| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glasdegib perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glasdegib_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.204353 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.203226 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.182452 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.171863 |
| DST | dystonin | 0.148285 |
| SMYD3 | SET and MYND domain containing 3 | 0.119004 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.118776 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.113531 |
| VIM | vimentin | 0.11141 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.108884 |
| COL5A2 | collagen, type V, alpha 2 | 0.10276 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.102159 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0995199 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0988112 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0922538 |
| ZNF292 | zinc finger protein 292 | 0.0901416 |
| FN1 | fibronectin 1 | 0.0811887 |
| ASPH | aspartate beta-hydroxylase | 0.0810823 |
| TXNRD1 | thioredoxin reductase 1 | 0.0764755 |
| VMP1 | vacuole membrane protein 1 | 0.0755937 |
| USP34 | ubiquitin specific peptidase 34 | 0.0735914 |
| TFG | TRK-fused gene | 0.0735703 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0732851 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0720421 |
| MYOF | myoferlin | 0.0697215 |
| MATR3 | matrin 3 | 0.0693781 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0692097 |
| PGK1 | phosphoglycerate kinase 1 | 0.0689407 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0682979 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0682873 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0682586 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0609609 |
| AHNAK | AHNAK nucleoprotein | 0.0608358 |
| RBM39 | RNA binding motif protein 39 | 0.0600559 |
| MSN | moesin | 0.0589245 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.052136 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.052087 |
| CCNL1 | cyclin L1 | 0.0519296 |
| SBF2 | SET binding factor 2 | 0.051907 |
| DENND1A | DENN/MADD domain containing 1A | 0.0511115 |
| MSI2 | musashi RNA-binding protein 2 | 0.050666 |
| NAV2 | neuron navigator 2 | 0.0505069 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0493555 |
| SETD5 | SET domain containing 5 | 0.0472445 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0453583 |
| FAM13A | family with sequence similarity 13, member A | 0.0451022 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.044226 |
| PHF21A | PHD finger protein 21A | 0.0417731 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0412637 |
| JMJD1C | jumonji domain containing 1C | 0.0410388 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0408707 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.040625 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0404379 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0404129 |
| GPC6 | glypican 6 | 0.0401787 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0381254 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0379063 |
| RBM25 | RNA binding motif protein 25 | 0.0378384 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0366275 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0360736 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0360408 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0351409 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0350292 |
| ENO1 | enolase 1, (alpha) | 0.0349476 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0342784 |
| PKM | pyruvate kinase, muscle | 0.0334604 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0332637 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0325779 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0317061 |
| USP3 | ubiquitin specific peptidase 3 | 0.0315743 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0310473 |
| RTN4 | reticulon 4 | 0.0305095 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0303802 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0300468 |
| RUNX1 | runt-related transcription factor 1 | 0.0273794 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0266831 |
| SPAG9 | sperm associated antigen 9 | 0.0263436 |
| CDC27 | cell division cycle 27 | 0.0260459 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0254311 |
| SRPK2 | SRSF protein kinase 2 | 0.0251535 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0249432 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0248673 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0247601 |
| VCL | vinculin | 0.0241649 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0226203 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0220487 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0219121 |
| FMNL2 | formin-like 2 | 0.0216121 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0216036 |
| GOLGA4 | golgin A4 | 0.0211482 |
| COPA | coatomer protein complex, subunit alpha | 0.0194007 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0189171 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0187039 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0179529 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0175521 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0164153 |
| POTEF | POTE ankyrin domain family, member F | 0.0151417 |
| NF1 | neurofibromin 1 | 0.0149827 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0149765 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0143458 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.214914 |
| MYO1E | myosin IE | -0.154955 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.148315 |
| HMGA2 | high mobility group AT-hook 2 | -0.116499 |
| FLNB | filamin B, beta | -0.100475 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0967371 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0938378 |
| SLTM | SAFB-like, transcription modulator | -0.0883517 |
| LAMA4 | laminin, alpha 4 | -0.0848637 |
| LMO7 | LIM domain 7 | -0.0824183 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0791898 |
| LAMB3 | laminin, beta 3 | -0.0778789 |
| LAMC2 | laminin, gamma 2 | -0.0776506 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0769848 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0760719 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0759685 |
| CDK13 | cyclin-dependent kinase 13 | -0.0756435 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0740885 |
| EFNA5 | ephrin-A5 | -0.0703911 |
| FHIT | fragile histidine triad | -0.0690354 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0685153 |
| HDAC9 | histone deacetylase 9 | -0.0677771 |
| COL5A1 | collagen, type V, alpha 1 | -0.0671462 |
| RPS8 | ribosomal protein S8 | -0.0666664 |
| EGR1 | early growth response 1 | -0.0665693 |
| RPL12 | ribosomal protein L12 | -0.0650904 |
| PRKCA | protein kinase C, alpha | -0.0642145 |
| NDRG1 | N-myc downstream regulated 1 | -0.0636992 |
| TMSB10 | thymosin beta 10 | -0.0635461 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0632436 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0591756 |
| EGFR | epidermal growth factor receptor | -0.0576265 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0573507 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0572989 |
| PARD3 | par-3 family cell polarity regulator | -0.057187 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0569618 |
| YAP1 | Yes-associated protein 1 | -0.0559159 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0541509 |
| OSMR | oncostatin M receptor | -0.0538021 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0532236 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0531565 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0531243 |
| PTGES2 | prostaglandin E synthase 2 | -0.0529444 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0527694 |
| AREG | amphiregulin | -0.050686 |
| PTMA | prothymosin, alpha | -0.0498511 |
| PRELID2 | PRELI domain containing 2 | -0.048837 |
| LDHA | lactate dehydrogenase A | -0.0483287 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0480746 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0467406 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0460201 |
| ANXA2 | annexin A2 | -0.0452764 |
| RPL34 | ribosomal protein L34 | -0.0447951 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0442838 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0442046 |
| RPL37A | ribosomal protein L37a | -0.0441717 |
| RPL15 | ribosomal protein L15 | -0.0439969 |
| SLK | STE20-like kinase | -0.0436893 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0436234 |
| RPS19 | ribosomal protein S19 | -0.0436018 |
| S100A10 | S100 calcium binding protein A10 | -0.0434356 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0428999 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0428644 |
| OXR1 | oxidation resistance 1 | -0.0427253 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0423502 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0421177 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0413151 |
| CDH13 | cadherin 13 | -0.0410201 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0402969 |
| OLA1 | Obg-like ATPase 1 | -0.0385925 |
| RPS4X | ribosomal protein S4, X-linked | -0.0383226 |
| TJP1 | tight junction protein 1 | -0.0381258 |
| RPL31 | ribosomal protein L31 | -0.0380125 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0370441 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0368084 |
| FNDC3B | fibronectin type III domain containing 3B | -0.036753 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0364509 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0354388 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0351437 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.0344169 |
| NFIA | nuclear factor I/A | -0.0342875 |
| EHBP1 | EH domain binding protein 1 | -0.0341631 |
| AFDN | afadin, adherens junction formation factor | -0.0331663 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0326211 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0313133 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0303632 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0300818 |
| VEGFA | vascular endothelial growth factor A | -0.029811 |
| FNIP1 | folliculin interacting protein 1 | -0.0293261 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0291375 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0286546 |
| TPM4 | tropomyosin 4 | -0.0275975 |
| CD44 | CD44 molecule (Indian blood group) | -0.0275335 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0273073 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0269139 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0257995 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0255664 |
| RPL37 | ribosomal protein L37 | -0.0255366 |
| OGA | O-GlcNAcase | -0.0254882 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0246296 |
