Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the Gly-His-Lys-6570 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
ACTB | actin, beta |
AP1AR | adaptor-related protein complex 1 associated regulatory protein |
AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
BMPR1A | bone morphogenetic protein receptor, type IA |
C16ORF59 | chromosome 16 open reading frame 59 |
C6ORF62 | chromosome 6 open reading frame 62 |
CALU | calumenin |
CDK2 | cyclin-dependent kinase 2 |
CLIP1 | CAP-GLY domain containing linker protein 1 |
COMMD10 | COMM domain containing 10 |
CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
DBT | dihydrolipoamide branched chain transacylase E2 |
EIF5A | eukaryotic translation initiation factor 5A |
ENO1 | enolase 1, (alpha) |
F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
F8 | coagulation factor VIII, procoagulant component |
FH | fumarate hydratase |
FUS | FUS RNA binding protein |
FZD8 | frizzled class receptor 8 |
GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
GALK2 | galactokinase 2 |
GANAB | glucosidase, alpha; neutral AB |
GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
GDE1 | glycerophosphodiester phosphodiesterase 1 |
GDI2 | GDP dissociation inhibitor 2 |
GLS | glutaminase |
GLUD2 | glutamate dehydrogenase 2 |
GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
GPHN | gephyrin |
GRPR | gastrin-releasing peptide receptor |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
H2AFX | H2A histone family, member X |
HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
KLHDC3 | kelch domain containing 3 |
LRRC61 | leucine rich repeat containing 61 |
LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
MAGEF1 | melanoma antigen family F1 |
MAP4 | microtubule-associated protein 4 |
MAT2A | methionine adenosyltransferase II, alpha |
MBTPS1 | membrane-bound transcription factor peptidase, site 1 |
MED6 | mediator complex subunit 6 |
MPZL1 | myelin protein zero-like 1 |
MSH6 | mutS homolog 6 |
NMD3 | NMD3 ribosome export adaptor |
NOTCH2 | notch 2 |
NOV | nephroblastoma overexpressed |
OCRL | oculocerebrorenal syndrome of Lowe |
OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
PAPOLA | poly(A) polymerase alpha |
PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
PLAU | plasminogen activator, urokinase |
PLEC | plectin |
POLR2E | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa |
POMT2 | protein-O-mannosyltransferase 2 |
PPIF | peptidylprolyl isomerase F |
PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
PRNP | prion protein |
PRPF4 | pre-mRNA processing factor 4 |
PRR3 | proline rich 3 |
PSAT1 | phosphoserine aminotransferase 1 |
PSEN1 | presenilin 1 |
RAB3B | RAB3B, member RAS oncogene family |
RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
RBBP4 | retinoblastoma binding protein 4 |
RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
RFC5 | replication factor C (activator 1) 5, 36.5kDa |
RNF24 | ring finger protein 24 |
RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
RUNX1-IT1 | RUNX1 intronic transcript 1 |
SEC23A | Sec23 homolog A (S. cerevisiae) |
SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
SH2D4A | SH2 domain containing 4A |
SKA1 | spindle and kinetochore associated complex subunit 1 |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
SPAG9 | sperm associated antigen 9 |
STIP1 | stress-induced phosphoprotein 1 |
SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
SYPL1 | synaptophysin-like 1 |
TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
TAGLN2 | transgelin 2 |
TLK2 | tousled-like kinase 2 |
TMEM230 | transmembrane protein 230 |
TSC2 | tuberous sclerosis 2 |
TSKU | tsukushi, small leucine rich proteoglycan |
TSPAN4 | tetraspanin 4 |
UBE2N | ubiquitin-conjugating enzyme E2N |
UBE4B | ubiquitination factor E4B |
UHRF1BP1L | UHRF1 binding protein 1-like |
USP34 | ubiquitin specific peptidase 34 |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
ZNF148 | zinc finger protein 148 |
ZNF227 | zinc finger protein 227 |
Symbol | Name |
---|---|
ACAD10 | acyl-CoA dehydrogenase family, member 10 |
BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
BBC3 | BCL2 binding component 3 |
C11ORF63 | chromosome 11 open reading frame 63 |
C19ORF40 | chromosome 19 open reading frame 40 |
C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
C9ORF114 | chromosome 9 open reading frame 114 |
CDADC1 | cytidine and dCMP deaminase domain containing 1 |
CHKB | choline kinase beta |
CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
CLSPN | claspin |
CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
COBL | cordon-bleu WH2 repeat protein |
CST4 | cystatin S |
CXCR2 | chemokine (C-X-C motif) receptor 2 |
CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
DMBT1 | deleted in malignant brain tumors 1 |
DSPP | dentin sialophosphoprotein |
FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
FCHO1 | FCH domain only 1 |
GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
GRTP1 | growth hormone regulated TBC protein 1 |
HIST1H1D | histone cluster 1, H1d |
HIST1H1E | histone cluster 1, H1e |
HIST1H4C | histone cluster 1, H4c |
HOXC4 | homeobox C4 |
HYI | hydroxypyruvate isomerase (putative) |
IGFLR1 | IGF-like family receptor 1 |
IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
IL37 | interleukin 37 |
ITPKC | inositol-trisphosphate 3-kinase C |
KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
KLHL25 | kelch-like family member 25 |
KPTN | kaptin (actin binding protein) |
LRRK1 | leucine-rich repeat kinase 1 |
MBTD1 | mbt domain containing 1 |
ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
MILR1 | mast cell immunoglobulin-like receptor 1 |
MMRN2 | multimerin 2 |
MNX1 | motor neuron and pancreas homeobox 1 |
MYO15A | myosin XVA |
NDE1 | nudE neurodevelopment protein 1 |
NDP | Norrie disease (pseudoglioma) |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NIPAL2 | NIPA-like domain containing 2 |
NOTCH4 | notch 4 |
NPIPB15 | nuclear pore complex interacting protein family, member B15 |
OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
PARM1 | prostate androgen-regulated mucin-like protein 1 |
PBLD | phenazine biosynthesis-like protein domain containing |
PCDH12 | protocadherin 12 |
PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
PDE12 | phosphodiesterase 12 |
PMCH | pro-melanin-concentrating hormone |
PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
PODNL1 | podocan-like 1 |
POLL | polymerase (DNA directed), lambda |
PSG4 | pregnancy specific beta-1-glycoprotein 4 |
RAB36 | RAB36, member RAS oncogene family |
RAB3A | RAB3A, member RAS oncogene family |
RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
RNF126P1 | ring finger protein 126 pseudogene 1 |
RPL23AP32 | ribosomal protein L23a pseudogene 32 |
RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
SARS2 | seryl-tRNA synthetase 2, mitochondrial |
SCD5 | stearoyl-CoA desaturase 5 |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
SH2D2A | SH2 domain containing 2A |
SIRT2 | sirtuin 2 |
SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
SLITRK5 | SLIT and NTRK-like family, member 5 |
SMR3A | submaxillary gland androgen regulated protein 3A |
SPRR2B | small proline-rich protein 2B |
SPTBN2 | spectrin, beta, non-erythrocytic 2 |
STARD5 | StAR-related lipid transfer (START) domain containing 5 |
STX17 | syntaxin 17 |
SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
THAP7 | THAP domain containing 7 |
TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
TRAF2 | TNF receptor-associated factor 2 |
UBQLN4 | ubiquilin 4 |
UNC13A | unc-13 homolog A (C. elegans) |
XYLT2 | xylosyltransferase II |
ZBTB22 | zinc finger and BTB domain containing 22 |
ZDHHC11 | zinc finger, DHHC-type containing 11 |
ZNF205 | zinc finger protein 205 |
ZNF528 | zinc finger protein 528 |
ZNF639 | zinc finger protein 639 |
ZNF668 | zinc finger protein 668 |