| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glasdegib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glasdegib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.177804 |
| ZNF292 | zinc finger protein 292 | 0.0982713 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0976807 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0847383 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0756219 |
| RPS6 | ribosomal protein S6 | 0.0748149 |
| GOLGA4 | golgin A4 | 0.0745493 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0647754 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.06029 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0584241 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0545098 |
| PRELID2 | PRELI domain containing 2 | 0.0530073 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.052768 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0520748 |
| MYOF | myoferlin | 0.0515648 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0510724 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0509875 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0498906 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0495779 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0474457 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0472122 |
| SET | SET nuclear proto-oncogene | 0.046952 |
| NUP58 | nucleoporin 58 | 0.0464369 |
| HDAC9 | histone deacetylase 9 | 0.0460705 |
| CENPF | centromere protein F, 350/400kDa | 0.0457431 |
| FAM13A | family with sequence similarity 13, member A | 0.045507 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0443799 |
| SETD5 | SET domain containing 5 | 0.0439076 |
| PCBP2 | poly(rC) binding protein 2 | 0.0435126 |
| RPL3 | ribosomal protein L3 | 0.0434936 |
| CDC73 | cell division cycle 73 | 0.0425407 |
| ECT2 | epithelial cell transforming 2 | 0.0423301 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0423062 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0422863 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0420341 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0418059 |
| RNF145 | ring finger protein 145 | 0.0415805 |
| CCNL1 | cyclin L1 | 0.0409253 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.040722 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0401003 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0398168 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0393832 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0386511 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0386421 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0380408 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0377338 |
| XPO1 | exportin 1 | 0.0377097 |
| HELZ | helicase with zinc finger | 0.0377045 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0369595 |
| RPL21 | ribosomal protein L21 | 0.0367379 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0362776 |
| FAM168A | family with sequence similarity 168, member A | 0.0358658 |
| SRP54 | signal recognition particle 54kDa | 0.035501 |
| HDGF | hepatoma-derived growth factor | 0.0354307 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.034824 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0347866 |
| DIAPH3 | diaphanous-related formin 3 | 0.0347671 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0335365 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0334374 |
| EVI5 | ecotropic viral integration site 5 | 0.0330276 |
| COPA | coatomer protein complex, subunit alpha | 0.0329913 |
| RBM26 | RNA binding motif protein 26 | 0.0328649 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0326044 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0325028 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0323951 |
| ZNF638 | zinc finger protein 638 | 0.0323834 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0318649 |
| INSIG2 | insulin induced gene 2 | 0.0316948 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.031291 |
| SMAP1 | small ArfGAP 1 | 0.0312221 |
| CASC3 | cancer susceptibility candidate 3 | 0.0311707 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0303726 |
| RIOK3 | RIO kinase 3 | 0.0302998 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0298954 |
| MATR3 | matrin 3 | 0.0297294 |
| MKI67 | marker of proliferation Ki-67 | 0.0296877 |
| RPS3 | ribosomal protein S3 | 0.0296497 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0295111 |
| DENND4A | DENN/MADD domain containing 4A | 0.0294792 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0294234 |
| YAP1 | Yes-associated protein 1 | 0.0291787 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.029128 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0290573 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0288094 |
| B2M | beta-2-microglobulin | 0.0284985 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0284516 |
| NBAS | neuroblastoma amplified sequence | 0.028181 |
| RPL7 | ribosomal protein L7 | 0.0281732 |
| ENO1 | enolase 1, (alpha) | 0.0281614 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.028128 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0279484 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0279128 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0278144 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0277369 |
| DSTN | destrin (actin depolymerizing factor) | 0.0273686 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.027227 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0271146 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0270224 |
| RBM25 | RNA binding motif protein 25 | 0.0267401 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0267263 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.307863 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.149624 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.140294 |
| LOC112694756 | uncharaterized LOC112694756 | -0.101244 |
| AHNAK | AHNAK nucleoprotein | -0.0922854 |
| EGFR | epidermal growth factor receptor | -0.0897708 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0843014 |
| ACTG1 | actin gamma 1 | -0.0836573 |
| PKM | pyruvate kinase, muscle | -0.0834129 |
| TMSB4X | thymosin beta 4, X-linked | -0.0758619 |
| VCL | vinculin | -0.0722293 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0707833 |
| RPL35A | ribosomal protein L35a | -0.0593697 |
| RPLP0 | ribosomal protein, large, P0 | -0.0582264 |
| HDLBP | high density lipoprotein binding protein | -0.0568464 |
| LDHA | lactate dehydrogenase A | -0.0507277 |
| S100A6 | S100 calcium binding protein A6 | -0.050225 |
| TXNRD1 | thioredoxin reductase 1 | -0.0492499 |
| RTN4 | reticulon 4 | -0.0482305 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0472235 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0470407 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0460694 |
| GLI2 | GLI family zinc finger 2 | -0.0456239 |
| TJP1 | tight junction protein 1 | -0.0434907 |
| ATP9B | ATPase, class II, type 9B | -0.0430803 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0420913 |
| RPS24 | ribosomal protein S24 | -0.0419352 |
| PDGFC | platelet derived growth factor C | -0.0419289 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0412366 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0410786 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0409982 |
| EFNA5 | ephrin-A5 | -0.0396752 |
| OSMR | oncostatin M receptor | -0.0383411 |
| ZNF217 | zinc finger protein 217 | -0.0359322 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.03593 |
| CCND1 | cyclin D1 | -0.0352493 |
| RPL4 | ribosomal protein L4 | -0.0336478 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0328274 |
| SGMS1 | sphingomyelin synthase 1 | -0.0326025 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0318073 |
| S100A10 | S100 calcium binding protein A10 | -0.0313487 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0309861 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0308248 |
| RPL34 | ribosomal protein L34 | -0.0300294 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0297838 |
| ANK2 | ankyrin 2, neuronal | -0.0288328 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0285722 |
| DUSP4 | dual specificity phosphatase 4 | -0.0285351 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0269655 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0268608 |
| S100A4 | S100 calcium binding protein A4 | -0.0266736 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0260402 |
| ZNF608 | zinc finger protein 608 | -0.0256506 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0253318 |
| FLNB | filamin B, beta | -0.0245941 |
| HMGA1 | high mobility group AT-hook 1 | -0.0239983 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0235793 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0232667 |
| GLI3 | GLI family zinc finger 3 | -0.0230571 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0229278 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0228674 |
| FOXP1 | forkhead box P1 | -0.0227351 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.022667 |
| HLA-B | major histocompatibility complex, class I, B | -0.0225604 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0225062 |
| SP100 | SP100 nuclear antigen | -0.0224603 |
| TMSB10 | thymosin beta 10 | -0.0223323 |
| RPL13A | ribosomal protein L13a | -0.0223021 |
| RPS4X | ribosomal protein S4, X-linked | -0.0222176 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0220505 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0219545 |
| RIGI | RNA sensor RIG-I | -0.0218668 |
| RPLP1 | ribosomal protein, large, P1 | -0.0217513 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0217303 |
| RHOB | ras homolog family member B | -0.0217227 |
| GNAS | GNAS complex locus | -0.021704 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0217029 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0214937 |
| CEP95 | centrosomal protein 95kDa | -0.0213724 |
| FUS | FUS RNA binding protein | -0.0213544 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0212849 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.0212721 |
| RPS27A | ribosomal protein S27a | -0.0211106 |
| SDCBP | syndecan binding protein (syntenin) | -0.0206377 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0205475 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0205297 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0204546 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0202175 |
| NF1 | neurofibromin 1 | -0.0201674 |
| TKT | transketolase | -0.0198819 |
| RPS23 | ribosomal protein S23 | -0.0198441 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0198035 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0195863 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0195589 |
| PLSCR1 | phospholipid scramblase 1 | -0.0195588 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0195466 |
| ARF1 | ADP-ribosylation factor 1 | -0.0193272 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0191996 |
| RPS19 | ribosomal protein S19 | -0.0191651 |
| THBD | thrombomodulin | -0.0187645 |
