| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glasdegib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glasdegib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.155805 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.151476 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.130682 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.10954 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0982791 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0954954 |
| FMNL2 | formin-like 2 | 0.0798244 |
| OGA | O-GlcNAcase | 0.0738308 |
| DST | dystonin | 0.0714079 |
| SET | SET nuclear proto-oncogene | 0.069846 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0645197 |
| CAPRIN2 | caprin family member 2 | 0.0643596 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0622294 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0607709 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0606639 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0605823 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0598696 |
| MATR3 | matrin 3 | 0.0592102 |
| ENO1 | enolase 1, (alpha) | 0.0587776 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0584411 |
| RPS6 | ribosomal protein S6 | 0.0565944 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0565894 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0565549 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0541748 |
| GOLGA4 | golgin A4 | 0.0537495 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0515461 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0513437 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0497439 |
| PRELID2 | PRELI domain containing 2 | 0.0491581 |
| RPS12 | ribosomal protein S12 | 0.0490763 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0488502 |
| MYOF | myoferlin | 0.0482202 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0477671 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0462267 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.044973 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0448546 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0442773 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0440223 |
| TPR | translocated promoter region, nuclear basket protein | 0.0434726 |
| TPM3 | tropomyosin 3 | 0.0434165 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0428537 |
| CDK19 | cyclin-dependent kinase 19 | 0.0420977 |
| CENPF | centromere protein F, 350/400kDa | 0.041368 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0413015 |
| RNF145 | ring finger protein 145 | 0.0411861 |
| RAI1 | retinoic acid induced 1 | 0.0408092 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0407915 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0405215 |
| INSIG2 | insulin induced gene 2 | 0.0403647 |
| NUP58 | nucleoporin 58 | 0.0402941 |
| RPS3 | ribosomal protein S3 | 0.0397786 |
| RPL26 | ribosomal protein L26 | 0.0396659 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0392692 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0383774 |
| SETD5 | SET domain containing 5 | 0.0380863 |
| TXNIP | thioredoxin interacting protein | 0.0378483 |
| PCBP2 | poly(rC) binding protein 2 | 0.0373575 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0372631 |
| RBM25 | RNA binding motif protein 25 | 0.0371547 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0368715 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0367671 |
| FNIP1 | folliculin interacting protein 1 | 0.0363964 |
| YEATS2 | YEATS domain containing 2 | 0.0362928 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.036251 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0359182 |
| ZNF292 | zinc finger protein 292 | 0.0356747 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0356498 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0353752 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0353624 |
| USP34 | ubiquitin specific peptidase 34 | 0.0352654 |
| SEPTIN7 | septin 7 | 0.0350966 |
| THOC2 | THO complex 2 | 0.0348527 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0346998 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0343808 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.034318 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0338567 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0337884 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.033344 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0329481 |
| RPL11 | ribosomal protein L11 | 0.0328445 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0327795 |
| RPL3 | ribosomal protein L3 | 0.0327248 |
| RPL7A | ribosomal protein L7a | 0.0324818 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0323095 |
| RBM26 | RNA binding motif protein 26 | 0.0321125 |
| XPO1 | exportin 1 | 0.0321116 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0315235 |
| RAD51B | RAD51 paralog B | 0.0314309 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0306147 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0305067 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0303008 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0299697 |
| CKAP5 | cytoskeleton associated protein 5 | 0.029892 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.029666 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0294922 |
| EFNA5 | ephrin-A5 | 0.0294551 |
| B2M | beta-2-microglobulin | 0.0292882 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0292307 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0292271 |
| CCNL1 | cyclin L1 | 0.0291177 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.256872 |
| TXNRD1 | thioredoxin reductase 1 | -0.135106 |
| LOC112694756 | uncharaterized LOC112694756 | -0.12637 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.107486 |
| TMSB10 | thymosin beta 10 | -0.0876097 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0716922 |
| ACTG1 | actin gamma 1 | -0.0706615 |
| EGR1 | early growth response 1 | -0.0663738 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0621794 |
| EMP1 | epithelial membrane protein 1 | -0.0573401 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.055693 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0523114 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0514805 |
| CD44 | CD44 molecule (Indian blood group) | -0.0513364 |
| AHNAK | AHNAK nucleoprotein | -0.051145 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0492576 |
| TP63 | tumor protein p63 | -0.04861 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0468678 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0456599 |
| HMGA1 | high mobility group AT-hook 1 | -0.0426602 |
| RIGI | RNA sensor RIG-I | -0.0413519 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0412214 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0402757 |
| OSMR | oncostatin M receptor | -0.0401401 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0384083 |
| RPL35A | ribosomal protein L35a | -0.0373178 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0369462 |
| RTN4 | reticulon 4 | -0.035997 |
| MT2A | metallothionein 2A | -0.0350588 |
| HDLBP | high density lipoprotein binding protein | -0.0347557 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.033592 |
| RGS4 | regulator of G-protein signaling 4 | -0.0328546 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.032196 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0320387 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0314398 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0311677 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0309279 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0306846 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0297729 |
| YBX3 | Y box binding protein 3 | -0.02921 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.029193 |
| FTL | ferritin, light polypeptide | -0.0286618 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0286494 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0281436 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0275049 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0266568 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.026645 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0262 |
| FUS | FUS RNA binding protein | -0.0260732 |
| APP | amyloid beta (A4) precursor protein | -0.0260598 |
| PRRC2B | proline-rich coiled-coil 2B | -0.024777 |
| ARF1 | ADP-ribosylation factor 1 | -0.0241588 |
| TAPBP | TAP binding protein (tapasin) | -0.0239998 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0235278 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0233843 |
| JUN | jun proto-oncogene | -0.0233435 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0232207 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0227767 |
| ANXA2 | annexin A2 | -0.0227429 |
| CUL1 | cullin 1 | -0.022726 |
| FBXO11 | F-box protein 11 | -0.0224521 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0224205 |
| PLSCR1 | phospholipid scramblase 1 | -0.0223315 |
| AFF4 | AF4/FMR2 family, member 4 | -0.022218 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0219152 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.021788 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0214389 |
| RHEB | Ras homolog enriched in brain | -0.0214006 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0213233 |
| CMIP | c-Maf inducing protein | -0.0212856 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0212465 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0211252 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0204701 |
| ACTN4 | actinin, alpha 4 | -0.0204458 |
| ZNF267 | zinc finger protein 267 | -0.0203486 |
| RPS24 | ribosomal protein S24 | -0.0202792 |
| SGMS2 | sphingomyelin synthase 2 | -0.020162 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0201181 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0200372 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0196564 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0196073 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0193249 |
| RPLP0 | ribosomal protein, large, P0 | -0.0192342 |
| CDK12 | cyclin-dependent kinase 12 | -0.019061 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.0190543 |
| RPS4X | ribosomal protein S4, X-linked | -0.0188643 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0187187 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0187148 |
| ZNF217 | zinc finger protein 217 | -0.0185063 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0184227 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0183958 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0182137 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0181973 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0181081 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0180438 |
| H1-0 | H1.0 linker histone | -0.0179258 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0178624 |
| ACTN1 | actinin, alpha 1 | -0.0177282 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0176509 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0174801 |
