A | ribosomal protein L7a | -0.0286151 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0285393 |
| RPS17 | ribosomal protein S17 | -0.0283568 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0282381 |
| RPLP0 | ribosomal protein, large, P0 | -0.0276405 |
| S100A10 | S100 calcium binding protein A10 | -0.0273812 |
| RPS15 | ribosomal protein S15 | -0.0267282 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0266474 |
| FBL | fibrillarin | -0.0261891 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0260561 |
| RPS23 | ribosomal protein S23 | -0.0260298 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0256213 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0255294 |
| KIAA1958 | KIAA1958 | -0.0254085 |
| TBCA | tubulin folding cofactor A | -0.0253697 |
| MYADM | myeloid-associated differentiation marker | -0.0253581 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0252786 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.025186 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0251537 |
| PKM | pyruvate kinase, muscle | -0.0250779 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0249309 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0248282 |
| RPS21 | ribosomal protein S21 | -0.0247561 |
| FGF13 | fibroblast growth factor 13 | -0.0244199 |
| S100A9 | S100 calcium binding protein A9 | -0.0244036 |
| RPL19 | ribosomal protein L19 | -0.0244034 |
| DSTN | destrin (actin depolymerizing factor) | -0.0242751 |
| NXN | nucleoredoxin | -0.0240875 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0240261 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0237654 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0237199 |
| FBXO27 | F-box protein 27 | -0.0237181 |
| UBN2 | ubinuclein 2 | -0.0235298 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0234765 |
| LATS2 | large tumor suppressor kinase 2 | -0.0234027 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | -0.0228923 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0228624 |
| IP6K1 | inositol hexakisphosphate kinase 1 | -0.0226764 |
| RPL36A | ribosomal protein L36a | -0.0225324 |
| MAP4 | microtubule-associated protein 4 | -0.02249 |
| ENAH | enabled homolog (Drosophila) | -0.0223491 |
| IGF1R | insulin-like growth factor 1 receptor | -0.022315 |
| LYST | lysosomal trafficking regulator | -0.0222087 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0220022 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0218985 |
| SNX6 | sorting nexin 6 | -0.0217307 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0217121 |
| ANXA2 | annexin A2 | -0.0216262 |
| HM13 | histocompatibility (minor) 13 | -0.0213318 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | -0.02105 |
