| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glasdegib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Glasdegib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.19715 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.113278 |
| MSN | moesin | 0.0783252 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0631898 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0588641 |
| PRELID2 | PRELI domain containing 2 | 0.0587085 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0498724 |
| CAPRIN2 | caprin family member 2 | 0.0492794 |
| RIN2 | Ras and Rab interactor 2 | 0.048758 |
| MYOF | myoferlin | 0.0481018 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0461395 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0413814 |
| NAV2 | neuron navigator 2 | 0.0413194 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0413154 |
| ASPH | aspartate beta-hydroxylase | 0.0408199 |
| PODXL | podocalyxin-like | 0.0406239 |
| SMAD3 | SMAD family member 3 | 0.040541 |
| MTSS1 | metastasis suppressor 1 | 0.0386121 |
| MEF2A | myocyte enhancer factor 2A | 0.0383671 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0377628 |
| OGA | O-GlcNAcase | 0.0352679 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0347638 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0332859 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.032015 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.031229 |
| SLK | STE20-like kinase | 0.0307062 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0302945 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0301119 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0288099 |
| ZNF292 | zinc finger protein 292 | 0.0282192 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.028142 |
| MYO10 | myosin X | 0.0279189 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0272347 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0268886 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0258938 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0254131 |
| YEATS2 | YEATS domain containing 2 | 0.0250991 |
| CUL4B | cullin 4B | 0.0250883 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0249225 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0247456 |
| KIF16B | kinesin family member 16B | 0.024435 |
| C1D | C1D nuclear receptor corepressor | 0.0241971 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.023477 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0234439 |
| PLEC | plectin | 0.0234365 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0228682 |
| YAP1 | Yes-associated protein 1 | 0.0227763 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0226201 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0225545 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0224804 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0223212 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0223052 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0219989 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0219828 |
| RNF19B | ring finger protein 19B | 0.0218772 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0216597 |
| BCL2L1 | BCL2-like 1 | 0.0216481 |
| PCDH1 | protocadherin 1 | 0.021492 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.02147 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0211506 |
| TPM3 | tropomyosin 3 | 0.0210684 |
| ANO6 | anoctamin 6 | 0.0208285 |
| JAG1 | jagged 1 | 0.0207547 |
| ITGA6 | integrin, alpha 6 | 0.0204345 |
| LAMC2 | laminin, gamma 2 | 0.0203988 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0203195 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0202695 |
| DIAPH1 | diaphanous-related formin 1 | 0.0199091 |
| SLTM | SAFB-like, transcription modulator | 0.0198898 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0198446 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0197059 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0196837 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0196708 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0196469 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0193549 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0192678 |
| BLCAP | bladder cancer associated protein | 0.01921 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0189561 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0189534 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0186909 |
| GATA6 | GATA binding protein 6 | 0.0186572 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0186182 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.018487 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0183729 |
| LAMA5 | laminin, alpha 5 | 0.0182728 |
| AMOTL1 | angiomotin like 1 | 0.0181487 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0181416 |
| SUCO | SUN domain containing ossification factor | 0.018116 |
| ZNF638 | zinc finger protein 638 | 0.018071 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0180408 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0180169 |
| INSIG2 | insulin induced gene 2 | 0.0177995 |
| FNIP1 | folliculin interacting protein 1 | 0.0176773 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0175 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0174929 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.017369 |
| MCL1 | myeloid cell leukemia 1 | 0.0172164 |
| CREB1 | cAMP responsive element binding protein 1 | 0.017098 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0170196 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0169943 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.229727 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.212591 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.171532 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.163297 |
| TMSB10 | thymosin beta 10 | -0.111505 |
| PTMA | prothymosin, alpha | -0.10392 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.099888 |
| RPS21 | ribosomal protein S21 | -0.0935834 |
| S100A10 | S100 calcium binding protein A10 | -0.0878076 |
| B2M | beta-2-microglobulin | -0.0871468 |
| MT2A | metallothionein 2A | -0.082337 |
| RPLP1 | ribosomal protein, large, P1 | -0.0817035 |
| LDHA | lactate dehydrogenase A | -0.0804217 |
| HLA-B | major histocompatibility complex, class I, B | -0.0795511 |
| RPS8 | ribosomal protein S8 | -0.0742829 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0731395 |
| TMSB4X | thymosin beta 4, X-linked | -0.0723886 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0720433 |
| RPS24 | ribosomal protein S24 | -0.066934 |
| CD44 | CD44 molecule (Indian blood group) | -0.0636175 |
| RPL35A | ribosomal protein L35a | -0.0634768 |
| GNAS | GNAS complex locus | -0.0618481 |
| H1-0 | H1.0 linker histone | -0.0604861 |
| RPS13 | ribosomal protein S13 | -0.0583379 |
| RPL8 | ribosomal protein L8 | -0.0580453 |
| FTL | ferritin, light polypeptide | -0.057581 |
| RPLP0 | ribosomal protein, large, P0 | -0.0570148 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.056342 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0558797 |
| RPS6 | ribosomal protein S6 | -0.0546302 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0546009 |
| EMP1 | epithelial membrane protein 1 | -0.0545748 |
| RPS19 | ribosomal protein S19 | -0.0540295 |
| RPLP2 | ribosomal protein, large, P2 | -0.0539058 |
| RPS25 | ribosomal protein S25 | -0.0522552 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0513547 |
| RPL34 | ribosomal protein L34 | -0.0512722 |
| RPL12 | ribosomal protein L12 | -0.0484478 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0478428 |
| S100A6 | S100 calcium binding protein A6 | -0.0477588 |
| RPL27A | ribosomal protein L27a | -0.0475703 |
| LMNA | lamin A/C | -0.0475476 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0468604 |
| MT1X | metallothionein 1X | -0.0457918 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.045651 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0456033 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0453002 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0452352 |
| RPS27A | ribosomal protein S27a | -0.0449789 |
| CANX | calnexin | -0.0445678 |
| IGF2 | insulin-like growth factor 2 | -0.0445305 |
| RPL23 | ribosomal protein L23 | -0.0442875 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0442813 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0425075 |
| YBX3 | Y box binding protein 3 | -0.0410449 |
| RPL11 | ribosomal protein L11 | -0.0405902 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0405807 |
| UBC | ubiquitin C | -0.0405091 |
| STC1 | stanniocalcin 1 | -0.0395257 |
| AHNAK | AHNAK nucleoprotein | -0.0392778 |
| YBX1 | Y box binding protein 1 | -0.0391507 |
| RPL31 | ribosomal protein L31 | -0.0390738 |
| MORF4L2 | mortality factor 4 like 2 | -0.0389325 |
| KRT17 | keratin 17, type I | -0.0385674 |
| S100A9 | S100 calcium binding protein A9 | -0.0385246 |
| HLA-E | major histocompatibility complex, class I, E | -0.038346 |
| SULF2 | sulfatase 2 | -0.0382108 |
| PALLD | palladin, cytoskeletal associated protein | -0.0380766 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0375362 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0374816 |
| FOXP1 | forkhead box P1 | -0.0371696 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0368832 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0362675 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0360627 |
| ANXA2 | annexin A2 | -0.0357607 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0357446 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0356996 |
| RPL32 | ribosomal protein L32 | -0.0354204 |
| RPS4X | ribosomal protein S4, X-linked | -0.0353934 |
| S100A11 | S100 calcium binding protein A11 | -0.0352349 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0349382 |
| RIGI | RNA sensor RIG-I | -0.0347835 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0345521 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0345181 |
| TKT | transketolase | -0.0344202 |
| RPS23 | ribosomal protein S23 | -0.0343999 |
| RPL19 | ribosomal protein L19 | -0.0343254 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.034276 |
| CLU | clusterin | -0.0338354 |
| ARF1 | ADP-ribosylation factor 1 | -0.0337478 |
| RPS3 | ribosomal protein S3 | -0.0335538 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0334105 |
| RPL35 | ribosomal protein L35 | -0.0333389 |
| RPS14 | ribosomal protein S14 | -0.0329852 |
| PGK1 | phosphoglycerate kinase 1 | -0.0327949 |
| RPL30 | ribosomal protein L30 | -0.0324107 |
| LMO7 | LIM domain 7 | -0.0323708 |
| RPL28 | ribosomal protein L28 | -0.0323219 |
| HMGA1 | high mobility group AT-hook 1 | -0.0320211 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.031748 |
