| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glasdegib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glasdegib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.237885 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.154621 |
| ZNF292 | zinc finger protein 292 | 0.11211 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.104428 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0998432 |
| B2M | beta-2-microglobulin | 0.0791774 |
| COL1A2 | collagen, type I, alpha 2 | 0.0721668 |
| ATP13A3 | ATPase type 13A3 | 0.0653252 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0624507 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0611467 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0607419 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0577959 |
| PGK1 | phosphoglycerate kinase 1 | 0.0572637 |
| ENO1 | enolase 1, (alpha) | 0.0572401 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0561884 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0547073 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0531706 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0531258 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0525596 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0525588 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0521731 |
| TNS3 | tensin 3 | 0.0519832 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0515825 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0514885 |
| LOX | lysyl oxidase | 0.0497316 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0497148 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0480673 |
| FNDC3B | fibronectin type III domain containing 3B | 0.04803 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0477694 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0475657 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0468911 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0460675 |
| NEK7 | NIMA-related kinase 7 | 0.0440364 |
| VCAN | versican | 0.0433348 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0419005 |
| TMF1 | TATA element modulatory factor 1 | 0.0418616 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0416541 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0411673 |
| MYOF | myoferlin | 0.0409836 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0403449 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0403388 |
| MAP4 | microtubule-associated protein 4 | 0.0401145 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0397788 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.039625 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0384053 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0380153 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0376632 |
| OXR1 | oxidation resistance 1 | 0.0373695 |
| PRRX1 | paired related homeobox 1 | 0.0373226 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0367653 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0365112 |
| RBM25 | RNA binding motif protein 25 | 0.0358674 |
| ANXA1 | annexin A1 | 0.035865 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0354263 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0351166 |
| FLNB | filamin B, beta | 0.0345821 |
| IMMT | inner membrane protein, mitochondrial | 0.0345388 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0343184 |
| RAI14 | retinoic acid induced 14 | 0.0341705 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0340577 |
| TPM4 | tropomyosin 4 | 0.0337956 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0337541 |
| MTMR3 | myotubularin related protein 3 | 0.033661 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0332823 |
| FAM13A | family with sequence similarity 13, member A | 0.0332661 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0331189 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0329876 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0329253 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0325564 |
| MORF4L2 | mortality factor 4 like 2 | 0.0323889 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0322267 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0320676 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.031646 |
| MYLK | myosin light chain kinase | 0.0315092 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0312814 |
| ZFR | zinc finger RNA binding protein | 0.0310787 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0309981 |
| TPM1 | tropomyosin 1 (alpha) | 0.0308817 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0305628 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0304928 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0303092 |
| CDC73 | cell division cycle 73 | 0.0302619 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0302468 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0302267 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0302056 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0301813 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0299565 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0298962 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0298959 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0298602 |
| MTPN | myotrophin | 0.0297038 |
| ETV6 | ets variant 6 | 0.029642 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0295582 |
| TNRC6A | trinucleotide repeat containing 6A | 0.029438 |
| USP33 | ubiquitin specific peptidase 33 | 0.02927 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0291693 |
| THOC2 | THO complex 2 | 0.0291267 |
| MEIS1 | Meis homeobox 1 | 0.0290906 |
| FRMD6 | FERM domain containing 6 | 0.0290198 |
| MTF2 | metal response element binding transcription factor 2 | 0.0289514 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.26773 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.158227 |
| TMSB10 | thymosin beta 10 | -0.112802 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0888724 |
| FTL | ferritin, light polypeptide | -0.0862291 |
| PKM | pyruvate kinase, muscle | -0.0764874 |
| VIM | vimentin | -0.0748897 |
| POTEF | POTE ankyrin domain family, member F | -0.0724403 |
| HLA-B | major histocompatibility complex, class I, B | -0.0659626 |
| LMNA | lamin A/C | -0.0508866 |
| EGFR | epidermal growth factor receptor | -0.0474166 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0460411 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0453851 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0447573 |
| C1D | C1D nuclear receptor corepressor | -0.0440849 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0430297 |
| UBC | ubiquitin C | -0.0416519 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0410389 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0400132 |
| ERBIN | erbb2 interacting protein | -0.0395825 |
| CANX | calnexin | -0.038705 |
| MSN | moesin | -0.0379896 |
| HLA-C | major histocompatibility complex, class I, C | -0.0376717 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0365767 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0365763 |
| CLIC4 | chloride intracellular channel 4 | -0.0359207 |
| MYADM | myeloid-associated differentiation marker | -0.0355092 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0352078 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0351207 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0350126 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0347369 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0346615 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0343891 |
| PTGES2 | prostaglandin E synthase 2 | -0.0343363 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0342324 |
| JMJD1C | jumonji domain containing 1C | -0.0334235 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0329906 |
| TBCA | tubulin folding cofactor A | -0.0328069 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.032675 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0325676 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0324934 |
| S100A6 | S100 calcium binding protein A6 | -0.0324674 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0320327 |
| FN1 | fibronectin 1 | -0.0317703 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0317012 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0312719 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0312463 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.0310714 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0308778 |
| ACTG1 | actin gamma 1 | -0.0306887 |
| S100A10 | S100 calcium binding protein A10 | -0.0299955 |
| SMYD3 | SET and MYND domain containing 3 | -0.0299422 |
| RGS17 | regulator of G-protein signaling 17 | -0.0298332 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.029355 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0293148 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0291118 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0289369 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0288362 |
| ITGAV | integrin, alpha V | -0.0288034 |
| CD44 | CD44 molecule (Indian blood group) | -0.0279851 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0279104 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0278902 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.0276755 |
| RPLP1 | ribosomal protein, large, P1 | -0.0272352 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0269886 |
| COG6 | component of oligomeric golgi complex 6 | -0.0269792 |
| PKP4 | plakophilin 4 | -0.0269107 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0267931 |
| AFTPH | aftiphilin | -0.0267698 |
| CLTC | clathrin, heavy chain (Hc) | -0.0264962 |
| RTN4 | reticulon 4 | -0.0263995 |
| URI1 | URI1, prefoldin-like chaperone | -0.0261853 |
| TGFB1 | transforming growth factor, beta 1 | -0.0259712 |
| RAB31 | RAB31, member RAS oncogene family | -0.0258086 |
| DTNA | dystrobrevin, alpha | -0.0255394 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0254801 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0254655 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0254616 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0253442 |
| SDC4 | syndecan 4 | -0.0252443 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0250267 |
| NUP214 | nucleoporin 214kDa | -0.0249569 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0248678 |
| RC3H1 | ring finger and CCCH-type domains 1 | -0.0247207 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0247116 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0246781 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0245973 |
| SEPTIN2 | septin 2 | -0.0245692 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0245227 |
| FMNL2 | formin-like 2 | -0.0244828 |
| RASA3 | RAS p21 protein activator 3 | -0.0244742 |
| SCFD2 | sec1 family domain containing 2 | -0.0243857 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0243132 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0243109 |
| HM13 | histocompatibility (minor) 13 | -0.0242886 |
| RPL23 | ribosomal protein L23 | -0.0242669 |
| RPL36A | ribosomal protein L36a | -0.0241384 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0238837 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0238322 |
| IRF1 | interferon regulatory factor 1 | -0.0237548 |
