| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gemfibrozil_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.249162 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.156039 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.120055 |
| LDHA | lactate dehydrogenase A | 0.083574 |
| IER3 | immediate early response 3 | 0.0787581 |
| ASPH | aspartate beta-hydroxylase | 0.07735 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0738176 |
| SQSTM1 | sequestosome 1 | 0.0725193 |
| PRELID2 | PRELI domain containing 2 | 0.0717557 |
| HDAC9 | histone deacetylase 9 | 0.0698121 |
| VEGFA | vascular endothelial growth factor A | 0.0671264 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0669298 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0665739 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0655685 |
| INTS6 | integrator complex subunit 6 | 0.0653026 |
| MYOF | myoferlin | 0.0633641 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0620219 |
| CDH13 | cadherin 13 | 0.0609578 |
| SEPTIN9 | septin 9 | 0.0595219 |
| HMGA2 | high mobility group AT-hook 2 | 0.0563078 |
| RAD51B | RAD51 paralog B | 0.0561299 |
| FNIP1 | folliculin interacting protein 1 | 0.0545144 |
| ATXN1 | ataxin 1 | 0.0537285 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0534023 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0528301 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0497229 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0493591 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0490404 |
| NDRG1 | N-myc downstream regulated 1 | 0.0482729 |
| DUSP10 | dual specificity phosphatase 10 | 0.0464739 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.046434 |
| EFNA5 | ephrin-A5 | 0.0458354 |
| NAV2 | neuron navigator 2 | 0.044321 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0442076 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0439287 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0433701 |
| PDE10A | phosphodiesterase 10A | 0.0431054 |
| CADM1 | cell adhesion molecule 1 | 0.0429756 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0429695 |
| STC1 | stanniocalcin 1 | 0.0419572 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0404807 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0404753 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0398616 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0384909 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0376811 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0376431 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0365466 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0361026 |
| EGFR | epidermal growth factor receptor | 0.036009 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0348765 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0340737 |
| COL5A1 | collagen, type V, alpha 1 | 0.0339671 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0339452 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.033517 |
| CUL4B | cullin 4B | 0.0333868 |
| TMEM132D | transmembrane protein 132D | 0.0329504 |
| BRD2 | bromodomain containing 2 | 0.032931 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0327101 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0326978 |
| GOLGB1 | golgin B1 | 0.0326813 |
| WWOX | WW domain containing oxidoreductase | 0.0326407 |
| DTNA | dystrobrevin, alpha | 0.0325826 |
| FMNL2 | formin-like 2 | 0.032249 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0321994 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0321817 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0320969 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0318613 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0316011 |
| MYO10 | myosin X | 0.0299632 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0299085 |
| FBXO32 | F-box protein 32 | 0.0296705 |
| TRAM2 | translocation associated membrane protein 2 | 0.029604 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.029392 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0281991 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0280015 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0279603 |
| PCBP3 | poly(rC) binding protein 3 | 0.027901 |
| SFTPA2 | surfactant protein A2 | 0.02781 |
| CALR | calreticulin | 0.0277792 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0275612 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0269397 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0268936 |
| INHBA | inhibin, beta A | 0.0268738 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0268695 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0267586 |
| PRKCA | protein kinase C, alpha | 0.0266308 |
| BBX | bobby sox homolog (Drosophila) | 0.0266072 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0263135 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0260848 |
| BNC2 | basonuclin 2 | 0.0260475 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0259105 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0258017 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0255887 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0255174 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.02549 |
| PRKCE | protein kinase C, epsilon | 0.0254593 |
| FHIT | fragile histidine triad | 0.0253684 |
| EXOC4 | exocyst complex component 4 | 0.0252578 |
| RND3 | Rho family GTPase 3 | 0.0251807 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0251195 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.174199 |
| VIM | vimentin | -0.13277 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.120614 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116036 |
| BICC1 | BicC family RNA binding protein 1 | -0.111555 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.105379 |
| TMSB10 | thymosin beta 10 | -0.103301 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0930992 |
| VCL | vinculin | -0.088847 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.087805 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0856637 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0737125 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0729227 |
| ANXA2 | annexin A2 | -0.0719857 |
| HLA-B | major histocompatibility complex, class I, B | -0.0708383 |
| MT2A | metallothionein 2A | -0.0695321 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0662147 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0651198 |
| RPL23 | ribosomal protein L23 | -0.0628699 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0627374 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0619345 |
| PTMA | prothymosin, alpha | -0.0611083 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0604283 |
| THBS1 | thrombospondin 1 | -0.0592561 |
| AHNAK | AHNAK nucleoprotein | -0.0589325 |
| UBC | ubiquitin C | -0.0541189 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0527823 |
| RPS27A | ribosomal protein S27a | -0.0520438 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0506832 |
| FN1 | fibronectin 1 | -0.0487759 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0458416 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0429218 |
| RTN4 | reticulon 4 | -0.0417651 |
| RPLP2 | ribosomal protein, large, P2 | -0.0412939 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0412696 |
| RPL19 | ribosomal protein L19 | -0.0409979 |
| LOC112694756 | uncharaterized LOC112694756 | -0.040803 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0407132 |
| MKI67 | marker of proliferation Ki-67 | -0.0402234 |
| RPL36A | ribosomal protein L36a | -0.0398922 |
| RPLP1 | ribosomal protein, large, P1 | -0.037938 |
| PALLD | palladin, cytoskeletal associated protein | -0.0379238 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0371712 |
| SMAD3 | SMAD family member 3 | -0.0371396 |
| RPS6 | ribosomal protein S6 | -0.0367558 |
| RPL35A | ribosomal protein L35a | -0.0350559 |
| CDCP1 | CUB domain containing protein 1 | -0.0347255 |
| RPL36 | ribosomal protein L36 | -0.0346872 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0343761 |
| TPM4 | tropomyosin 4 | -0.0343374 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0341208 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0340433 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.033856 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0336609 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0333754 |
| RPL12 | ribosomal protein L12 | -0.0326643 |
| CDK17 | cyclin-dependent kinase 17 | -0.032522 |
| ATP13A3 | ATPase type 13A3 | -0.0323821 |
| PCBP2 | poly(rC) binding protein 2 | -0.0318798 |
| RPS23 | ribosomal protein S23 | -0.0318044 |
| TXNRD1 | thioredoxin reductase 1 | -0.0317166 |
| RPS19 | ribosomal protein S19 | -0.0316264 |
| RPS21 | ribosomal protein S21 | -0.031554 |
| OSMR | oncostatin M receptor | -0.0312745 |
| DENND5A | DENN/MADD domain containing 5A | -0.0309748 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0304052 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.030192 |
| RPS13 | ribosomal protein S13 | -0.03017 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0300158 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0298567 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0297519 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0297391 |
| TMEM41B | transmembrane protein 41B | -0.0297323 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0285749 |
| SBF2 | SET binding factor 2 | -0.0281847 |
| SERINC1 | serine incorporator 1 | -0.0281163 |
| TNNC1 | troponin C type 1 (slow) | -0.0274969 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0262699 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0259145 |
| RPL26 | ribosomal protein L26 | -0.0257961 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0256661 |
| ASTN2 | astrotactin 2 | -0.025367 |
| CD99 | CD99 molecule | -0.0250918 |
| RPL8 | ribosomal protein L8 | -0.025017 |
| EGR1 | early growth response 1 | -0.0247574 |
| FTL | ferritin, light polypeptide | -0.0245079 |
| IL6 | interleukin 6 | -0.0242183 |
| MAP4 | microtubule-associated protein 4 | -0.0241649 |
| RPL15 | ribosomal protein L15 | -0.024164 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0240976 |
| RAI14 | retinoic acid induced 14 | -0.0239768 |
| WTAP | Wilms tumor 1 associated protein | -0.0238648 |
| HLA-C | major histocompatibility complex, class I, C | -0.0238237 |
| AFDN | afadin, adherens junction formation factor | -0.0236493 |
| MX1 | MX dynamin-like GTPase 1 | -0.0236365 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.02355 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.0234297 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0233245 |
| CALD1 | caldesmon 1 | -0.0232464 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.022809 |
