Generalized seizures_Brain_GSE6614 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE6614
Similar Terms
Downloads & Tools

Genes

600 genes differentially expressed during Generalized seizures_Brain_GSE6614 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
AK4 adenylate kinase 4 3.39415
GM2A GM2 ganglioside activator 3.37379
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 3.23203
FOSB FBJ murine osteosarcoma viral oncogene homolog B 3.18691
NR4A1 nuclear receptor subfamily 4, group A, member 1 3.05748
WDR92 WD repeat domain 92 3.0491
SC5D sterol-C5-desaturase 2.97396
DDIT4 DNA-damage-inducible transcript 4 2.85306
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 2.79141
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 2.78824
MCRS1 microspherule protein 1 2.71494
REEP5 receptor accessory protein 5 2.67919
ACTG1 actin gamma 1 2.66445
ERRFI1 ERBB receptor feedback inhibitor 1 2.65817
NOV nephroblastoma overexpressed 2.63375
SSTR2 somatostatin receptor 2 2.6174
PTCD3 pentatricopeptide repeat domain 3 2.60926
EGR2 early growth response 2 2.56245
ATF3 activating transcription factor 3 2.53705
KLF10 Kruppel-like factor 10 2.53108
PDS5B PDS5 cohesin associated factor B 2.5107
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 2.50262
EPHB6 EPH receptor B6 2.49815
METTL8 methyltransferase like 8 2.49652
PHYH phytanoyl-CoA 2-hydroxylase 2.47792
MIDN midnolin 2.44979
STX7 syntaxin 7 2.4332
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.41237
SDPR serum deprivation response 2.40231
ACVR2B activin A receptor, type IIB 2.38668
USP9X ubiquitin specific peptidase 9, X-linked 2.37023
RBMX RNA binding motif protein, X-linked 2.36113
SF3A3 splicing factor 3a, subunit 3, 60kDa 2.35452
GLTP glycolipid transfer protein 2.3312
SYNJ2BP synaptojanin 2 binding protein 2.32877
PLK2 polo-like kinase 2 2.31208
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 2.31203
BTG2 BTG family, member 2 2.29498
WDR26 WD repeat domain 26 2.29249
PRDX2 peroxiredoxin 2 2.29244
PPT2 palmitoyl-protein thioesterase 2 2.2889
SAT1 spermidine/spermine N1-acetyltransferase 1 2.26884
EXOC7 exocyst complex component 7 2.2658
YIPF1 Yip1 domain family, member 1 2.25857
FGGY FGGY carbohydrate kinase domain containing 2.2583
PCF11 PCF11 cleavage and polyadenylation factor subunit 2.24174
ARMCX2 armadillo repeat containing, X-linked 2 2.23928
ILK integrin-linked kinase 2.23849
GALK2 galactokinase 2 2.23423
FRMD6 FERM domain containing 6 2.23364
F3 coagulation factor III (thromboplastin, tissue factor) 2.22326
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.22239
LXN latexin 2.22122
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.21934
WDFY2 WD repeat and FYVE domain containing 2 2.21766
TMEM183A transmembrane protein 183A 2.20191
PNKD paroxysmal nonkinesigenic dyskinesia 2.1996
ANKRD33B ankyrin repeat domain 33B 2.19901
STMN4 stathmin-like 4 2.19887
RAB11B RAB11B, member RAS oncogene family 2.19436
RAE1 ribonucleic acid export 1 2.1931
ITGB1BP1 integrin beta 1 binding protein 1 2.19009
AMZ2 archaelysin family metallopeptidase 2 2.17766
RCOR2 REST corepressor 2 2.17088
FOS FBJ murine osteosarcoma viral oncogene homolog 2.15805
RASL11B RAS-like, family 11, member B 2.15774
INPP5F inositol polyphosphate-5-phosphatase F 2.1542
MRPL48 mitochondrial ribosomal protein L48 2.15109
TNIP1 TNFAIP3 interacting protein 1 2.14085
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 2.13899
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) 2.11057
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 2.10919
LYRM2 LYR motif containing 2 2.09603
CLTC clathrin, heavy chain (Hc) 2.09355
SERBP1 SERPINE1 mRNA binding protein 1 2.09338
LITAF lipopolysaccharide-induced TNF factor 2.07781
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 2.07619
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.06698
C1ORF43 chromosome 1 open reading frame 43 2.0659
CD9 CD9 molecule 2.05982
GPX4 glutathione peroxidase 4 2.0572
TSPAN6 tetraspanin 6 2.04213
UBE2D3 ubiquitin-conjugating enzyme E2D 3 2.01699
STK40 serine/threonine kinase 40 2.00716
ELAC2 elaC ribonuclease Z 2 1.99517
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 1.99472
SKAP2 src kinase associated phosphoprotein 2 1.98603
NSDHL NAD(P) dependent steroid dehydrogenase-like 1.97773
LBP lipopolysaccharide binding protein 1.96573
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 1.95941
CCT2 chaperonin containing TCP1, subunit 2 (beta) 1.95554
KRT12 keratin 12, type I 1.95203
MRPS36 mitochondrial ribosomal protein S36 1.94886
CLIC4 chloride intracellular channel 4 1.94555
GADD45B growth arrest and DNA-damage-inducible, beta 1.94267
DGCR2 DiGeorge syndrome critical region gene 2 1.9423
FAM173A family with sequence similarity 173, member A 1.93948
CCNDBP1 cyclin D-type binding-protein 1 1.93416
FXYD1 FXYD domain containing ion transport regulator 1 1.93404
ALLC allantoicase 1.93374
KLF9 Kruppel-like factor 9 1.92367
CNPY2 canopy FGF signaling regulator 2 1.92339
SFR1 SWI5-dependent recombination repair 1 1.89071
WBP2 WW domain binding protein 2 1.88868
LONP1 lon peptidase 1, mitochondrial 1.88738
IGBP1 immunoglobulin (CD79A) binding protein 1 1.88123
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 1.87851
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 1.87772
RIT1 Ras-like without CAAX 1 1.87771
API5 apoptosis inhibitor 5 1.8753
PRUNE prune exopolyphosphatase 1.87141
RAMP3 receptor (G protein-coupled) activity modifying protein 3 1.8658
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.85363
TST thiosulfate sulfurtransferase (rhodanese) 1.85065
SGK1 serum/glucocorticoid regulated kinase 1 1.8505
TXNIP thioredoxin interacting protein 1.84798
COPS4 COP9 signalosome subunit 4 1.83924
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 1.83818
JUNB jun B proto-oncogene 1.83332
GPR37L1 G protein-coupled receptor 37 like 1 1.82961
UBC ubiquitin C 1.82877
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 1.82835
CA2 carbonic anhydrase II 1.82773
COMT catechol-O-methyltransferase 1.82501
MEST mesoderm specific transcript 1.81892
TUBB6 tubulin, beta 6 class V 1.81197
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.80516
TCERG1 transcription elongation regulator 1 1.80448
CRYZ crystallin, zeta (quinone reductase) 1.80338
PTPRE protein tyrosine phosphatase, receptor type, E 1.79332
ILVBL ilvB (bacterial acetolactate synthase)-like 1.78916
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 1.78886
STMN2 stathmin 2 1.78803
PHKG1 phosphorylase kinase, gamma 1 (muscle) 1.78533
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.78359
OCIAD1 OCIA domain containing 1 1.78251
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.77909
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 1.77435
MRPS18A mitochondrial ribosomal protein S18A 1.76702
MYT1L myelin transcription factor 1-like 1.75846
APRT adenine phosphoribosyltransferase 1.75461
LEPROT leptin receptor overlapping transcript 1.74918
RPL21 ribosomal protein L21 1.74685
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.74232
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.73686
SLBP stem-loop binding protein 1.73594
NEK6 NIMA-related kinase 6 1.73532
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 1.73505
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 1.73465
SEC16A SEC16 homolog A (S. cerevisiae) 1.73327
DPF2 D4, zinc and double PHD fingers family 2 1.72931
C9ORF16 chromosome 9 open reading frame 16 1.72764
EFNB3 ephrin-B3 1.72371
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 1.71678
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 1.71472
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 1.71418
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 1.7129
BGN biglycan 1.71212
CCDC12 coiled-coil domain containing 12 1.71152
MYO6 myosin VI 1.70834
GRPEL2 GrpE-like 2, mitochondrial (E. coli) 1.70747
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 1.70444
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.7005
RASD1 RAS, dexamethasone-induced 1 1.69847
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 1.69723
PLAA phospholipase A2-activating protein 1.69219
CLOCK clock circadian regulator 1.69173
RPAP1 RNA polymerase II associated protein 1 1.69081
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 1.68901
SELPLG selectin P ligand 1.68557
CTGF connective tissue growth factor 1.68387
COL19A1 collagen, type XIX, alpha 1 1.68267
ZC3H11A zinc finger CCCH-type containing 11A 1.68015
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.67913
PHF5A PHD finger protein 5A 1.66796
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.66563
PPAN peter pan homolog (Drosophila) 1.66425
S100B S100 calcium binding protein B 1.66319
WNT3 wingless-type MMTV integration site family, member 3 1.6622
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) 1.66085
IL27RA interleukin 27 receptor, alpha 1.65848
CDK18 cyclin-dependent kinase 18 1.64963
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 1.6492
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 1.64614
BTF3 basic transcription factor 3 1.64585
CUL1 cullin 1 1.64413
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) 1.64314
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 1.64279
TUBA4A tubulin, alpha 4a 1.64169
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 1.63638
POT1 protection of telomeres 1 1.63325
MSN moesin 1.63271
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.63184
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 1.62859
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.6234
SEPHS2 selenophosphate synthetase 2 1.62284
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 1.62207
ETF1 eukaryotic translation termination factor 1 1.62102
COL10A1 collagen, type X, alpha 1 1.61971
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.61818
RSU1 Ras suppressor protein 1 1.61627
DUSP1 dual specificity phosphatase 1 1.61486
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 1.61445
CORT cortistatin 1.61345
TACR2 tachykinin receptor 2 1.608
EMP1 epithelial membrane protein 1 1.60601
JUN jun proto-oncogene 1.60598
PLXND1 plexin D1 1.60288
TOX4 TOX high mobility group box family member 4 1.59565
SOS1 son of sevenless homolog 1 (Drosophila) 1.59446
MRPS15 mitochondrial ribosomal protein S15 1.58898
MDK midkine (neurite growth-promoting factor 2) 1.58721
RYR3 ryanodine receptor 3 1.58408
ZAN zonadhesin (gene/pseudogene) 1.58406
CD59 CD59 molecule, complement regulatory protein 1.58184
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 1.57774
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 1.57754
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 1.57697
NKAIN1 Na+/K+ transporting ATPase interacting 1 1.57638
SELV selenoprotein V 1.57566
FSHR follicle stimulating hormone receptor 1.57469
IMMT inner membrane protein, mitochondrial 1.5737
WNT8A wingless-type MMTV integration site family, member 8A 1.57316
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.57286
RASAL1 RAS protein activator like 1 (GAP1 like) 1.57113
MTM1 myotubularin 1 1.56788
CYR61 cysteine-rich, angiogenic inducer, 61 1.56621
MCM3 minichromosome maintenance complex component 3 1.5653
ERMP1 endoplasmic reticulum metallopeptidase 1 1.56523
MDFIC MyoD family inhibitor domain containing 1.56506
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 1.56486
NECAP1 NECAP endocytosis associated 1 1.56246
FAM69B family with sequence similarity 69, member B 1.55987
EIF3K eukaryotic translation initiation factor 3, subunit K 1.55711
TRPM1 transient receptor potential cation channel, subfamily M, member 1 1.55605
LARP1 La ribonucleoprotein domain family, member 1 1.55595
PPA1 pyrophosphatase (inorganic) 1 1.55585
IER2 immediate early response 2 1.55569
CSE1L CSE1 chromosome segregation 1-like (yeast) 1.55408
PER1 period circadian clock 1 1.55292
GATA2 GATA binding protein 2 1.55184
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.55179
BCAP29 B-cell receptor-associated protein 29 1.55128
HLA-DRA major histocompatibility complex, class II, DR alpha 1.55066
DHODH dihydroorotate dehydrogenase (quinone) 1.55064
HMOX2 heme oxygenase 2 1.54888
GSTO1 glutathione S-transferase omega 1 1.54876
SEPT7 septin 7 1.54629
ENPEP glutamyl aminopeptidase (aminopeptidase A) 1.54585
C9ORF91 chromosome 9 open reading frame 91 1.54289
RPL27A ribosomal protein L27a 1.53672
ETFB electron-transfer-flavoprotein, beta polypeptide 1.53638
THBS1 thrombospondin 1 1.53152
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.52823
NDRG1 N-myc downstream regulated 1 1.52809
FRMD8 FERM domain containing 8 1.52782
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.52586
SURF1 surfeit 1 1.52449
SELK selenoprotein K 1.52274
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 1.52254
PRSS23 protease, serine, 23 1.52115
SH3PXD2A SH3 and PX domains 2A 1.51936
ZCCHC3 zinc finger, CCHC domain containing 3 1.51917
COPS5 COP9 signalosome subunit 5 1.51513
LAMA5 laminin, alpha 5 1.51487
BHLHE40 basic helix-loop-helix family, member e40 1.50868
RCN1 reticulocalbin 1, EF-hand calcium binding domain 1.50832
NCOA3 nuclear receptor coactivator 3 1.50752
SCG5 secretogranin V 1.50548
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 1.50256
WBP5 WW domain binding protein 5 1.50226
APAF1 apoptotic peptidase activating factor 1 1.50196
RFC1 replication factor C (activator 1) 1, 145kDa 1.50191
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 1.50028
RB1 retinoblastoma 1 1.49975
POLB polymerase (DNA directed), beta 1.49566
FGFR2 fibroblast growth factor receptor 2 1.49025
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.48898
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 1.48845
FRMD5 FERM domain containing 5 1.48773
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa 1.4877
GCSH glycine cleavage system protein H (aminomethyl carrier) 1.48386
CKAP5 cytoskeleton associated protein 5 1.483
RGS2 regulator of G-protein signaling 2 1.48271
DAZ2 deleted in azoospermia 2 1.48137
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.47944
ELL2 elongation factor, RNA polymerase II, 2 1.47871
EGR1 early growth response 1 1.47494
RPL10A ribosomal protein L10a 1.4717
C15ORF39 chromosome 15 open reading frame 39 1.47125
SSPO SCO-spondin 1.47011
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.47004
ACTB actin, beta 1.46935
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 1.46837
PEX2 peroxisomal biogenesis factor 2 1.46687
ZNF148 zinc finger protein 148 1.46672
CELA1 chymotrypsin-like elastase family, member 1 1.46551
LIG1 ligase I, DNA, ATP-dependent 1.46456
EXOSC4 exosome component 4 1.46366
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.46237

decreased expression

Symbol Name Standardized Value
ZNF598 zinc finger protein 598 -3.6696
BECN1 beclin 1, autophagy related -3.32835
PCBP2 poly(rC) binding protein 2 -3.2354
RALBP1 ralA binding protein 1 -3.22794
WDR81 WD repeat domain 81 -3.1441
VPRBP Vpr (HIV-1) binding protein -3.07113
DLX5 distal-less homeobox 5 -2.99207
ADCY9 adenylate cyclase 9 -2.9868
SOX18 SRY (sex determining region Y)-box 18 -2.9109
H2AFV H2A histone family, member V -2.83253
RERE arginine-glutamic acid dipeptide (RE) repeats -2.78897
RNF145 ring finger protein 145 -2.76585
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.69774
INTS5 integrator complex subunit 5 -2.62431
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -2.59661
CTNND2 catenin (cadherin-associated protein), delta 2 -2.58347
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -2.55883
ZBTB45 zinc finger and BTB domain containing 45 -2.55547
NUP107 nucleoporin 107kDa -2.54477
CDC42SE1 CDC42 small effector 1 -2.51064
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -2.49939
IRF8 interferon regulatory factor 8 -2.48952
CA14 carbonic anhydrase XIV -2.47096
UNC50 unc-50 homolog (C. elegans) -2.4633
ZNF35 zinc finger protein 35 -2.41524
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.41082
IRGM immunity-related GTPase family, M -2.39929
PNPLA2 patatin-like phospholipase domain containing 2 -2.37279
CDAN1 codanin 1 -2.3648
CAMK2B calcium/calmodulin-dependent protein kinase II beta -2.3458
INTS3 integrator complex subunit 3 -2.33586
MRPL28 mitochondrial ribosomal protein L28 -2.33021
CCNL2 cyclin L2 -2.31191
FLOT1 flotillin 1 -2.29605
UBE2K ubiquitin-conjugating enzyme E2K -2.29257
CDC23 cell division cycle 23 -2.29235
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.27683
NUP50 nucleoporin 50kDa -2.27434
NANS N-acetylneuraminic acid synthase -2.26474
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -2.26131
TULP3 tubby like protein 3 -2.25621
RPIA ribose 5-phosphate isomerase A -2.23878
ELMOD3 ELMO/CED-12 domain containing 3 -2.23573
POU2F1 POU class 2 homeobox 1 -2.21304
FLCN folliculin -2.21126
MKL1 megakaryoblastic leukemia (translocation) 1 -2.19966
PERP PERP, TP53 apoptosis effector -2.18234
PHTF1 putative homeodomain transcription factor 1 -2.15965
KLF6 Kruppel-like factor 6 -2.15487
JAM3 junctional adhesion molecule 3 -2.15383
LSM1 LSM1, U6 small nuclear RNA associated -2.15112
PGM1 phosphoglucomutase 1 -2.14891
WRNIP1 Werner helicase interacting protein 1 -2.14341
TGDS TDP-glucose 4,6-dehydratase -2.14104
KIAA0368 KIAA0368 -2.11424
FAM63A family with sequence similarity 63, member A -2.1059
RNF34 ring finger protein 34, E3 ubiquitin protein ligase -2.10284
RNASEH2C ribonuclease H2, subunit C -2.09449
ATXN7L3 ataxin 7-like 3 -2.09403
SETD6 SET domain containing 6 -2.08653
TBK1 TANK-binding kinase 1 -2.08182
TSPAN33 tetraspanin 33 -2.08141
KIFAP3 kinesin-associated protein 3 -2.07999
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -2.0773
UNCX UNC homeobox -2.07163
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -2.06985
STK11 serine/threonine kinase 11 -2.0675
SRRT serrate, RNA effector molecule -2.06214
PROS1 protein S (alpha) -2.05846
POR P450 (cytochrome) oxidoreductase -2.05788
RRP1B ribosomal RNA processing 1B -2.0498
PHC1 polyhomeotic homolog 1 (Drosophila) -2.04303
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.03871
TFCP2L1 transcription factor CP2-like 1 -2.02387
FBXO21 F-box protein 21 -2.02208
INPPL1 inositol polyphosphate phosphatase-like 1 -2.02083
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -2.01085
FLII flightless I homolog (Drosophila) -1.99972
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -1.99708
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 -1.99155
RCAN3 RCAN family member 3 -1.98868
GUSB glucuronidase, beta -1.98867
DTYMK deoxythymidylate kinase (thymidylate kinase) -1.98649
UBN1 ubinuclein 1 -1.98205
NGRN neugrin, neurite outgrowth associated -1.977
WNK2 WNK lysine deficient protein kinase 2 -1.97268
C9ORF72 chromosome 9 open reading frame 72 -1.9721
MDN1 MDN1, midasin homolog (yeast) -1.962
MAPK14 mitogen-activated protein kinase 14 -1.95704
USP39 ubiquitin specific peptidase 39 -1.92941
ATF5 activating transcription factor 5 -1.92632
DYNLRB1 dynein, light chain, roadblock-type 1 -1.92376
ADAM9 ADAM metallopeptidase domain 9 -1.91682
TMEM179B transmembrane protein 179B -1.91095
TWSG1 twisted gastrulation BMP signaling modulator 1 -1.90806
CD300C CD300c molecule -1.90137
RGS19 regulator of G-protein signaling 19 -1.89454
IL10RB interleukin 10 receptor, beta -1.89437
AOC3 amine oxidase, copper containing 3 -1.8924
ITPK1 inositol-tetrakisphosphate 1-kinase -1.88856
ARHGAP39 Rho GTPase activating protein 39 -1.88352
DIAPH1 diaphanous-related formin 1 -1.88168
TMEM43 transmembrane protein 43 -1.88124
YPEL3 yippee-like 3 (Drosophila) -1.88059
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -1.87905
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 -1.87711
CCNC cyclin C -1.87531
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -1.87411
MSH2 mutS homolog 2 -1.873
GOLGA5 golgin A5 -1.87281
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 -1.87155
MRPL45 mitochondrial ribosomal protein L45 -1.87152
SREBF1 sterol regulatory element binding transcription factor 1 -1.86813
TRIM11 tripartite motif containing 11 -1.86187
XPO1 exportin 1 -1.84661
SNIP1 Smad nuclear interacting protein 1 -1.8431
ERO1L ERO1-like (S. cerevisiae) -1.83355
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -1.83351
SPATA13 spermatogenesis associated 13 -1.82096
SORBS1 sorbin and SH3 domain containing 1 -1.81944
JMJD6 jumonji domain containing 6 -1.81703
MRPL43 mitochondrial ribosomal protein L43 -1.81696
CRLF3 cytokine receptor-like factor 3 -1.81589
CLK1 CDC-like kinase 1 -1.81487
CASP2 caspase 2, apoptosis-related cysteine peptidase -1.80844
TNK2 tyrosine kinase, non-receptor, 2 -1.80577
DOCK5 dedicator of cytokinesis 5 -1.80165
MED23 mediator complex subunit 23 -1.80158
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -1.80061
CLK2 CDC-like kinase 2 -1.7987
RNF166 ring finger protein 166 -1.79085
ZNF703 zinc finger protein 703 -1.77858
C7ORF43 chromosome 7 open reading frame 43 -1.77215
ACRC acidic repeat containing -1.7612
NT5DC2 5'-nucleotidase domain containing 2 -1.75944
WDR13 WD repeat domain 13 -1.75761
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -1.75457
KIAA1161 KIAA1161 -1.75067
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -1.74976
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -1.74636
ARF1 ADP-ribosylation factor 1 -1.73919
MAN2C1 mannosidase, alpha, class 2C, member 1 -1.73324
UGDH UDP-glucose 6-dehydrogenase -1.73286
BUB3 BUB3 mitotic checkpoint protein -1.73046
UNC119 unc-119 homolog (C. elegans) -1.72632
SETD8 SET domain containing (lysine methyltransferase) 8 -1.72572
TGFB3 transforming growth factor, beta 3 -1.71565
EXT1 exostosin glycosyltransferase 1 -1.71221
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -1.70815
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -1.70685
TRIM59 tripartite motif containing 59 -1.70245
MOB1B MOB kinase activator 1B -1.70178
SHE Src homology 2 domain containing E -1.70037
RAMP2 receptor (G protein-coupled) activity modifying protein 2 -1.70026
HIST1H2BI histone cluster 1, H2bi -1.70021
IARS isoleucyl-tRNA synthetase -1.69842
CRNKL1 crooked neck pre-mRNA splicing factor 1 -1.69666
BCAN brevican -1.68947
SCMH1 sex comb on midleg homolog 1 (Drosophila) -1.67746
LMNB2 lamin B2 -1.67686
SPOP speckle-type POZ protein -1.6752
NEFH neurofilament, heavy polypeptide -1.67452
SNX1 sorting nexin 1 -1.67168
SH2B3 SH2B adaptor protein 3 -1.6706
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -1.66968
DCAF8 DDB1 and CUL4 associated factor 8 -1.66596
ZFP90 ZFP90 zinc finger protein -1.66371
TSNAX translin-associated factor X -1.66104
TPD52L2 tumor protein D52-like 2 -1.6523
OSBP oxysterol binding protein -1.6518
STARD7 StAR-related lipid transfer (START) domain containing 7 -1.65176
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -1.64917
NKIRAS1 NFKB inhibitor interacting Ras-like 1 -1.6414
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit -1.63915
C17ORF96 chromosome 17 open reading frame 96 -1.63781
MRPS22 mitochondrial ribosomal protein S22 -1.63689
NPC1 Niemann-Pick disease, type C1 -1.63459
TADA1 transcriptional adaptor 1 -1.63446
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.63324
IFI16 interferon, gamma-inducible protein 16 -1.63057
NMD3 NMD3 ribosome export adaptor -1.62814
BRD8 bromodomain containing 8 -1.62313
PHF12 PHD finger protein 12 -1.62313
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -1.62232
PTPN21 protein tyrosine phosphatase, non-receptor type 21 -1.62026
PRKACB protein kinase, cAMP-dependent, catalytic, beta -1.62024
FGFR1 fibroblast growth factor receptor 1 -1.61811
C12ORF57 chromosome 12 open reading frame 57 -1.61675
HSPB2 heat shock 27kDa protein 2 -1.60882
HLA-DMA major histocompatibility complex, class II, DM alpha -1.60759
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) -1.60392
KLF5 Kruppel-like factor 5 (intestinal) -1.60144
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -1.60143
SLC25A39 solute carrier family 25, member 39 -1.59976
TYSND1 trypsin domain containing 1 -1.59863
KIAA0930 KIAA0930 -1.59777
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -1.5963
AP3M1 adaptor-related protein complex 3, mu 1 subunit -1.59335
GFER growth factor, augmenter of liver regeneration -1.59285
VRK3 vaccinia related kinase 3 -1.58738
TOP3B topoisomerase (DNA) III beta -1.58732
SLMO2 slowmo homolog 2 (Drosophila) -1.58026
MAF1 MAF1 homolog (S. cerevisiae) -1.57687
FOXRED1 FAD-dependent oxidoreductase domain containing 1 -1.57352
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) -1.57318
BYSL bystin-like -1.57232
COPS7B COP9 signalosome subunit 7B -1.57151
PTTG1 pituitary tumor-transforming 1 -1.56868
HTT huntingtin -1.56812
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -1.56781
LPIN1 lipin 1 -1.56575
MAN2A1 mannosidase, alpha, class 2A, member 1 -1.56339
TBX6 T-box 6 -1.55497
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -1.55222
MSL1 male-specific lethal 1 homolog (Drosophila) -1.55128
CASP8AP2 caspase 8 associated protein 2 -1.54821
COMTD1 catechol-O-methyltransferase domain containing 1 -1.54818
GTF2A1 general transcription factor IIA, 1, 19/37kDa -1.54788
ZBTB46 zinc finger and BTB domain containing 46 -1.5477
ERN2 endoplasmic reticulum to nucleus signaling 2 -1.54757
TESK1 testis-specific kinase 1 -1.54734
HNRNPM heterogeneous nuclear ribonucleoprotein M -1.54573
SFXN2 sideroflexin 2 -1.54444
NCOA1 nuclear receptor coactivator 1 -1.54127
MAN1A1 mannosidase, alpha, class 1A, member 1 -1.53806
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 -1.53496
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -1.53441
SPRYD4 SPRY domain containing 4 -1.53384
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase -1.53235
ZFR zinc finger RNA binding protein -1.53196
GPAM glycerol-3-phosphate acyltransferase, mitochondrial -1.53073
MED20 mediator complex subunit 20 -1.52553
ENG endoglin -1.52452
ANGEL2 angel homolog 2 (Drosophila) -1.52295
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -1.5229
HIST1H2BA histone cluster 1, H2ba -1.52289
CTCF CCCTC-binding factor (zinc finger protein) -1.5216
VWF von Willebrand factor -1.51775
ERO1LB ERO1-like beta (S. cerevisiae) -1.51429
FKBP4 FK506 binding protein 4, 59kDa -1.51404
NDE1 nudE neurodevelopment protein 1 -1.51197
SS18 synovial sarcoma translocation, chromosome 18 -1.51183
EI24 etoposide induced 2.4 -1.51038
XPOT exportin, tRNA -1.51001
HP1BP3 heterochromatin protein 1, binding protein 3 -1.50965
ASB6 ankyrin repeat and SOCS box containing 6 -1.50426
ANKRD10 ankyrin repeat domain 10 -1.50043
FAM136A family with sequence similarity 136, member A -1.49786
SCD stearoyl-CoA desaturase (delta-9-desaturase) -1.49677
FAM192A family with sequence similarity 192, member A -1.49432
TRIO trio Rho guanine nucleotide exchange factor -1.4929
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -1.48542
NCOR2 nuclear receptor corepressor 2 -1.48313
ITM2C integral membrane protein 2C -1.4826
RCSD1 RCSD domain containing 1 -1.48154
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa -1.48105
EMG1 EMG1 N1-specific pseudouridine methyltransferase -1.48025
PNRC2 proline-rich nuclear receptor coactivator 2 -1.47935
NXN nucleoredoxin -1.47784
LCT lactase -1.47698
SNX9 sorting nexin 9 -1.4751
ZNFX1 zinc finger, NFX1-type containing 1 -1.47486
RPS19 ribosomal protein S19 -1.471
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) -1.4677
GCK glucokinase (hexokinase 4) -1.46316
TTC30B tetratricopeptide repeat domain 30B -1.46285
DICER1 dicer 1, ribonuclease type III -1.46125
CECR6 cat eye syndrome chromosome region, candidate 6 -1.46054
UHRF1BP1 UHRF1 binding protein 1 -1.45792
PABPC1 poly(A) binding protein, cytoplasmic 1 -1.45763
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -1.454
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -1.45372
MED12 mediator complex subunit 12 -1.45107
ENAH enabled homolog (Drosophila) -1.4479
TXNRD1 thioredoxin reductase 1 -1.44266
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -1.43763
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -1.43615
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -1.43611
ZMYND8 zinc finger, MYND-type containing 8 -1.4357
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -1.43377
NCBP1 nuclear cap binding protein subunit 1, 80kDa -1.43317
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -1.43305
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 -1.43294
YIPF4 Yip1 domain family, member 4 -1.43112
POLR1B polymerase (RNA) I polypeptide B, 128kDa -1.42917
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -1.42582
GARS glycyl-tRNA synthetase -1.42427
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -1.42353
RPP14 ribonuclease P/MRP 14kDa subunit -1.42199
RPA3 replication protein A3, 14kDa -1.41979
MEA1 male-enhanced antigen 1 -1.41884
SART3 squamous cell carcinoma antigen recognized by T cells 3 -1.41683
BANP BTG3 associated nuclear protein -1.40796
RSPO2 R-spondin 2 -1.40716
UIMC1 ubiquitin interaction motif containing 1 -1.40703
TUSC2 tumor suppressor candidate 2 -1.40693
ANLN anillin, actin binding protein -1.40529
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -1.40228
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -1.39668
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -1.39628