Globoid Cell Leukodystrophy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0023521
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Genes

34 genes associated with the disease Globoid Cell Leukodystrophy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
ANGPT2 angiopoietin 2
ARSA arylsulfatase A
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
BECN1 beclin 1, autophagy related
CASP3 caspase 3, apoptosis-related cysteine peptidase
CHIT1 chitinase 1 (chitotriosidase)
COL4A1 collagen, type IV, alpha 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DEGS1 delta(4)-desaturase, sphingolipid 1
EBP emopamil binding protein (sterol isomerase)
GALC galactosylceramidase
GCA grancalcin, EF-hand calcium binding protein
GCLC glutamate-cysteine ligase, catalytic subunit
GLB1 galactosidase, beta 1
GMCL1 germ cell-less, spermatogenesis associated 1
GMCL1P1 germ cell-less, spermatogenesis associated 1 pseudogene 1
IDUA iduronidase, alpha-L-
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2R insulin-like growth factor 2 receptor
LAMC2 laminin, gamma 2
LAMP1 lysosomal-associated membrane protein 1
NFE2L2 nuclear factor, erythroid 2-like 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
PLA2G1B phospholipase A2, group IB (pancreas)
PLB1 phospholipase B1
PSAP prosaposin
RNF139 ring finger protein 139
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TP53 tumor protein p53
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta