| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glasdegib perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Glasdegib_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.158638 |
| FN1 | fibronectin 1 | 0.146388 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.141703 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.13041 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.129062 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0941781 |
| ASPH | aspartate beta-hydroxylase | 0.0887986 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0823164 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0813816 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0810377 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0775131 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0744781 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.070442 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0679991 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0653354 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0649907 |
| MSN | moesin | 0.064167 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0628139 |
| NAV2 | neuron navigator 2 | 0.0627054 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0601422 |
| SET | SET nuclear proto-oncogene | 0.0558844 |
| UPP1 | uridine phosphorylase 1 | 0.0554647 |
| SQSTM1 | sequestosome 1 | 0.0550978 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.054586 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0541221 |
| DSPP | dentin sialophosphoprotein | 0.0535674 |
| MATR3 | matrin 3 | 0.0527361 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0515807 |
| RPS6 | ribosomal protein S6 | 0.0508173 |
| RPS12 | ribosomal protein S12 | 0.0500325 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0489335 |
| RNF145 | ring finger protein 145 | 0.0473435 |
| NCKAP1 | NCK-associated protein 1 | 0.0467554 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0466857 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0458828 |
| HSPA8 | heat shock 70kDa protein 8 | 0.045763 |
| TPM3 | tropomyosin 3 | 0.0454862 |
| CCNL1 | cyclin L1 | 0.0454128 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0449706 |
| NDRG1 | N-myc downstream regulated 1 | 0.044339 |
| RPS3 | ribosomal protein S3 | 0.0443024 |
| RPL11 | ribosomal protein L11 | 0.0441458 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0441392 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0430659 |
| GOLGA4 | golgin A4 | 0.0428418 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0421912 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0419291 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0418877 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0412165 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.040387 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0401846 |
| SEPTIN7 | septin 7 | 0.0395716 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0390658 |
| RPL23 | ribosomal protein L23 | 0.0388564 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0387501 |
| TNPO1 | transportin 1 | 0.0381343 |
| RPL9 | ribosomal protein L9 | 0.0378932 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0377055 |
| TFG | TRK-fused gene | 0.0373559 |
| DTNA | dystrobrevin, alpha | 0.037114 |
| OGA | O-GlcNAcase | 0.0368762 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0368734 |
| DIAPH1 | diaphanous-related formin 1 | 0.0361629 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0359033 |
| ANXA5 | annexin A5 | 0.035793 |
| TXNRD1 | thioredoxin reductase 1 | 0.0357631 |
| PLEC | plectin | 0.035366 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.034888 |
| AHNAK | AHNAK nucleoprotein | 0.0347242 |
| TOP1 | topoisomerase (DNA) I | 0.0345629 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0340799 |
| RPL5 | ribosomal protein L5 | 0.0338727 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0336158 |
| TMSB4X | thymosin beta 4, X-linked | 0.0335474 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0334619 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0327396 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0326171 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0321698 |
| RPS17 | ribosomal protein S17 | 0.0320773 |
| CD47 | CD47 molecule | 0.0319973 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0318196 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0317371 |
| RACK1 | receptor for activated C kinase 1 | 0.0309797 |
| RPL7 | ribosomal protein L7 | 0.0306492 |
| SLMAP | sarcolemma associated protein | 0.0305583 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0305 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.030326 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0300049 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0299932 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0299869 |
| RPL14 | ribosomal protein L14 | 0.0295327 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0294709 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0291576 |
| RPL37A | ribosomal protein L37a | 0.0287205 |
| FHIT | fragile histidine triad | 0.0287068 |
| RPS3A | ribosomal protein S3A | 0.0282209 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0280993 |
| ARRDC3 | arrestin domain containing 3 | 0.0280503 |
| IRF6 | interferon regulatory factor 6 | 0.0280008 |
| HDGF | hepatoma-derived growth factor | 0.0279414 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.233436 |
| FTL | ferritin, light polypeptide | -0.16835 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.117531 |
| TMSB10 | thymosin beta 10 | -0.100155 |
| ACTG1 | actin gamma 1 | -0.0996217 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0777222 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0686758 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.058605 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.058597 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0531456 |
| HMGA1 | high mobility group AT-hook 1 | -0.0519605 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0514848 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0462938 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0451942 |
| EFNA5 | ephrin-A5 | -0.04462 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0438127 |
| RPL35A | ribosomal protein L35a | -0.043412 |
| ERBIN | erbb2 interacting protein | -0.0430194 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0413971 |
| RASAL2 | RAS protein activator like 2 | -0.0403477 |
| EXT1 | exostosin glycosyltransferase 1 | -0.038857 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0388541 |
| FBXO32 | F-box protein 32 | -0.0382733 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0371759 |
| LMO7 | LIM domain 7 | -0.0358479 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0354104 |
| TXNIP | thioredoxin interacting protein | -0.0346976 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0345617 |
| MYO1E | myosin IE | -0.0339542 |
| HLA-A | major histocompatibility complex, class I, A | -0.0334908 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.032616 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0309471 |
| DSG2 | desmoglein 2 | -0.030624 |
| VCL | vinculin | -0.0305086 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0304763 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0302506 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0302282 |
| ARF1 | ADP-ribosylation factor 1 | -0.0296178 |
| EGR1 | early growth response 1 | -0.0292673 |
| PALLD | palladin, cytoskeletal associated protein | -0.0290932 |
| UBC | ubiquitin C | -0.0290055 |
| MX2 | MX dynamin-like GTPase 2 | -0.0289677 |
| TPI1 | triosephosphate isomerase 1 | -0.0285624 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0282269 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.028107 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.028042 |
| GNAS | GNAS complex locus | -0.0278117 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0277794 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0276249 |
| FNIP1 | folliculin interacting protein 1 | -0.0276075 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0274448 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0274383 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0273248 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0271147 |
| MX1 | MX dynamin-like GTPase 1 | -0.026883 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0267312 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0265788 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0265604 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0263913 |
| MCU | mitochondrial calcium uniporter | -0.0263092 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0261743 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0261305 |
| PLSCR1 | phospholipid scramblase 1 | -0.0260513 |
| CLDN4 | claudin 4 | -0.025907 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0256573 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | -0.0254139 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0251125 |
| CD2AP | CD2-associated protein | -0.0250335 |
| EGFR | epidermal growth factor receptor | -0.0248987 |
| FBXO11 | F-box protein 11 | -0.0247678 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0247637 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0246752 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0246425 |
| KLHL24 | kelch-like family member 24 | -0.0244923 |
| LAP3 | leucine aminopeptidase 3 | -0.0243343 |
| RPL8 | ribosomal protein L8 | -0.0242878 |
| FBXO34 | F-box protein 34 | -0.0241969 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0239011 |
| RRBP1 | ribosome binding protein 1 | -0.0238715 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0237795 |
| ATOSA | atos homolog A | -0.0237565 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.023701 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0235134 |
| GOLGB1 | golgin B1 | -0.0234689 |
| GRAMD2B | GRAM domain containing 2B | -0.023133 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0230982 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0230464 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0226531 |
| NRP1 | neuropilin 1 | -0.0224846 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0224566 |
| FRMD5 | FERM domain containing 5 | -0.0222619 |
| OSMR | oncostatin M receptor | -0.022162 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0220874 |
| JMJD1C | jumonji domain containing 1C | -0.0218334 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0217572 |
| TPM4 | tropomyosin 4 | -0.0216813 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0215604 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0215214 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0214118 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0214093 |
