Giant Cell Arteritis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0039483
Similar Terms
Downloads & Tools

Genes

243 genes associated with the disease Giant Cell Arteritis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ACR acrosin
ACTB actin, beta
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALB albumin
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANXA1 annexin A1
ARHGAP24 Rho GTPase activating protein 24
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
BLK BLK proto-oncogene, Src family tyrosine kinase
C1ORF228 chromosome 1 open reading frame 228
C6ORF10 chromosome 6 open reading frame 10
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC6 coiled-coil domain containing 6
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCN1 cellular communication network factor 1
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD226 CD226 molecule
CD24 CD24 molecule
CD274 CD274 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD6 CD6 molecule
CD68 CD68 molecule
CD83 CD83 molecule
CDCA5 cell division cycle associated 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
COL18A1 collagen, type XVIII, alpha 1
COX2
CRH corticotropin releasing hormone
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSK c-src tyrosine kinase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
DAP death-associated protein
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EBNA1BP2 EBNA1 binding protein 2
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
ELN elastin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC5 excision repair cross-complementation group 5
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F9 coagulation factor IX
FAF1 Fas (TNFRSF6) associated factor 1
FAM167A family with sequence similarity 167, member A
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF13 fibroblast growth factor 13
FGF2 fibroblast growth factor 2 (basic)
FIP1L1 factor interacting with PAPOLA and CPSF1
FOLR2 folate receptor 2 (fetal)
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GCA grancalcin, EF-hand calcium binding protein
GCHFR GTP cyclohydrolase I feedback regulator
GYPA glycophorin A (MNS blood group)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLTF helicase-like transcription factor
ICAM1 intercellular adhesion molecule 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL12A interleukin 12A
IL12RB2 interleukin 12 receptor, beta 2
IL17A interleukin 17A
IL17D interleukin 17D
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL21R interleukin 21 receptor
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL3 interleukin 3
IL31 interleukin 31
IL32 interleukin 32
IL33 interleukin 33
IL33R interleukin 33 receptor
IL37 interleukin 37
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
IL9 interleukin 9
IRAK1 interleukin-1 receptor-associated kinase 1
IRF5 interferon regulatory factor 5
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAG1 jagged 1
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT15 keratin 15, type I
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LMLN leishmanolysin-like (metallopeptidase M8 family)
LMNA lamin A/C
LOC105375355 uroplakin-3b
LTB lymphotoxin beta (TNF superfamily, member 3)
MAPK1 mitogen-activated protein kinase 1
MAPK8 mitogen-activated protein kinase 8
MBD4 methyl-CpG binding domain protein 4
MBL2 mannose-binding lectin (protein C) 2, soluble
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MFGE8 milk fat globule-EGF factor 8 protein
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MNAT1 MNAT CDK-activating kinase assembly factor 1
MOCOS molybdenum cofactor sulfurase
MPO myeloperoxidase
MSMB microseminoprotein, beta-
MST1 macrophage stimulating 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MX1 MX dynamin-like GTPase 1
MYDGF myeloid-derived growth factor
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PARK2 parkin RBR E3 ubiquitin protein ligase
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PEBP1 phosphatidylethanolamine binding protein 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCE1 phospholipase C, epsilon 1
PLCL1 phospholipase C-like 1
PLG plasminogen
POU2F3 POU class 2 homeobox 3
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTX3 pentraxin 3, long
RABEPK Rab9 effector protein with kelch motifs
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RASSF6 Ras association (RalGDS/AF-6) domain family member 6
RBM45 RNA binding motif protein 45
REG1A regenerating islet-derived 1 alpha
RHCE Rh blood group, CcEe antigens
RPL17 ribosomal protein L17
RPL17-C18ORF32 RPL17-C18orf32 readthrough
RPSA ribosomal protein SA
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SELE selectin E
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SETD2 SET domain containing 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC12A9 solute carrier family 12, member 9
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
SMAD4 SMAD family member 4
SMCP sperm mitochondria-associated cysteine-rich protein
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPATA2 spermatogenesis associated 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT4 signal transducer and activator of transcription 4
TAZ tafazzin
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TLR4 toll-like receptor 4
TMPRSS13 transmembrane protease, serine 13
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TRAF1 TNF receptor-associated factor 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TYMS thymidylate synthetase
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
WWOX WW domain containing oxidoreductase
WWTR1 WW domain containing transcription regulator 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZC4H2 zinc finger, C4H2 domain containing
ZNF645 zinc finger protein 645