Glomerulonephritis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A nephritis that causes inflammation of the glomeruli located_in kidney. (Human Disease Ontology, DOID_2921)
External Link https://www.disgenet.org/browser/0/1/0/C0017658
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Genes

377 genes associated with the disease Glomerulonephritis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ACE angiotensin I converting enzyme
ACKR2 atypical chemokine receptor 2
ACR acrosin
ACTN4 actinin, alpha 4
ADAM10 ADAM metallopeptidase domain 10
ADM adrenomedullin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHCY adenosylhomocysteinase
AIF1 allograft inflammatory factor 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALB albumin
ALOX15 arachidonate 15-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANXA5 annexin A5
APCS amyloid P component, serum
APOE apolipoprotein E
APOL1 apolipoprotein L, 1
ART1 ADP-ribosyltransferase 1
ATM ATM serine/threonine kinase
ATN1 atrophin 1
ATR ATR serine/threonine kinase
AXL AXL receptor tyrosine kinase
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL2 B-cell CLL/lymphoma 2
BECN1 beclin 1, autophagy related
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD2 bromodomain containing 2
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C3 complement component 3
C3AR1 complement component 3a receptor 1
C4A complement component 4A (Rodgers blood group)
C5AR1 complement component 5a receptor 1
C6 complement component 6
C9 complement component 9
CABIN1 calcineurin binding protein 1
CADM1 cell adhesion molecule 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CAST calpastatin
CCL1 chemokine (C-C motif) ligand 1
CCL13 chemokine (C-C motif) ligand 13
CCL2 chemokine (C-C motif) ligand 2
CCL22 chemokine (C-C motif) ligand 22
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCN2 cellular communication network factor 2
CCR4 chemokine (C-C motif) receptor 4
CCR6 chemokine (C-C motif) receptor 6
CD163 CD163 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD46 CD46 molecule, complement regulatory protein
CD48 CD48 molecule
CD59 CD59 molecule, complement regulatory protein
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79A CD79a molecule, immunoglobulin-associated alpha
CD81 CD81 molecule
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CERT1 ceramide transporter 1
CFD complement factor D (adipsin)
CFH complement factor H
CFHR5 complement factor H-related 5
CFI complement factor I
CHP1 calcineurin-like EF-hand protein 1
CIC capicua transcriptional repressor
CLCN5 chloride channel, voltage-sensitive 5
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)
CNN1 calponin 1, basic, smooth muscle
COL18A1 collagen, type XVIII, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A5 collagen, type IV, alpha 5
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CP ceruloplasmin (ferroxidase)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRP C-reactive protein, pentraxin-related
CSF3 colony stimulating factor 3 (granulocyte)
CST3 cystatin C
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUX1 cut-like homeobox 1
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DDR1 discoidin domain receptor tyrosine kinase 1
DES desmin
DGKE diacylglycerol kinase, epsilon 64kDa
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNASE1 deoxyribonuclease I
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EGF epidermal growth factor
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF1 eukaryotic translation initiation factor 1
ELANE elastase, neutrophil expressed
ELP1 elongator acetyltransferase complex subunit 1
EMB embigin
EPHX2 epoxide hydrolase 2, cytoplasmic
ERBB2 erb-b2 receptor tyrosine kinase 2
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
ETV6 ets variant 6
EXOSC3 exosome component 3
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBN1 fibrillin 1
FCAR Fc fragment of IgA receptor
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGF23 fibroblast growth factor 23
FH fumarate hydratase
FHL1 four and a half LIM domains 1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLII flightless I homolog (Drosophila)
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXD1 forkhead box D1
FOXP2 forkhead box P2
FOXP3 forkhead box P3
GALNS galactosamine (N-acetyl)-6-sulfatase
GAS6 growth arrest-specific 6
GAST gastrin
GDNF glial cell derived neurotrophic factor
GJA5 gap junction protein, alpha 5, 40kDa
GLP1R glucagon-like peptide 1 receptor
GREM1 gremlin 1, DAN family BMP antagonist
HAVCR1 hepatitis A virus cellular receptor 1
HBEGF heparin-binding EGF-like growth factor
HCLS1 hematopoietic cell-specific Lyn substrate 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HHAT hedgehog acyltransferase
HLA-A major histocompatibility complex, class I, A
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ICAM1 intercellular adhesion molecule 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA2 interferon, alpha 2
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGK immunoglobulin kappa locus
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL13 interleukin 13
IL17A interleukin 17A
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL22 interleukin 22
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL4 interleukin 4
IL6 interleukin 6
IRAK4 interleukin-1 receptor-associated kinase 4
IRF5 interferon regulatory factor 5
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA8 integrin, alpha 8
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KHSRP KH-type splicing regulatory protein
KIF1B kinesin family member 1B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
LAGE3 L antigen family, member 3
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
LAYN layilin
LMX1B LIM homeobox transcription factor 1, beta
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOX lysyl oxidase
LTBP1 latent transforming growth factor beta binding protein 1
LTC4S leukotriene C4 synthase
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MAX MYC associated factor X
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MEFV Mediterranean fever
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIP major intrinsic protein of lens fiber
MMP1 matrix metallopeptidase 1
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MPO myeloperoxidase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSN moesin
MTSS1L metastasis suppressor 1-like
MUC1 mucin 1, cell surface associated
MYD88 myeloid differentiation primary response 88
MYH9 myosin, heavy chain 9, non-muscle
MYL9 myosin, light chain 9, regulatory
NEO1 neogenin 1
NEUROG1 neurogenin 1
NGF nerve growth factor (beta polypeptide)
NLRP3 NLR family, pyrin domain containing 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NOV nephroblastoma overexpressed
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NR2E3 nuclear receptor subfamily 2, group E, member 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTS neurotensin
OSGEP O-sialoglycoprotein endopeptidase
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PADI4 peptidyl arginine deiminase, type IV
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAMR1 peptidase domain containing associated with muscle regeneration 1
PCNA proliferating cell nuclear antigen
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFB platelet-derived growth factor beta polypeptide
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PER2 period circadian clock 2
PKN1 protein kinase N1
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLB1 phospholipase B1
PLEC plectin
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLG plasminogen
POC5 POC5 centriolar protein
POMC proopiomelanocortin
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PRF1 perforin 1 (pore forming protein)
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRTN3 proteinase 3
PSIP1 PC4 and SFRS1 interacting protein 1
PTAFR platelet-activating factor receptor
RARA retinoic acid receptor, alpha
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM45 RNA binding motif protein 45
REN renin
RET ret proto-oncogene
RGS2 regulator of G-protein signaling 2
RHOV ras homolog family member V
RNLS renalase, FAD-dependent amine oxidase
RNPC3 RNA-binding region (RNP1, RRM) containing 3
RPP14 ribonuclease P/MRP 14kDa subunit
RPS27A ribosomal protein S27a
RUNX1 runt-related transcription factor 1
S100A10 S100 calcium binding protein A10
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHAF2 succinate dehydrogenase complex assembly factor 2
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SF3B6 splicing factor 3b, subunit 6, 14kDa
SH2D1A SH2 domain containing 1A
SIGLEC7 sialic acid binding Ig-like lectin 7
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNRPA small nuclear ribonucleoprotein polypeptide A
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
SRR serine racemase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
SUB1 SUB1 homolog (S. cerevisiae)
SYK spleen tyrosine kinase
TAAR5 trace amine associated receptor 5
TAGLN transgelin
TBXAS1 thromboxane A synthase 1 (platelet)
TCF3 transcription factor 3
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
THBD thrombomodulin
THEMIS2 thymocyte selection associated family member 2
THY1 Thy-1 cell surface antigen
TIMP1 TIMP metallopeptidase inhibitor 1
TLR1 toll-like receptor 1
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TMEM127 transmembrane protein 127
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNIP1 TNFAIP3 interacting protein 1
TP53RK TP53 regulating kinase
TPRKB TP53RK binding protein
TRIM21 tripartite motif containing 21
UBC ubiquitin C
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UMOD uromodulin
USP2 ubiquitin specific peptidase 2
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
WDR19 WD repeat domain 19
WT1 Wilms tumor 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZMYM2 zinc finger, MYM-type 2