| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glasdegib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glasdegib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.214355 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0888408 |
| TMEM156 | transmembrane protein 156 | 0.0863633 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0761261 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0746901 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0728959 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.071392 |
| ITGA1 | integrin, alpha 1 | 0.0634 |
| SMAD3 | SMAD family member 3 | 0.0623692 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0619311 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0608937 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0600007 |
| OGA | O-GlcNAcase | 0.0590866 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0556574 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0491237 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0470065 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0449831 |
| GOLGA4 | golgin A4 | 0.0448504 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0436159 |
| ZNF292 | zinc finger protein 292 | 0.0423952 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0421904 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0412537 |
| WDR26 | WD repeat domain 26 | 0.0411459 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0407816 |
| NUP58 | nucleoporin 58 | 0.0402075 |
| CDCP1 | CUB domain containing protein 1 | 0.039934 |
| CD109 | CD109 molecule | 0.038844 |
| FAM13A | family with sequence similarity 13, member A | 0.0386913 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0376533 |
| FNBP1 | formin binding protein 1 | 0.0369144 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0369051 |
| PTK2 | protein tyrosine kinase 2 | 0.0363491 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0352484 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0351305 |
| CENPF | centromere protein F, 350/400kDa | 0.0344854 |
| ETNK1 | ethanolamine kinase 1 | 0.0343112 |
| MT2A | metallothionein 2A | 0.033668 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0331335 |
| SUCO | SUN domain containing ossification factor | 0.0321462 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0316889 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0308538 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.030764 |
| AHR | aryl hydrocarbon receptor | 0.030519 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0304298 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.0301975 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0298424 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0294712 |
| TMEM165 | transmembrane protein 165 | 0.0294155 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0293785 |
| WDR45B | WD repeat domain 45B | 0.0291757 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0290078 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0287899 |
| TXNRD1 | thioredoxin reductase 1 | 0.0287832 |
| RPS6 | ribosomal protein S6 | 0.0283508 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0277544 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0275821 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0275813 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0274666 |
| INSIG2 | insulin induced gene 2 | 0.027455 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0270249 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0269705 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0268629 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0267517 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0264926 |
| KLHL5 | kelch-like family member 5 | 0.0262836 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0260175 |
| AFDN | afadin, adherens junction formation factor | 0.0259384 |
| MKI67 | marker of proliferation Ki-67 | 0.0258532 |
| CDC27 | cell division cycle 27 | 0.0255998 |
| PELO | pelota homolog (Drosophila) | 0.0255205 |
| CAB39 | calcium binding protein 39 | 0.0252145 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0250905 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0249608 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.024898 |
| EREG | epiregulin | 0.0246631 |
| ATP13A3 | ATPase type 13A3 | 0.0245215 |
| FAT1 | FAT atypical cadherin 1 | 0.0244191 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0242832 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0242009 |
| FRYL | FRY-like | 0.0241956 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0240518 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0236469 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0234574 |
| COG5 | component of oligomeric golgi complex 5 | 0.023331 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0232892 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.023135 |
| CDC73 | cell division cycle 73 | 0.0229616 |
| ANXA5 | annexin A5 | 0.022943 |
| RNF145 | ring finger protein 145 | 0.0229273 |
| SLTM | SAFB-like, transcription modulator | 0.0228583 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0228499 |
| RO60 | Ro60, Y RNA binding protein | 0.0228284 |
| CD44 | CD44 molecule (Indian blood group) | 0.0227985 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0226811 |
| ERBIN | erbb2 interacting protein | 0.0226558 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.022633 |
| SNX9 | sorting nexin 9 | 0.0225811 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0225789 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0222251 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0221707 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.262228 |
| FN1 | fibronectin 1 | -0.216655 |
| NRG1 | neuregulin 1 | -0.208043 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.108609 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0812503 |
| VCL | vinculin | -0.0755669 |
| FTL | ferritin, light polypeptide | -0.0677557 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0653479 |
| HLA-B | major histocompatibility complex, class I, B | -0.0529859 |
| TMSB10 | thymosin beta 10 | -0.0473515 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0465637 |
| AEBP2 | AE binding protein 2 | -0.0439456 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0429815 |
| INTS6 | integrator complex subunit 6 | -0.0421808 |
| PALLD | palladin, cytoskeletal associated protein | -0.0405147 |
| SQSTM1 | sequestosome 1 | -0.0381821 |
| LMNA | lamin A/C | -0.0381741 |
| SYT1 | synaptotagmin I | -0.036996 |
| TXNIP | thioredoxin interacting protein | -0.0361896 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0361849 |
| EGR1 | early growth response 1 | -0.0351656 |
| NTN4 | netrin 4 | -0.0342113 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0341363 |
| PLIN2 | perilipin 2 | -0.0337563 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0320225 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0319333 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0317552 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0313128 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0306977 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0305656 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0304599 |
| SFTPA2 | surfactant protein A2 | -0.0303504 |
| S100A6 | S100 calcium binding protein A6 | -0.0301067 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0297194 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0288917 |
| PTMA | prothymosin, alpha | -0.0267576 |
| B2M | beta-2-microglobulin | -0.0267539 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.026271 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.026202 |
| LRRC23 | leucine rich repeat containing 23 | -0.0260474 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0258265 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0250457 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0245474 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0243262 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0241196 |
| HLA-A | major histocompatibility complex, class I, A | -0.0237127 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0234805 |
| RAI14 | retinoic acid induced 14 | -0.0234276 |
| ACTG1 | actin gamma 1 | -0.0232825 |
| GLUL | glutamate-ammonia ligase | -0.0232609 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0230167 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0226204 |
| GPC6 | glypican 6 | -0.0225338 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0224865 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0221539 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0221141 |
| GLIS3 | GLIS family zinc finger 3 | -0.0220189 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0219655 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0219213 |
| MCL1 | myeloid cell leukemia 1 | -0.0218638 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0216565 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0214803 |
| LOX | lysyl oxidase | -0.0214774 |
| CTSD | cathepsin D | -0.0211014 |
| TENM4 | teneurin transmembrane protein 4 | -0.0210664 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0208451 |
| GNAS | GNAS complex locus | -0.0208049 |
| TPI1 | triosephosphate isomerase 1 | -0.0205354 |
| CALR | calreticulin | -0.0205218 |
| TUFT1 | tuftelin 1 | -0.0203621 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0203405 |
| HMGA2 | high mobility group AT-hook 2 | -0.0202905 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0201478 |
| MAP1B | microtubule-associated protein 1B | -0.0199995 |
| RAB10 | RAB10, member RAS oncogene family | -0.0197278 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0195445 |
| UBC | ubiquitin C | -0.0194992 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0193789 |
| FBXO11 | F-box protein 11 | -0.0193643 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0191138 |
| KSR1 | kinase suppressor of ras 1 | -0.0189404 |
| RASAL2 | RAS protein activator like 2 | -0.0188267 |
| ADIPOR2 | adiponectin receptor 2 | -0.0187679 |
| CLIC4 | chloride intracellular channel 4 | -0.0186018 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0183481 |
| CCDC138 | coiled-coil domain containing 138 | -0.0182359 |
| TNNC1 | troponin C type 1 (slow) | -0.0181595 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0177746 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0176666 |
| RND3 | Rho family GTPase 3 | -0.0176231 |
| ARF1 | ADP-ribosylation factor 1 | -0.0172607 |
| MYO1E | myosin IE | -0.017103 |
| CTSB | cathepsin B | -0.0170412 |
| ASPH | aspartate beta-hydroxylase | -0.0170367 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0169578 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.016936 |
| ABR | active BCR-related | -0.0167011 |
| TMSB4X | thymosin beta 4, X-linked | -0.0166968 |
| JUN | jun proto-oncogene | -0.0165591 |
| RIGI | RNA sensor RIG-I | -0.016492 |
