| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemfibrozil_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.105988 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0981325 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0819875 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0807552 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0780509 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0772005 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0750554 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0749281 |
| KYNU | kynureninase | 0.0707012 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0702422 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0686154 |
| CD44 | CD44 molecule (Indian blood group) | 0.0644542 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.063597 |
| UBC | ubiquitin C | 0.0616564 |
| LDHA | lactate dehydrogenase A | 0.0611901 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0542664 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0538442 |
| STC1 | stanniocalcin 1 | 0.0534912 |
| SEPTIN7 | septin 7 | 0.0533305 |
| MSN | moesin | 0.0487548 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0478218 |
| RND3 | Rho family GTPase 3 | 0.0471241 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.046027 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0459592 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0457802 |
| SPAG9 | sperm associated antigen 9 | 0.0457394 |
| RTN4 | reticulon 4 | 0.0457384 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0454629 |
| SMAD3 | SMAD family member 3 | 0.044825 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0447728 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0443682 |
| ARRDC3 | arrestin domain containing 3 | 0.0440666 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0440299 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0430433 |
| NAV1 | neuron navigator 1 | 0.0430063 |
| EGFR | epidermal growth factor receptor | 0.0427594 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0413658 |
| POTEF | POTE ankyrin domain family, member F | 0.0412721 |
| ENO1 | enolase 1, (alpha) | 0.0407921 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0406636 |
| CALD1 | caldesmon 1 | 0.0406074 |
| SET | SET nuclear proto-oncogene | 0.0391602 |
| IL6ST | interleukin 6 signal transducer | 0.0389687 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0388032 |
| DST | dystonin | 0.0385141 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0384716 |
| RNF24 | ring finger protein 24 | 0.0383485 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0379025 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0378186 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0376183 |
| PKM | pyruvate kinase, muscle | 0.0373763 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0371377 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.036944 |
| VCL | vinculin | 0.0369308 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0366592 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0365804 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0362097 |
| RNF145 | ring finger protein 145 | 0.0361067 |
| ANLN | anillin, actin binding protein | 0.0360297 |
| CALU | calumenin | 0.035791 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0355344 |
| TPM3 | tropomyosin 3 | 0.0349994 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0348489 |
| PTK2 | protein tyrosine kinase 2 | 0.0347928 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0342178 |
| TLN1 | talin 1 | 0.0341971 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.034151 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0339579 |
| CDK6 | cyclin-dependent kinase 6 | 0.0338195 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0335544 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0324719 |
| COL1A1 | collagen, type I, alpha 1 | 0.0323599 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0323203 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0322378 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0321998 |
| GSE1 | Gse1 coiled-coil protein | 0.0317811 |
| CALR | calreticulin | 0.0317306 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0316264 |
| COL6A3 | collagen, type VI, alpha 3 | 0.031517 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0315047 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0314403 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0314263 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0314125 |
| TXNIP | thioredoxin interacting protein | 0.0313914 |
| VEGFC | vascular endothelial growth factor C | 0.0313863 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0313015 |
| FAT1 | FAT atypical cadherin 1 | 0.0312452 |
| RBM25 | RNA binding motif protein 25 | 0.0311901 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0311883 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0311151 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0309132 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0306299 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0305259 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0299405 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0296025 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0292381 |
| VMP1 | vacuole membrane protein 1 | 0.0292328 |
| TNPO3 | transportin 3 | 0.0291909 |
| MYOF | myoferlin | 0.0290352 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0290089 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.157645 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130116 |
| TMSB10 | thymosin beta 10 | -0.088777 |
| FN1 | fibronectin 1 | -0.0723291 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0669047 |
| HLA-C | major histocompatibility complex, class I, C | -0.062642 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0591613 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0554431 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0546947 |
| FTL | ferritin, light polypeptide | -0.0545476 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.053208 |
| COL6A1 | collagen, type VI, alpha 1 | -0.051398 |
| AHNAK | AHNAK nucleoprotein | -0.0508357 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0502884 |
| VIM | vimentin | -0.0481287 |
| CDH13 | cadherin 13 | -0.0456753 |
| PGK1 | phosphoglycerate kinase 1 | -0.0454543 |
| LOX | lysyl oxidase | -0.0452983 |
| HLA-A | major histocompatibility complex, class I, A | -0.0433188 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0432571 |
| GNAS | GNAS complex locus | -0.0431399 |
| RAD51B | RAD51 paralog B | -0.0411661 |
| HM13 | histocompatibility (minor) 13 | -0.0407864 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0396835 |
| RAI14 | retinoic acid induced 14 | -0.0391617 |
| RPL34 | ribosomal protein L34 | -0.0383436 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0378249 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0370469 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0370424 |
| VDAC1 | voltage-dependent anion channel 1 | -0.035338 |
| S100A6 | S100 calcium binding protein A6 | -0.0351269 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0344241 |
| TPM4 | tropomyosin 4 | -0.0343182 |
| HDLBP | high density lipoprotein binding protein | -0.0336444 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0331747 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0317186 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0316584 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0316047 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0312142 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0299701 |
| RPLP1 | ribosomal protein, large, P1 | -0.0295417 |
| RPS23 | ribosomal protein S23 | -0.0294042 |
| RPS16 | ribosomal protein S16 | -0.0290627 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0287205 |
| COG6 | component of oligomeric golgi complex 6 | -0.0281341 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0278941 |
| CAVIN1 | caveolae associated protein 1 | -0.0277897 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0276588 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0274069 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0270436 |
| XPO1 | exportin 1 | -0.0257508 |
| RPS29 | ribosomal protein S29 | -0.0256138 |
| C1R | complement component 1, r subcomponent | -0.025499 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0254516 |
| RPL31 | ribosomal protein L31 | -0.0253761 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.025336 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0250078 |
| RPL35A | ribosomal protein L35a | -0.0249929 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0248118 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.024657 |
| SMYD3 | SET and MYND domain containing 3 | -0.024267 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.024253 |
| TNPO1 | transportin 1 | -0.0242311 |
| RPS21 | ribosomal protein S21 | -0.024222 |
| RPL36 | ribosomal protein L36 | -0.0241255 |
| RBM6 | RNA binding motif protein 6 | -0.0240977 |
| RPS11 | ribosomal protein S11 | -0.0240074 |
| EFHD2 | EF-hand domain family, member D2 | -0.0233719 |
| EGR1 | early growth response 1 | -0.0233424 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0232519 |
| RPS14 | ribosomal protein S14 | -0.0231264 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0228496 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0225774 |
| PYGL | phosphorylase, glycogen, liver | -0.0225773 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0223857 |
| COL5A2 | collagen, type V, alpha 2 | -0.0222181 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0221832 |
| FAM3C | family with sequence similarity 3, member C | -0.0220956 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0220529 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.021972 |
| YME1L1 | YME1-like 1 ATPase | -0.0219137 |
| GPR173 | G protein-coupled receptor 173 | -0.0217285 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0216521 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0215416 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0215025 |
| GPX8 | glutathione peroxidase 8 (putative) | -0.0213537 |
| YY1 | YY1 transcription factor | -0.0213062 |
| LMAN2 | lectin, mannose-binding 2 | -0.0212613 |
| TUBA1B | tubulin, alpha 1b | -0.0212221 |
| RPL23 | ribosomal protein L23 | -0.0210003 |
| CA9 | carbonic anhydrase IX | -0.0208878 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0207407 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0207259 |
| ANKRD33B | ankyrin repeat domain 33B | -0.020657 |
| CADM1 | cell adhesion molecule 1 | -0.0206026 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0205973 |
| RPL37 | ribosomal protein L37 | -0.0205372 |
| HIRA | histone cell cycle regulator | -0.0205316 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0202904 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.0202178 |
