| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/14982 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Glycyrrhizic acid relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PAQR4 | progestin and adipoQ receptor family member IV | 0.51 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | 0.5 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.45 |
| OSMR | oncostatin M receptor | 0.43 |
| CLUH | clustered mitochondria (cluA/CLU1) homolog | 0.41 |
| PRR5 | proline rich 5 (renal) | 0.39 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.39 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.38 |
| C5ORF34 | chromosome 5 open reading frame 34 | 0.38 |
| DLEC1 | deleted in lung and esophageal cancer 1 | 0.36 |
| TASP1 | taspase, threonine aspartase, 1 | 0.35 |
| YBX3 | Y box binding protein 3 | 0.35 |
| METTL25 | methyltransferase like 25 | 0.34 |
| ZFAND2B | zinc finger, AN1-type domain 2B | 0.33 |
| TMEM39A | transmembrane protein 39A | 0.32 |
| TTC39C | tetratricopeptide repeat domain 39C | 0.32 |
| PPP1R35 | protein phosphatase 1, regulatory subunit 35 | 0.32 |
| H3C1 | H3 clustered histone 1 | 0.3 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.29 |
| EPS8L1 | EPS8-like 1 | 0.28 |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 | 0.27 |
| HINT3 | histidine triad nucleotide binding protein 3 | 0.26 |
| DEAF1 | DEAF1 transcription factor | 0.26 |
| HIST2H2AA3 | histone cluster 2, H2aa3 | 0.26 |
| MFSD6 | major facilitator superfamily domain containing 6 | 0.26 |
| ADGRL1 | adhesion G protein-coupled receptor L1 | 0.26 |
| LRRC45 | leucine rich repeat containing 45 | 0.26 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.26 |
| FHL2 | four and a half LIM domains 2 | 0.26 |
| RIC1 | RAB6A GEF complex partner 1 | 0.25 |
| RASSF7 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 | 0.25 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.25 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.25 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.25 |
| ANAPC11 | anaphase promoting complex subunit 11 | 0.25 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.25 |
| SF3A3 | splicing factor 3a, subunit 3, 60kDa | 0.24 |
| VWDE | von Willebrand factor D and EGF domains | 0.24 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.24 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.24 |
| RPL35 | ribosomal protein L35 | 0.23 |
| JUND | jun D proto-oncogene | 0.23 |
| MIF4GD | MIF4G domain containing | 0.23 |
| RPS8 | ribosomal protein S8 | 0.23 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 | 0.23 |
| AKTIP | AKT interacting protein | 0.23 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | 0.23 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.22 |
| PRRX2 | paired related homeobox 2 | 0.22 |
| CAPN15 | calpain 15 | 0.22 |
| CRIPT | cysteine-rich PDZ-binding protein | 0.22 |
| JMJD4 | jumonji domain containing 4 | 0.22 |
| EI24 | etoposide induced 2.4 | 0.22 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.22 |
| CCDC28A | coiled-coil domain containing 28A | 0.22 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | 0.22 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.22 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.22 |
| RPL37 | ribosomal protein L37 | 0.22 |
| DYNLL2 | dynein, light chain, LC8-type 2 | 0.21 |
| TXNL4B | thioredoxin-like 4B | 0.21 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.21 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.21 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.21 |
| APOLTP | apolipoprotein lipid transfer particle homolog | 0.21 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.21 |
| CFL1 | cofilin 1 (non-muscle) | 0.21 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.21 |
| SNX19 | sorting nexin 19 | 0.21 |
| AMPD1 | adenosine monophosphate deaminase 1 | 0.21 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.21 |
| RPL19 | ribosomal protein L19 | 0.2 |
| TBC1D30 | TBC1 domain family, member 30 | 0.2 |
| RPS6 | ribosomal protein S6 | 0.2 |
| RPL36A | ribosomal protein L36a | 0.2 |
| ZNF692 | zinc finger protein 692 | 0.2 |
| HOXB7 | homeobox B7 | 0.2 |
| CRELD1 | cysteine-rich with EGF-like domains 1 | 0.2 |
| TMC6 | transmembrane channel-like 6 | 0.2 |
| C12ORF45 | chromosome 12 open reading frame 45 | 0.2 |
| RPL24 | ribosomal protein L24 | 0.2 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | 0.19 |
| FEM1A | fem-1 homolog a (C. elegans) | 0.19 |
| SPATA33 | spermatogenesis associated 33 | 0.19 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.19 |
| MT1E | metallothionein 1E | 0.19 |
| RPS27A | ribosomal protein S27a | 0.19 |
| RABIF | RAB interacting factor | 0.19 |
| RPL27A | ribosomal protein L27a | 0.19 |
| RPS18 | ribosomal protein S18 | 0.19 |
| RPS17 | ribosomal protein S17 | 0.19 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.19 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.18 |
| FUS | FUS RNA binding protein | 0.18 |
| AIF1L | allograft inflammatory factor 1-like | 0.18 |
| HIST2H2BC | histone cluster 2, H2bc (pseudogene) | 0.18 |
| ENSA | endosulfine alpha | 0.18 |
| ESRRA | estrogen-related receptor alpha | 0.18 |
| H3-3A | H3.3 histone A | 0.18 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARL13B | ADP-ribosylation factor-like 13B | -1.65 |
| MYPOP | Myb-related transcription factor, partner of profilin | -1.11 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | -1.1 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.9 |
| LMOD1 | leiomodin 1 (smooth muscle) | -0.86 |
| SBSN | suprabasin | -0.79 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 | -0.74 |
| FAM171A2 | family with sequence similarity 171, member A2 | -0.73 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.67 |
| CHKB | choline kinase beta | -0.65 |
| FGB | fibrinogen beta chain | -0.61 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.6 |
| ZNF616 | zinc finger protein 616 | -0.6 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.59 |
| SLC45A1 | solute carrier family 45, member 1 | -0.57 |
| TAF1L | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like | -0.56 |
| SERINC1 | serine incorporator 1 | -0.56 |
| AREL1 | apoptosis resistant E3 ubiquitin protein ligase 1 | -0.53 |
| TYSND1 | trypsin domain containing 1 | -0.51 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | -0.51 |
| PLEKHA3 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 | -0.51 |
| MYT1 | myelin transcription factor 1 | -0.51 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.5 |
| SLC25A30 | solute carrier family 25, member 30 | -0.5 |
| LRP6 | low density lipoprotein receptor-related protein 6 | -0.49 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.49 |
| MED12L | mediator complex subunit 12-like | -0.49 |
| ZNF581 | zinc finger protein 581 | -0.48 |
| CINP | cyclin-dependent kinase 2 interacting protein | -0.48 |
| PKHD1L1 | polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 | -0.48 |
| MPZL2 | myelin protein zero-like 2 | -0.48 |
| RTL8C | retrotransposon Gag like 8C | -0.47 |
| TEX15 | testis expressed 15 | -0.47 |
| GLRX | glutaredoxin (thioltransferase) | -0.47 |
| PCDH1 | protocadherin 1 | -0.46 |
| ICAM1 | intercellular adhesion molecule 1 | -0.46 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.45 |
| TMC4 | transmembrane channel-like 4 | -0.45 |
| NUCB2 | nucleobindin 2 | -0.44 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | -0.44 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.43 |
| SKIL | SKI-like proto-oncogene | -0.43 |
| SAMD8 | sterile alpha motif domain containing 8 | -0.43 |
| MCOLN1 | mucolipin 1 | -0.42 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.42 |
| TNS2 | tensin 2 | -0.41 |
| SYNE4 | spectrin repeat containing, nuclear envelope family member 4 | -0.41 |
| SRR | serine racemase | -0.41 |
| HSCB | HscB mitochondrial iron-sulfur cluster co-chaperone | -0.41 |
| IFT140 | intraflagellar transport 140 | -0.41 |
| RPGRIP1L | RPGRIP1-like | -0.4 |
| FN1 | fibronectin 1 | -0.4 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | -0.4 |
| GSDME | gasdermin E | -0.4 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | -0.4 |
| SFR1 | SWI5-dependent recombination repair 1 | -0.39 |
| LIPH | lipase, member H | -0.39 |
| COA6 | cytochrome c oxidase assembly factor 6 | -0.39 |
| GID4 | GID complex subunit 4 | -0.38 |
| NCKAP1L | NCK-associated protein 1-like | -0.38 |
| MSRB2 | methionine sulfoxide reductase B2 | -0.38 |
| SP4 | Sp4 transcription factor | -0.38 |
| PET117 | PET117 homolog (S. cerevisiae) | -0.38 |
| LYSMD1 | LysM, putative peptidoglycan-binding, domain containing 1 | -0.38 |
| USP20 | ubiquitin specific peptidase 20 | -0.37 |
| HYKK | hydroxylysine kinase | -0.37 |
| HPCAL4 | hippocalcin like 4 | -0.37 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.36 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.36 |
| ANKRD16 | ankyrin repeat domain 16 | -0.36 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.36 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) | -0.36 |
| MT-CO1 | cytochrome c oxidase subunit I | -0.36 |
| TIPIN | TIMELESS interacting protein | -0.36 |
| TXNDC11 | thioredoxin domain containing 11 | -0.35 |
| PIP | prolactin-induced protein | -0.35 |
| ZNRD2 | zinc ribbon domain containing 2 | -0.35 |
| RAB27A | RAB27A, member RAS oncogene family | -0.35 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D | -0.35 |
| ECM1 | extracellular matrix protein 1 | -0.35 |
| ROGDI | rogdi homolog (Drosophila) | -0.35 |
| GPATCH11 | G patch domain containing 11 | -0.34 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.33 |
| ACSF2 | acyl-CoA synthetase family member 2 | -0.33 |
| SNX33 | sorting nexin 33 | -0.33 |
| ZNF691 | zinc finger protein 691 | -0.33 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 | -0.33 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) | -0.33 |
| ZNF337 | zinc finger protein 337 | -0.32 |
| NEMP1 | nuclear envelope integral membrane protein 1 | -0.32 |
| SASH1 | SAM and SH3 domain containing 1 | -0.32 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.32 |
| THUMPD2 | THUMP domain containing 2 | -0.32 |
| NKAPD1 | NKAP domain containing 1 | -0.31 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.31 |
| BEND7 | BEN domain containing 7 | -0.31 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.31 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.31 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 | -0.3 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.3 |
