Glomerulonephritis Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A nephritis that causes inflammation of the glomeruli located_in kidney. (Human Disease Ontology, DOID_2921)
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Genes

219 genes associated with the disease Glomerulonephritis in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
LY75 lymphocyte antigen 75 2.055
ITGB6 integrin, beta 6 2.055
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.055
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.049
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.049
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.046
POU5F1 POU class 5 homeobox 1 2.046
CCHCR1 coiled-coil alpha-helical rod protein 1 2.046
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.046
TCF19 transcription factor 19 2.046
C6ORF15 chromosome 6 open reading frame 15 2.046
GPSM3 G-protein signaling modulator 3 2.043
NOTCH4 notch 4 2.043
TNXB tenascin XB 2.042
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 2.042
BTNL2 butyrophilin-like 2 2.041
TSBP1 testis expressed basic protein 1 2.041
MUC22 mucin 22 2.039
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 2.037
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2.037
DEFA3 defensin, alpha 3, neutrophil-specific 2.027
DEFA1 defensin, alpha 1 2.027
DEFA1B defensin, alpha 1B 2.027
SLC44A4 solute carrier family 44, member 4 2.021
ZBTB12 zinc finger and BTB domain containing 12 2.021
C4A complement component 4A (Rodgers blood group) 2.021
C2 complement component 2 2.021
CFB complement factor B 2.021
STK19 serine/threonine kinase 19 2.021
EHMT2 euchromatic histone-lysine N-methyltransferase 2 2.021
NELFE negative elongation factor complex member E 2.021
DXO decapping exoribonuclease 2.021
C6ORF47 chromosome 6 open reading frame 47 2.017
TNF tumor necrosis factor 2.017
LY6G6F lymphocyte antigen 6 complex, locus G6F 2.017
CSNK2B casein kinase 2, beta polypeptide 2.017
GPANK1 G patch domain and ankyrin repeats 1 2.017
APOM apolipoprotein M 2.017
DDAH2 dimethylarginine dimethylaminohydrolase 2 2.017
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.017
LY6G5B lymphocyte antigen 6 complex, locus G5B 2.017
PRRC2A proline-rich coiled-coil 2A 2.017
BAG6 BCL2-associated athanogene 6 2.017
LTA lymphotoxin alpha 2.017
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.017
LY6G6D lymphocyte antigen 6 complex, locus G6D 2.017
LTB lymphotoxin beta (TNF superfamily, member 3) 2.017
CLIC1 chloride intracellular channel 1 2.017
LST1 leukocyte specific transcript 1 2.017
NCR3 natural cytotoxicity triggering receptor 3 2.017
DEFA5 defensin, alpha 5, Paneth cell-specific 2.017
LY6G5C lymphocyte antigen 6 complex, locus G5C 2.017
AIF1 allograft inflammatory factor 1 2.017
ABHD16A abhydrolase domain containing 16A 2.017
DEFB1 defensin, beta 1 2.014
DEFA4 defensin, alpha 4, corticostatin 2.014
DEFA6 defensin, alpha 6, Paneth cell-specific 2.014
HLA-DRA major histocompatibility complex, class II, DR alpha 2.01
EGFL8 EGF-like-domain, multiple 8 2.009
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 2.009
PBX2 pre-B-cell leukemia homeobox 2 2.009
FKBPL FK506 binding protein like 2.009
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 2.009
PPT2 palmitoyl-protein thioesterase 2 2.009
PRRT1 proline-rich transmembrane protein 1 2.009
ATF6B activating transcription factor 6 beta 2.009
AGER advanced glycosylation end product-specific receptor 2.009
SLC39A8 solute carrier family 39 (zinc transporter), member 8 1.969
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.969
MANBA mannosidase, beta A, lysosomal 1.969
HLA-C major histocompatibility complex, class I, C 1.968
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 1.954
C4B complement component 4B (Chido blood group) 1.954
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.95
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.95
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1.95
ITGAD integrin, alpha D 1.95
ZNF843 zinc finger protein 843 1.95
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 1.947
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 1.947
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 1.947
MSH5 mutS homolog 5 1.946
SAPCD1 suppressor APC domain containing 1 1.946
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 1.946
MET MET proto-oncogene, receptor tyrosine kinase 1.946
VARS1 valyl-tRNA synthetase 1 1.935
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.935
HSPA1B heat shock 70kDa protein 1B 1.935
HSPA1A heat shock 70kDa protein 1A 1.935
HSPA1L heat shock 70kDa protein 1-like 1.935
NEU1 sialidase 1 (lysosomal sialidase) 1.935
HLA-DOB major histocompatibility complex, class II, DO beta 1.93
MUC21 mucin 21, cell surface associated 1.922
DDR1 discoidin domain receptor tyrosine kinase 1 1.922
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 1.922
VARS2 valyl-tRNA synthetase 2, mitochondrial 1.922
SFTA2 surfactant associated 2 1.922
MUCL3 mucin like 3 1.922
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.831
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.831
COL11A2 collagen, type XI, alpha 2 1.831
HORMAD2 HORMA domain containing 2 1.788
MTMR3 myotubularin related protein 3 1.788
KCNT2 potassium channel, sodium activated subfamily T, member 2 1.775
CFHR3 complement factor H-related 3 1.775
CFH complement factor H 1.775
HLA-DOA major histocompatibility complex, class II, DO alpha 1.621
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 1.609
SAT2 spermidine/spermine N1-acetyltransferase family member 2 1.609
CD68 CD68 molecule 1.609
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 1.609
SOX15 SRY (sex determining region Y)-box 15 1.609
FXR2 fragile X mental retardation, autosomal homolog 2 1.609
EIF4A1 eukaryotic translation initiation factor 4A1 1.609
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 1.609
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 1.609
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 1.609
SHBG sex hormone-binding globulin 1.609
MPDU1 mannose-P-dolichol utilization defect 1 1.609
CFL1 cofilin 1 (non-muscle) 1.487
SNX32 sorting nexin 32 1.487
AP5B1 adaptor-related protein complex 5, beta 1 subunit 1.487
RNASEH2C ribonuclease H2, subunit C 1.487
MUS81 MUS81 structure-specific endonuclease subunit 1.487
KAT5 K(lysine) acetyltransferase 5 1.487
CTSW cathepsin W 1.487
OVOL1 ovo-like zinc finger 1 1.487
FIBP fibroblast growth factor (acidic) intracellular binding protein 1.487
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.487
RXRB retinoid X receptor, beta 1.46
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 1.46
RING1 ring finger protein 1 1.46
SLC39A7 solute carrier family 39 (zinc transporter), member 7 1.46
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 1.451
PMPCA peptidase (mitochondrial processing) alpha 1.451
SEC16A SEC16 homolog A (S. cerevisiae) 1.451
CARD9 caspase recruitment domain family, member 9 1.451
DNLZ DNL-type zinc finger 1.451
ENTR1 endosome associated trafficking regulator 1 1.451
GPSM1 G-protein signaling modulator 1 1.451
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 1.451
CCDC187 coiled-coil domain containing 187 1.451
DUSP22 dual specificity phosphatase 22 1.426
TXNL4B thioredoxin-like 4B 1.409
DHODH dihydroorotate dehydrogenase (quinone) 1.409
HPR haptoglobin-related protein 1.409
HP haptoglobin 1.409
ATXN1L ataxin 1-like 1.409
PKD1L3 polycystic kidney disease 1-like 3 1.409
ZNF821 zinc finger protein 821 1.409
IST1 increased sodium tolerance 1 homolog (yeast) 1.409
SLC35G6 solute carrier family 35, member G6 1.398
ZBTB4 zinc finger and BTB domain containing 4 1.398
HLA-B major histocompatibility complex, class I, B 1.346
BRD2 bromodomain containing 2 1.326
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.326
HLA-DMA major histocompatibility complex, class II, DM alpha 1.326
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.326
HLA-DMB major histocompatibility complex, class II, DM beta 1.326
WRAP53 WD repeat containing, antisense to TP53 1.319
TP53 tumor protein p53 1.319
POLR1C polymerase (RNA) I polypeptide C, 30kDa 1.3
MRPS18A mitochondrial ribosomal protein S18A 1.3
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 1.296
CD28 CD28 molecule 1.296
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 1.268
RPL39L ribosomal protein L39-like 1.268
LYN LYN proto-oncogene, Src family tyrosine kinase 1.261
XKR5 XK, Kell blood group complex subunit-related family, member 5 1.252
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 1.252
ODF1 outer dense fiber of sperm tails 1 1.246
ZCCHC24 zinc finger, CCHC domain containing 24 1.238
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.238
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.238
PPIF peptidylprolyl isomerase F 1.238
ZMIZ1 zinc finger, MIZ-type containing 1 1.238
FCRL4 Fc receptor-like 4 1.189
EXT2 exostosin glycosyltransferase 2 1.169
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 1.169
ACCSL 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like 1.169
VAV3 vav 3 guanine nucleotide exchange factor 1.146
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 1.143
TCF3 transcription factor 3 1.143
PLK5 polo-like kinase 5 1.143
ADAMTSL5 ADAMTS-like 5 1.143
MEX3D mex-3 RNA binding family member D 1.143
MBD3 methyl-CpG binding domain protein 3 1.143
PUS10 pseudouridylate synthase 10 1.101
RREB1 ras responsive element binding protein 1 1.101
PAPOLG poly(A) polymerase gamma 1.101
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.101
SSR1 signal sequence receptor, alpha 1.101
MPRIP myosin phosphatase Rho interacting protein 1.041
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.041
REEP3 receptor accessory protein 3 1.024
JMJD1C jumonji domain containing 1C 1.024
NLRP2 NLR family, pyrin domain containing 2 1.012
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 1.012
FCAR Fc fragment of IgA receptor 1.012
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 1.012
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 1.012
NCR1 natural cytotoxicity triggering receptor 1 1.012
NLRP7 NLR family, pyrin domain containing 7 1.012
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 0.988
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.988
IRF4 interferon regulatory factor 4 0.938
CCR6 chemokine (C-C motif) receptor 6 0.865
RNASET2 ribonuclease T2 0.865
RNF39 ring finger protein 39 0.819
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 0.819
HLA-A major histocompatibility complex, class I, A 0.819
FCRL5 Fc receptor-like 5 0.582
FCRL2 Fc receptor-like 2 0.572
FCRL3 Fc receptor-like 3 0.572
IRF8 interferon regulatory factor 8 0.52
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.505
PF4V1 platelet factor 4 variant 1 0.504
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.504
CXCL6 chemokine (C-X-C motif) ligand 6 0.504