| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemfibrozil_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.144155 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.136698 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.109303 |
| HMGA2 | high mobility group AT-hook 2 | 0.107004 |
| INTS6 | integrator complex subunit 6 | 0.103402 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0986764 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.098077 |
| SLC38A2 | solute carrier family 38, member 2 | 0.094097 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0882027 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0878057 |
| POTEF | POTE ankyrin domain family, member F | 0.0860526 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0852178 |
| FMNL2 | formin-like 2 | 0.0746989 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0718391 |
| ENO1 | enolase 1, (alpha) | 0.0707742 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0695549 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.066296 |
| EGFR | epidermal growth factor receptor | 0.0661021 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0651004 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0612044 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0606619 |
| LMO7 | LIM domain 7 | 0.0601335 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0595208 |
| DST | dystonin | 0.0594799 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.059184 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0571747 |
| CD44 | CD44 molecule (Indian blood group) | 0.0557736 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0551456 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.054885 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0485556 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0485181 |
| SQSTM1 | sequestosome 1 | 0.0484363 |
| PKM | pyruvate kinase, muscle | 0.0476218 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0475086 |
| ANGPTL4 | angiopoietin-like 4 | 0.0474432 |
| ATXN1 | ataxin 1 | 0.0470177 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0469628 |
| JAK1 | Janus kinase 1 | 0.0467296 |
| RUNX1 | runt-related transcription factor 1 | 0.0445907 |
| SVIL | supervillin | 0.0444085 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0440791 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0428983 |
| RTN4 | reticulon 4 | 0.0423726 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0421169 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0419631 |
| TOP1 | topoisomerase (DNA) I | 0.0417527 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0412414 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0401096 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0400511 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0399658 |
| ERBIN | erbb2 interacting protein | 0.0399548 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0398572 |
| ZNF638 | zinc finger protein 638 | 0.039769 |
| ANXA1 | annexin A1 | 0.0392402 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.038365 |
| FRMD6 | FERM domain containing 6 | 0.0382092 |
| RIGI | RNA sensor RIG-I | 0.0376964 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0375756 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0374027 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0371658 |
| UTRN | utrophin | 0.0369009 |
| DTNA | dystrobrevin, alpha | 0.0365388 |
| RASAL2 | RAS protein activator like 2 | 0.0360774 |
| CLIC4 | chloride intracellular channel 4 | 0.0359487 |
| AHNAK | AHNAK nucleoprotein | 0.0354934 |
| TRIM44 | tripartite motif containing 44 | 0.0347928 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0347674 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.034518 |
| NLK | nemo-like kinase | 0.0344605 |
| BBX | bobby sox homolog (Drosophila) | 0.0342096 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0340643 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0337003 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0332875 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0330853 |
| USP3 | ubiquitin specific peptidase 3 | 0.0328617 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0327102 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0324933 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0324704 |
| IL6ST | interleukin 6 signal transducer | 0.0324363 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0323445 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0322359 |
| SHPRH | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | 0.0319033 |
| TRAM2 | translocation associated membrane protein 2 | 0.0317265 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0317224 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.031686 |
| ASPH | aspartate beta-hydroxylase | 0.0313779 |
| SMAD3 | SMAD family member 3 | 0.0313052 |
| ITGA6 | integrin, alpha 6 | 0.0311462 |
| ACTN1 | actinin, alpha 1 | 0.0311428 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0310108 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0309324 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0306315 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0303567 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0302601 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0302395 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0301089 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0300498 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0299799 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0298585 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0296001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0864796 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0701433 |
| OSMR | oncostatin M receptor | -0.0652934 |
| PTMA | prothymosin, alpha | -0.0569028 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0517692 |
| RPL35A | ribosomal protein L35a | -0.0511835 |
| DNER | delta/notch-like EGF repeat containing | -0.0494587 |
| MATR3 | matrin 3 | -0.0486232 |
| ZNF292 | zinc finger protein 292 | -0.0477136 |
| SMYD3 | SET and MYND domain containing 3 | -0.0471134 |
| RBM39 | RNA binding motif protein 39 | -0.0465326 |
| LOC112694756 | uncharaterized LOC112694756 | -0.046237 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0438845 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0438167 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0411553 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0406394 |
| TCERG1 | transcription elongation regulator 1 | -0.0405573 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0400861 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0396064 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0392512 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0386786 |
| ACER3 | alkaline ceramidase 3 | -0.0380397 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0378438 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0377791 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0366797 |
| KIAA1328 | KIAA1328 | -0.0366353 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0359537 |
| CEP290 | centrosomal protein 290kDa | -0.0358923 |
| RPL30 | ribosomal protein L30 | -0.0358074 |
| FAF2 | Fas associated factor family member 2 | -0.0354674 |
| HLA-C | major histocompatibility complex, class I, C | -0.0353005 |
| RPL34 | ribosomal protein L34 | -0.0341577 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0340642 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0339043 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.0337703 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0332435 |
| XPO1 | exportin 1 | -0.0332386 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0330855 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0329669 |
| TPM4 | tropomyosin 4 | -0.0325843 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0324175 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0323148 |
| RBM25 | RNA binding motif protein 25 | -0.0321972 |
| CENPF | centromere protein F, 350/400kDa | -0.0321763 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0321109 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0319027 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0317672 |
| RPL23 | ribosomal protein L23 | -0.0316572 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0316522 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0311402 |
| PHF3 | PHD finger protein 3 | -0.0311392 |
| BSG | basigin (Ok blood group) | -0.0309971 |
| RPS27A | ribosomal protein S27a | -0.030925 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0307534 |
| CEP95 | centrosomal protein 95kDa | -0.030663 |
| NOP58 | NOP58 ribonucleoprotein | -0.030372 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0302715 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0294992 |
| FAM193A | family with sequence similarity 193, member A | -0.0293233 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0292767 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0287377 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0285658 |
| NALCN | sodium leak channel, non selective | -0.0283527 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0282915 |
| RPL37 | ribosomal protein L37 | -0.0275997 |
| RPL12 | ribosomal protein L12 | -0.0273151 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0270946 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0268654 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0267317 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0263394 |
| CDK5RAP1 | CDK5 regulatory subunit associated protein 1 | -0.0263386 |
| RPS20 | ribosomal protein S20 | -0.0262514 |
| RPLP1 | ribosomal protein, large, P1 | -0.0262125 |
| SEPTIN2 | septin 2 | -0.0261788 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0260893 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0260311 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0259005 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0258204 |
| HJURP | Holliday junction recognition protein | -0.0256372 |
| YARS1 | tyrosyl-tRNA synthetase 1 | -0.0256051 |
| VIM | vimentin | -0.0254654 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0254543 |
| RPL4 | ribosomal protein L4 | -0.0253118 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0252555 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0251944 |
| GLCCI1 | glucocorticoid induced 1 | -0.0251398 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.025109 |
| RPL31 | ribosomal protein L31 | -0.0249848 |
| KIAA1958 | KIAA1958 | -0.0249308 |
| RPL35 | ribosomal protein L35 | -0.0248794 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0248572 |
| ELP2 | elongator acetyltransferase complex subunit 2 | -0.0248159 |
| SETD5 | SET domain containing 5 | -0.0247947 |
| CEP57L1 | centrosomal protein 57kDa-like 1 | -0.0246367 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0244708 |
| HDLBP | high density lipoprotein binding protein | -0.0243806 |
| REST | RE1-silencing transcription factor | -0.0243709 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.0243037 |
| PRKD1 | protein kinase D1 | -0.0241762 |
| NUP98 | nucleoporin 98kDa | -0.0241043 |
