| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glycyrrhizic acid_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.106164 |
| FLNA | filamin A, alpha | 0.0921428 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0865049 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0861102 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0848143 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0802249 |
| GPC6 | glypican 6 | 0.0768566 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0737212 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0704266 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0696844 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0672605 |
| NAV2 | neuron navigator 2 | 0.0653438 |
| FRMD4A | FERM domain containing 4A | 0.0651792 |
| ATP13A3 | ATPase type 13A3 | 0.0630092 |
| PKM | pyruvate kinase, muscle | 0.0608276 |
| POTEF | POTE ankyrin domain family, member F | 0.0607423 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0606252 |
| FAT1 | FAT atypical cadherin 1 | 0.05847 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0576455 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0566971 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.055133 |
| ACTG1 | actin gamma 1 | 0.0515667 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0495398 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0467172 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0459088 |
| LDHA | lactate dehydrogenase A | 0.0453319 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0443049 |
| PFN1 | profilin 1 | 0.0437266 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0422938 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0422507 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0421148 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0416669 |
| CADM1 | cell adhesion molecule 1 | 0.0403027 |
| FLNC | filamin C, gamma | 0.0401821 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.040139 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0396984 |
| SPAG9 | sperm associated antigen 9 | 0.039618 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0386966 |
| MYADM | myeloid-associated differentiation marker | 0.0377144 |
| STOM | stomatin | 0.0372663 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0362083 |
| CD68 | CD68 molecule | 0.0352459 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0350835 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0345632 |
| PGK1 | phosphoglycerate kinase 1 | 0.0343931 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0337491 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0335062 |
| HMGA1 | high mobility group AT-hook 1 | 0.0324315 |
| TUBB | tubulin, beta class I | 0.0321846 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.032112 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0317962 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0315004 |
| FN1 | fibronectin 1 | 0.0307983 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0305019 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0304322 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0302179 |
| ANXA5 | annexin A5 | 0.0295307 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0295143 |
| NCOR2 | nuclear receptor corepressor 2 | 0.029163 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0285641 |
| RPN1 | ribophorin I | 0.0284237 |
| CCNL1 | cyclin L1 | 0.0283165 |
| RUNX2 | runt-related transcription factor 2 | 0.0282968 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0280957 |
| ATXN2L | ataxin 2-like | 0.0273242 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0272459 |
| AGRN | agrin | 0.027054 |
| FOXO3 | forkhead box O3 | 0.0268255 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0264788 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0263841 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0259938 |
| WDR43 | WD repeat domain 43 | 0.0258764 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0256909 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.025606 |
| PML | promyelocytic leukemia | 0.0254333 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0254217 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0253458 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0253275 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.0251151 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0250605 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0250493 |
| BNC2 | basonuclin 2 | 0.0246812 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0246631 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0244792 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0243771 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.024037 |
| PLEC | plectin | 0.0238621 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0237736 |
| ANKRD10 | ankyrin repeat domain 10 | 0.023324 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 0.022917 |
| GANAB | glucosidase, alpha; neutral AB | 0.0228893 |
| SCFD2 | sec1 family domain containing 2 | 0.0226681 |
| RNF220 | ring finger protein 220 | 0.0225912 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0225092 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.0224568 |
| FOXK1 | forkhead box K1 | 0.0223151 |
| RBM33 | RNA binding motif protein 33 | 0.0221286 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0219263 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0218839 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0214985 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.250868 |
| FTL | ferritin, light polypeptide | -0.214818 |
| TXNRD1 | thioredoxin reductase 1 | -0.144686 |
| TMSB10 | thymosin beta 10 | -0.122724 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0853119 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0774353 |
| VIM | vimentin | -0.0768877 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0764944 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0748791 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.071195 |
| APOL1 | apolipoprotein L, 1 | -0.0685911 |
| PTMA | prothymosin, alpha | -0.060603 |
| KYNU | kynureninase | -0.0598892 |
| RAI14 | retinoic acid induced 14 | -0.0591881 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0582589 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0568668 |
| CENPF | centromere protein F, 350/400kDa | -0.0564766 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.05203 |
| RRBP1 | ribosome binding protein 1 | -0.0499916 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0492028 |
| B2M | beta-2-microglobulin | -0.0484874 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.04818 |
| CANX | calnexin | -0.0477478 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0472759 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0467424 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0466988 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0466807 |
| RPS2 | ribosomal protein S2 | -0.0464067 |
| TPM3 | tropomyosin 3 | -0.0459884 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0458951 |
| RPL26 | ribosomal protein L26 | -0.0458037 |
| RPS6 | ribosomal protein S6 | -0.0453794 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0446512 |
| RPL31 | ribosomal protein L31 | -0.0443736 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0434818 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.040691 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0398287 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0397464 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0375924 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0370019 |
| RPS8 | ribosomal protein S8 | -0.0366025 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0365865 |
| S100A10 | S100 calcium binding protein A10 | -0.036401 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.033984 |
| RPS27A | ribosomal protein S27a | -0.0337263 |
| GOLGB1 | golgin B1 | -0.0334261 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0332665 |
| RPS24 | ribosomal protein S24 | -0.0332302 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0329092 |
| RPL19 | ribosomal protein L19 | -0.0326979 |
| RPS5 | ribosomal protein S5 | -0.0326619 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0326149 |
| RPS12 | ribosomal protein S12 | -0.032574 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0318044 |
| MX1 | MX dynamin-like GTPase 1 | -0.0311083 |
| RPS17 | ribosomal protein S17 | -0.0310435 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0306696 |
| SLFN5 | schlafen family member 5 | -0.0306305 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0304182 |
| RIGI | RNA sensor RIG-I | -0.0302483 |
| VCAN | versican | -0.030119 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0299744 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0299179 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0298427 |
| RPL12 | ribosomal protein L12 | -0.0296134 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0293823 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0290477 |
| SET | SET nuclear proto-oncogene | -0.0289813 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0287929 |
| TKT | transketolase | -0.0285332 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0281929 |
| VCL | vinculin | -0.0281567 |
| TPM4 | tropomyosin 4 | -0.0280604 |
| RAB10 | RAB10, member RAS oncogene family | -0.028048 |
| SQSTM1 | sequestosome 1 | -0.027916 |
| ANXA1 | annexin A1 | -0.0274153 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0271989 |
| GOLGA3 | golgin A3 | -0.0271144 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0268144 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.026711 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0265243 |
| CBX3 | chromobox homolog 3 | -0.0264325 |
| VCP | valosin containing protein | -0.0262653 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0261865 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0261653 |
| TUSC3 | tumor suppressor candidate 3 | -0.0261381 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0260241 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0259509 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.025876 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0255591 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0253527 |
| SETX | senataxin | -0.0252389 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0251741 |
| TPR | translocated promoter region, nuclear basket protein | -0.0251528 |
| RPS3 | ribosomal protein S3 | -0.0249275 |
| TUT7 | terminal uridylyl transferase 7 | -0.0247059 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0246337 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0243809 |
| MKI67 | marker of proliferation Ki-67 | -0.024288 |
| GLIS3 | GLIS family zinc finger 3 | -0.0241198 |
