| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glasdegib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glasdegib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.121781 |
| RNF149 | ring finger protein 149 | 0.0645327 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0611756 |
| OGA | O-GlcNAcase | 0.0502758 |
| GOLGA4 | golgin A4 | 0.0501769 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0499978 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0471597 |
| RPS6 | ribosomal protein S6 | 0.0467071 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0454373 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0447768 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0440946 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0439141 |
| SBF2 | SET binding factor 2 | 0.0409934 |
| MATR3 | matrin 3 | 0.0364982 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0351466 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0345107 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.034411 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0335665 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0317339 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0313911 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0312247 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0311469 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0308321 |
| TXNIP | thioredoxin interacting protein | 0.0307897 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.030556 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0304501 |
| PTEN | phosphatase and tensin homolog | 0.027957 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.027846 |
| YEATS2 | YEATS domain containing 2 | 0.0275245 |
| PRELID2 | PRELI domain containing 2 | 0.0273118 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0271987 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0267557 |
| AHI1 | Abelson helper integration site 1 | 0.0263939 |
| USP3 | ubiquitin specific peptidase 3 | 0.0260515 |
| ZNF638 | zinc finger protein 638 | 0.0260172 |
| RPL11 | ribosomal protein L11 | 0.0257184 |
| DENND4C | DENN/MADD domain containing 4C | 0.025339 |
| WDR26 | WD repeat domain 26 | 0.0253046 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0252869 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0252708 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0250443 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0250139 |
| ARRDC3 | arrestin domain containing 3 | 0.0249789 |
| RPL26 | ribosomal protein L26 | 0.0243983 |
| MLPH | melanophilin | 0.0241973 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.024143 |
| IFNGR1 | interferon gamma receptor 1 | 0.0240082 |
| RLF | rearranged L-myc fusion | 0.0238531 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0238275 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.023753 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0237136 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.023556 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.023276 |
| NDRG1 | N-myc downstream regulated 1 | 0.0231278 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0230196 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0228833 |
| SUCO | SUN domain containing ossification factor | 0.0227918 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0227314 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0227101 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.022707 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0226972 |
| SMAD3 | SMAD family member 3 | 0.0224572 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.02224 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0219655 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0218524 |
| CEP350 | centrosomal protein 350kDa | 0.0216836 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0212013 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0209626 |
| TNRC6A | trinucleotide repeat containing 6A | 0.020721 |
| AHNAK | AHNAK nucleoprotein | 0.0206591 |
| RBM33 | RNA binding motif protein 33 | 0.0204983 |
| WDR45B | WD repeat domain 45B | 0.0204667 |
| RNF43 | ring finger protein 43 | 0.0204311 |
| EXOC1 | exocyst complex component 1 | 0.0203947 |
| PDS5B | PDS5 cohesin associated factor B | 0.0203848 |
| RPL37A | ribosomal protein L37a | 0.0202881 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0202525 |
| HELZ | helicase with zinc finger | 0.019793 |
| SFXN1 | sideroflexin 1 | 0.0197837 |
| PFKP | phosphofructokinase, platelet | 0.0197803 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.0197107 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0195867 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0195265 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0192395 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0191906 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0189439 |
| PGK1 | phosphoglycerate kinase 1 | 0.0184566 |
| TBPL1 | TBP-like 1 | 0.0184439 |
| SECISBP2L | SECIS binding protein 2-like | 0.0183392 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0182865 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0182037 |
| ZNF451 | zinc finger protein 451 | 0.018181 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0181655 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0180698 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0178753 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0176049 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0175927 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0174926 |
| RNF145 | ring finger protein 145 | 0.0174681 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0173841 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.202196 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.178729 |
| LMO7 | LIM domain 7 | -0.170912 |
| EGR1 | early growth response 1 | -0.138545 |
| RNF213 | ring finger protein 213 | -0.130518 |
| MX1 | MX dynamin-like GTPase 1 | -0.120094 |
| RIGI | RNA sensor RIG-I | -0.119588 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.112439 |
| ANXA2 | annexin A2 | -0.106469 |
| MACC1 | metastasis associated in colon cancer 1 | -0.104228 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.104214 |
| SP100 | SP100 nuclear antigen | -0.104172 |
| MX2 | MX dynamin-like GTPase 2 | -0.100928 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0902774 |
| PLSCR1 | phospholipid scramblase 1 | -0.0888832 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0855774 |
| LYZ | lysozyme | -0.077964 |
| EZR | ezrin | -0.0767403 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0733263 |
| SPATA13 | spermatogenesis associated 13 | -0.0713281 |
| MYO1E | myosin IE | -0.0708931 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0706992 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0700171 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0685413 |
| ITGA6 | integrin, alpha 6 | -0.0684125 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0681181 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0634058 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0621152 |
| JUN | jun proto-oncogene | -0.0619469 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0618439 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0612041 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0611021 |
| B2M | beta-2-microglobulin | -0.0608301 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0593202 |
| TMC5 | transmembrane channel-like 5 | -0.058491 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0580147 |
| INTS6 | integrator complex subunit 6 | -0.0578853 |
| XAF1 | XIAP associated factor 1 | -0.0571996 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0551842 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0547124 |
| NCKAP5 | NCK-associated protein 5 | -0.0540869 |
| VMP1 | vacuole membrane protein 1 | -0.0525644 |
| NPSR1 | neuropeptide S receptor 1 | -0.0521545 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0515863 |
| PMP22 | peripheral myelin protein 22 | -0.0511928 |
| SQSTM1 | sequestosome 1 | -0.0511572 |
| EPHB2 | EPH receptor B2 | -0.0506992 |
| VCL | vinculin | -0.0506624 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0497687 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0491366 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0487094 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.048431 |
| IRF1 | interferon regulatory factor 1 | -0.0463303 |
| AREG | amphiregulin | -0.0462301 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0453292 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0451547 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0451413 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0444742 |
| MCU | mitochondrial calcium uniporter | -0.0442798 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0441256 |
| MECOM | MDS1 and EVI1 complex locus | -0.0433508 |
| TJP1 | tight junction protein 1 | -0.0429216 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0420949 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0420047 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0414408 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.040985 |
| CCNL1 | cyclin L1 | -0.0394849 |
| MUC13 | mucin 13, cell surface associated | -0.0393145 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0388224 |
| PERP | PERP, TP53 apoptosis effector | -0.0383181 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0383034 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0382771 |
| ETV6 | ets variant 6 | -0.0378992 |
| EFNB2 | ephrin-B2 | -0.0378916 |
| LAP3 | leucine aminopeptidase 3 | -0.0376874 |
| ERBIN | erbb2 interacting protein | -0.037556 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0368142 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0364894 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0363864 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0359855 |
| ATP11A | ATPase, class VI, type 11A | -0.034671 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0342975 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0341249 |
| PRKCA | protein kinase C, alpha | -0.0335799 |
| RBM47 | RNA binding motif protein 47 | -0.0329088 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0327734 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0320882 |
| MEIS2 | Meis homeobox 2 | -0.0319127 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0318282 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0317404 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0314733 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0312862 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0311335 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0310992 |
| APOL6 | apolipoprotein L, 6 | -0.0308554 |
| MAP7 | microtubule-associated protein 7 | -0.0307934 |
| FOXP1 | forkhead box P1 | -0.0306909 |
| OCLN | occludin | -0.0306786 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0306513 |
| HLA-B | major histocompatibility complex, class I, B | -0.0305207 |
