Gliosis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description The presence of gliosis in the central nervous system. (Human Phenotype Ontology, HP_0002171)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D005911
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Genes

140 genes/proteins associated with the disease Gliosis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ITGA1 integrin, alpha 1 2.88009
ITGB4 integrin, beta 4 2.88009
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 2.88009
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 2.88009
BDNF brain-derived neurotrophic factor 2.88009
MAPK3 mitogen-activated protein kinase 3 2.88009
MAPK1 mitogen-activated protein kinase 1 2.88009
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.88009
FGF2 fibroblast growth factor 2 (basic) 2.88009
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.88009
TNR tenascin R 2.88009
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.88009
GRM8 glutamate receptor, metabotropic 8 2.88009
GFAP glial fibrillary acidic protein 2.88009
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 2.88009
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.88009
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.73332
ACO2 aconitase 2, mitochondrial 1.60874
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.58654
FOS FBJ murine osteosarcoma viral oncogene homolog 1.54669
BCL2 B-cell CLL/lymphoma 2 1.51456
IFNG interferon, gamma 1.4727
TNF tumor necrosis factor 1.46041
NOS1 nitric oxide synthase 1 (neuronal) 1.44572
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.44029
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.4313
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.42211
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.40787
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.40595
IL1B interleukin 1, beta 1.40092
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.3973
HMOX1 heme oxygenase 1 1.3878
TH tyrosine hydroxylase 1.37789
NOS2 nitric oxide synthase 2, inducible 1.37446
BAX BCL2-associated X protein 1.37418
EGR1 early growth response 1 1.36677
IL6 interleukin 6 1.36677
DRD2 dopamine receptor D2 1.35098
MAPT microtubule-associated protein tau 1.34983
CCL2 chemokine (C-C motif) ligand 2 1.34256
GAP43 growth associated protein 43 1.34169
DDIT3 DNA-damage-inducible transcript 3 1.34024
PRKCD protein kinase C, delta 1.32667
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.31927
ACHE acetylcholinesterase (Yt blood group) 1.31837
GSK3B glycogen synthase kinase 3 beta 1.31119
NAMPT nicotinamide phosphoribosyltransferase 1.3085
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.30666
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.30604
TP53 tumor protein p53 1.30482
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.30451
VEGFA vascular endothelial growth factor A 1.30208
SOD2 superoxide dismutase 2, mitochondrial 1.29225
BMP4 bone morphogenetic protein 4 1.28827
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.28149
CAT catalase 1.28119
PARK2 parkin RBR E3 ubiquitin protein ligase 1.28119
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.28088
PRKCE protein kinase C, epsilon 1.26205
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.25214
NFE2L2 nuclear factor, erythroid 2-like 2 1.24997
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 1.24655
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.24338
RGS4 regulator of G-protein signaling 4 1.22534
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.21919
PRKCZ protein kinase C, zeta 1.21501
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.20493
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.19999
GDNF glial cell derived neurotrophic factor 1.19999
ACO1 aconitase 1, soluble 1.1977
SIRT2 sirtuin 2 1.19542
MCM4 minichromosome maintenance complex component 4 1.19047
JUN jun proto-oncogene 1.18816
LEP leptin 1.17893
PLCE1 phospholipase C, epsilon 1 1.17333
NOG noggin 1.173
HEPH hephaestin 1.173
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 1.165
ADORA2A adenosine A2a receptor 1.16401
SOD1 superoxide dismutase 1, soluble 1.15695
IL10 interleukin 10 1.15055
HSPA8 heat shock 70kDa protein 8 1.14747
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.14575
MBP myelin basic protein 1.1437
PCDH7 protocadherin 7 1.142
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.13586
CYCS cytochrome c, somatic 1.13075
PRDX2 peroxiredoxin 2 1.12838
PRNP prion protein 1.12461
S100A9 S100 calcium binding protein A9 1.12461
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.12185
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.12117
UNC13C unc-13 homolog C (C. elegans) 1.11945
CXCL11 chemokine (C-X-C motif) ligand 11 1.11775
DUSP1 dual specificity phosphatase 1 1.11606
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.11571
TPCN1 two pore segment channel 1 1.11151
RGS2 regulator of G-protein signaling 2 1.11046
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.11046
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.10493
PPARG peroxisome proliferator-activated receptor gamma 1.10388
SCAND1 SCAN domain containing 1 1.10388
CXCL10 chemokine (C-X-C motif) ligand 10 1.10175
SFTPB surfactant protein B 1.09857
IGF1 insulin-like growth factor 1 (somatomedin C) 1.09751
TEK TEK tyrosine kinase, endothelial 1.09576
PRL prolactin 1.08797
RRM2 ribonucleotide reductase M2 1.0869
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.08513
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.08407
CCNB2 cyclin B2 1.08372
NFIB nuclear factor I/B 1.08126
CDK2 cyclin-dependent kinase 2 1.07875
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.06771
CCND1 cyclin D1 1.06442
ENO1 enolase 1, (alpha) 1.06225
MAPK8 mitogen-activated protein kinase 8 1.06152
CREB1 cAMP responsive element binding protein 1 1.05936
RNF145 ring finger protein 145 1.04794
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.04427
CXCL2 chemokine (C-X-C motif) ligand 2 1.03789
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 1.03715
CD68 CD68 molecule 1.03419
ALDOC aldolase C, fructose-bisphosphate 1.03419
CD86 CD86 molecule 1.03235
ALPP alkaline phosphatase, placental 1.03197
LZTFL1 leucine zipper transcription factor-like 1 1.03084
PTK2B protein tyrosine kinase 2 beta 1.03009
F2 coagulation factor II (thrombin) 1.02671
AP3B2 adaptor-related protein complex 3, beta 2 subunit 1.02373
GSTP1 glutathione S-transferase pi 1 1.02225
GADD45A growth arrest and DNA-damage-inducible, alpha 1.02188
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.02151
PDYN prodynorphin 1.01852
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.01814
MT2A metallothionein 2A 1.01776
ICAM1 intercellular adhesion molecule 1 1.01437
ENO2 enolase 2 (gamma, neuronal) 1.01399
ELF1 E74-like factor 1 (ets domain transcription factor) 1.01249
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.01137