Gilles De La Tourette Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A tic disorder that is characterized by multiple physical (motor) tics and at least one vocal (phonic) tic present for more than a year. (Human Disease Ontology, DOID_11119)
External Link https://www.disgenet.org/browser/0/1/0/C0040517
Similar Terms
Downloads & Tools

Genes

169 genes associated with the disease Gilles De La Tourette Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AADAC arylacetamide deacetylase
ACP1 acid phosphatase 1, soluble
ADD2 adducin 2 (beta)
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADRA1A adrenoceptor alpha 1A
ADRA2A adrenoceptor alpha 2A
ALG9 ALG9, alpha-1,2-mannosyltransferase
AMELX amelogenin, X-linked
ANKK1 ankyrin repeat and kinase domain containing 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD1 ATPase family, AAA domain containing 1
BDNF brain-derived neurotrophic factor
BTBD9 BTB (POZ) domain containing 9
C1QBP complement component 1, q subcomponent binding protein
CBLN2 cerebellin 2 precursor
CCL2 chemokine (C-C motif) ligand 2
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CD69 CD69 molecule
CD8A CD8a molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDX2 caudal type homeobox 2
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CHAT choline O-acetyltransferase
CHD2 chromodomain helicase DNA binding protein 2
CHM choroideremia (Rab escort protein 1)
CHPT1 choline phosphotransferase 1
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CNR1 cannabinoid receptor 1 (brain)
CNTN6 contactin 6
CNTNAP2 contactin associated protein-like 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL27A1 collagen, type XXVII, alpha 1
COL8A1 collagen, type VIII, alpha 1
COMT catechol-O-methyltransferase
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSMD3 CUB and Sushi multiple domains 3
CXCL8 chemokine (C-X-C motif) ligand 8
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DHDDS dehydrodolichyl diphosphate synthase
DLGAP3 discs, large (Drosophila) homolog-associated protein 3
DNTT DNA nucleotidylexotransferase
DPP6 dipeptidyl-peptidase 6
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ENO2 enolase 2 (gamma, neuronal)
F11R F11 receptor
FLT3 fms-related tyrosine kinase 3
FPR3 formyl peptide receptor 3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCH1 GTP cyclohydrolase 1
GDNF glial cell derived neurotrophic factor
GH1 growth hormone 1
GPC5 glypican 5
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRHL3 grainyhead-like 3 (Drosophila)
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
HDC histidine decarboxylase
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
HK1 hexokinase 1
HLA-A major histocompatibility complex, class I, A
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMBS hydroxymethylbilane synthase
HPGDS hematopoietic prostaglandin D synthase
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL12B interleukin 12B
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
ING2 inhibitor of growth family, member 2
JAK2 Janus kinase 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK9 potassium channel, two pore domain subfamily K, member 9
LAMC2 laminin, gamma 2
LCT lactase
LHX6 LIM homeobox 6
LHX8 LIM homeobox 8
LMO3 LIM domain only 3 (rhombotin-like 2)
LRP2 low density lipoprotein receptor-related protein 2
LYPD6 LY6/PLAUR domain containing 6
MAOA monoamine oxidase A
MAP2K5 mitogen-activated protein kinase kinase 5
MCF2L MCF.2 cell line derived transforming sequence-like
MEIS1 Meis homeobox 1
MET MET proto-oncogene, receptor tyrosine kinase
MGST1 microsomal glutathione S-transferase 1
MOG myelin oligodendrocyte glycoprotein
NECTIN1 nectin cell adhesion molecule 1
NFE2L2 nuclear factor, erythroid 2-like 2
NLGN4X neuroligin 4, X-linked
NLRP3 NLR family, pyrin domain containing 3
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRXN1 neurexin 1
NTN4 netrin 4
OGA O-GlcNAcase
OLFM1 olfactomedin 1
OLIG1 oligodendrocyte transcription factor 1
OLIG2 oligodendrocyte lineage transcription factor 2
PARP1 poly (ADP-ribose) polymerase 1
PARP9 poly (ADP-ribose) polymerase family, member 9
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PEX13 peroxisomal biogenesis factor 13
PKM pyruvate kinase, muscle
PNKD paroxysmal nonkinesigenic dyskinesia
POU1F1 POU class 1 homeobox 1
PSD4 pleckstrin and Sec7 domain containing 4
PVALB parvalbumin
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPGRIP1L RPGRIP1-like
SCN2A sodium channel, voltage gated, type II alpha subunit
SCN3A sodium channel, voltage gated, type III alpha subunit
SGCE sarcoglycan, epsilon
SHOX short stature homeobox
SKOR1 SKI family transcriptional corepressor 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLITRK1 SLIT and NTRK-like family, member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPINT1 serine peptidase inhibitor, Kunitz type 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TDO2 tryptophan 2,3-dioxygenase
TDP1 tyrosyl-DNA phosphodiesterase 1
TESC tescalcin
TH tyrosine hydroxylase
TNF tumor necrosis factor
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TPH2 tryptophan hydroxylase 2
TSC1 tuberous sclerosis 1
TYMS thymidylate synthetase
TYR tyrosinase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WAS Wiskott-Aldrich syndrome
WWC1 WW and C2 domain containing 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF577 zinc finger protein 577