| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glasdegib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glasdegib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.171255 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.155552 |
| FAM13A | family with sequence similarity 13, member A | 0.110644 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0940846 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0932664 |
| SMAD3 | SMAD family member 3 | 0.0809903 |
| NAV2 | neuron navigator 2 | 0.0741549 |
| NGLY1 | N-glycanase 1 | 0.0692031 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0624001 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0598847 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.058504 |
| PRELID2 | PRELI domain containing 2 | 0.0584031 |
| CDH13 | cadherin 13 | 0.0583142 |
| FLNB | filamin B, beta | 0.0559209 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0548868 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0520789 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0517975 |
| RUNX1 | runt-related transcription factor 1 | 0.0515617 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0513291 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0507344 |
| EFNA5 | ephrin-A5 | 0.050292 |
| CDCP1 | CUB domain containing protein 1 | 0.0475859 |
| ZNF638 | zinc finger protein 638 | 0.0465734 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0464931 |
| YEATS2 | YEATS domain containing 2 | 0.0456781 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0447382 |
| USP34 | ubiquitin specific peptidase 34 | 0.0439755 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0431404 |
| MEF2A | myocyte enhancer factor 2A | 0.0423125 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.041807 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0407305 |
| PFKP | phosphofructokinase, platelet | 0.0405681 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0401015 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0400863 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0398494 |
| VEGFA | vascular endothelial growth factor A | 0.0395998 |
| ZNF292 | zinc finger protein 292 | 0.0395916 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0386062 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0385008 |
| NDRG1 | N-myc downstream regulated 1 | 0.0378981 |
| PYGL | phosphorylase, glycogen, liver | 0.037838 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0377636 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0375634 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.036969 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0366693 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0361359 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0361304 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0360458 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0359559 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0357483 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0356956 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0356948 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0352256 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0348431 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0346141 |
| FAM20C | family with sequence similarity 20, member C | 0.0344596 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0337942 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0336171 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0319797 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | 0.0318559 |
| RAI1 | retinoic acid induced 1 | 0.031734 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0307205 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.030569 |
| MYO1B | myosin IB | 0.029957 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0298932 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0298089 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0296177 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0295584 |
| ATP13A3 | ATPase type 13A3 | 0.029177 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0288726 |
| ANO6 | anoctamin 6 | 0.0280551 |
| EGFR | epidermal growth factor receptor | 0.0279927 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0272826 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0272271 |
| CA12 | carbonic anhydrase XII | 0.0272086 |
| LRRC49 | leucine rich repeat containing 49 | 0.0269668 |
| OPTN | optineurin | 0.026643 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0265041 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.026191 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0259608 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0257513 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0257182 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.025718 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0253461 |
| TMEM165 | transmembrane protein 165 | 0.0251054 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0245805 |
| MTSS1 | metastasis suppressor 1 | 0.0241505 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0239945 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0238867 |
| INSIG2 | insulin induced gene 2 | 0.0238696 |
| DTNA | dystrobrevin, alpha | 0.0237888 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.023567 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0234635 |
| VEGFC | vascular endothelial growth factor C | 0.0232584 |
| ASPH | aspartate beta-hydroxylase | 0.0231826 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0231381 |
| MXI1 | MAX interactor 1, dimerization protein | 0.022946 |
| FAM219A | family with sequence similarity 219, member A | 0.0227259 |
| ANXA1 | annexin A1 | 0.022551 |
| POM121 | POM121 transmembrane nucleoporin | 0.0225417 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.251733 |
| CD44 | CD44 molecule (Indian blood group) | -0.20269 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.148426 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.145377 |
| TMSB10 | thymosin beta 10 | -0.130444 |
| FTL | ferritin, light polypeptide | -0.125658 |
| GLCCI1 | glucocorticoid induced 1 | -0.104226 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0795462 |
| RBM39 | RNA binding motif protein 39 | -0.0753679 |
| VIM | vimentin | -0.074581 |
| NTN4 | netrin 4 | -0.0739594 |
| OSMR | oncostatin M receptor | -0.0738322 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0714623 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0664271 |
| KYNU | kynureninase | -0.0635288 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0614023 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0589996 |
| FN1 | fibronectin 1 | -0.0583571 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0574617 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0553543 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0548455 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0547999 |
| LOX | lysyl oxidase | -0.0534502 |
| EGR1 | early growth response 1 | -0.0528213 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0516677 |
| RPL35A | ribosomal protein L35a | -0.0511821 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0511428 |
| RPLP1 | ribosomal protein, large, P1 | -0.0500545 |
| TNNC1 | troponin C type 1 (slow) | -0.0485577 |
| PTMA | prothymosin, alpha | -0.0481613 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0475257 |
| GPC6 | glypican 6 | -0.0471014 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0469155 |
| VCL | vinculin | -0.0468526 |
| SYAP1 | synapse associated protein 1 | -0.0462284 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0439535 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0422332 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.041812 |
| IER3 | immediate early response 3 | -0.0416964 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0406333 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0401537 |
| RPLP0 | ribosomal protein, large, P0 | -0.0394241 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0393709 |
| HDLBP | high density lipoprotein binding protein | -0.0388133 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0383987 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0375131 |
| VRK2 | vaccinia related kinase 2 | -0.037247 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0356044 |
| YBX3 | Y box binding protein 3 | -0.0350111 |
| KSR1 | kinase suppressor of ras 1 | -0.0349365 |
| RPL32 | ribosomal protein L32 | -0.034679 |
| CANX | calnexin | -0.0346383 |
| HMGA1 | high mobility group AT-hook 1 | -0.0345861 |
| RPS24 | ribosomal protein S24 | -0.0345134 |
| ANXA2 | annexin A2 | -0.0344725 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0343124 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0340489 |
| H1-0 | H1.0 linker histone | -0.033896 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0337989 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.03349 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0334459 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0331095 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0330427 |
| FBXO11 | F-box protein 11 | -0.0329344 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0327211 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0324935 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0324735 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0323979 |
| IL1R1 | interleukin 1 receptor, type I | -0.0320629 |
| VMP1 | vacuole membrane protein 1 | -0.0320531 |
| NRP1 | neuropilin 1 | -0.0320038 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0319355 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0318189 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0317644 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0316754 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.031632 |
| RPS19 | ribosomal protein S19 | -0.0312122 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0311302 |
| TMEM263 | transmembrane protein 263 | -0.0305424 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0304494 |
| S100A10 | S100 calcium binding protein A10 | -0.0303409 |
| MAP1B | microtubule-associated protein 1B | -0.0303056 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0299389 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0296106 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.029422 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0294056 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0293278 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0289693 |
| RPL34 | ribosomal protein L34 | -0.0288458 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0288157 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0287324 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0285503 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0284253 |
| HM13 | histocompatibility (minor) 13 | -0.0282111 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0280317 |
| MT2A | metallothionein 2A | -0.0278737 |
| CLIC4 | chloride intracellular channel 4 | -0.027861 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0277334 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0276693 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0269896 |
