| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Glycyrrhizic acid_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.160076 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.155557 |
| LMTK2 | lemur tyrosine kinase 2 | 0.108206 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0883554 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0845991 |
| ACTG1 | actin gamma 1 | 0.0809013 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0689967 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0625126 |
| PLEC | plectin | 0.0599074 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0594379 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0506047 |
| SMAD3 | SMAD family member 3 | 0.0470015 |
| HMGA1 | high mobility group AT-hook 1 | 0.0466975 |
| CCNL1 | cyclin L1 | 0.0465649 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0450792 |
| TXNRD1 | thioredoxin reductase 1 | 0.0446429 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0441507 |
| PTK2 | protein tyrosine kinase 2 | 0.0432949 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0417061 |
| KLK10 | kallikrein-related peptidase 10 | 0.0413711 |
| TRRAP | transformation/transcription domain-associated protein | 0.0413453 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0393935 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0392706 |
| FLNB | filamin B, beta | 0.0386816 |
| RASAL2 | RAS protein activator like 2 | 0.0378685 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0344053 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.034193 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0333675 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0330082 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0327475 |
| FLNA | filamin A, alpha | 0.0321832 |
| PMM2 | phosphomannomutase 2 | 0.0319362 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0304808 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0294632 |
| HSPA8 | heat shock 70kDa protein 8 | 0.029241 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0291264 |
| KRT8 | keratin 8, type II | 0.029114 |
| RPL13A | ribosomal protein L13a | 0.0289797 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0282702 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0280695 |
| EFNA5 | ephrin-A5 | 0.0273131 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0272826 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0266421 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0266333 |
| NCKAP1 | NCK-associated protein 1 | 0.0263913 |
| FOXO3 | forkhead box O3 | 0.0253792 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0249577 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.024783 |
| MCL1 | myeloid cell leukemia 1 | 0.024696 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0246661 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0244411 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0243936 |
| SIK3 | SIK family kinase 3 | 0.0243204 |
| EFNB2 | ephrin-B2 | 0.0241987 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0241939 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.023367 |
| ACTN4 | actinin, alpha 4 | 0.0232088 |
| FOSL1 | FOS-like antigen 1 | 0.0231871 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0228116 |
| NUP98 | nucleoporin 98kDa | 0.0227177 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.02259 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0224973 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0224337 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0222383 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0221167 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0220517 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0220412 |
| RPS2 | ribosomal protein S2 | 0.0219697 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0217288 |
| UPP1 | uridine phosphorylase 1 | 0.021665 |
| RPL23 | ribosomal protein L23 | 0.0215688 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0214805 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0214155 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0210808 |
| VMP1 | vacuole membrane protein 1 | 0.0210499 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0208509 |
| WDR43 | WD repeat domain 43 | 0.0208261 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0206265 |
| CLMP | CXADR-like membrane protein | 0.020472 |
| RPS26 | ribosomal protein S26 | 0.0203701 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.020301 |
| SBDS | Shwachman-Bodian-Diamond syndrome | 0.0200312 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0198776 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0197231 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0196947 |
| SULF2 | sulfatase 2 | 0.0196819 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.019612 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0195262 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0195105 |
| RPL9 | ribosomal protein L9 | 0.0192265 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0191414 |
| RPS21 | ribosomal protein S21 | 0.0190446 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0190061 |
| ARHGAP17 | Rho GTPase activating protein 17 | 0.0190043 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0189877 |
| XYLT1 | xylosyltransferase I | 0.0189459 |
| KIF5B | kinesin family member 5B | 0.0188835 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0188425 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0188039 |
| CRY1 | cryptochrome circadian clock 1 | 0.0187025 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.233387 |
| TMSB10 | thymosin beta 10 | -0.212944 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.189893 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.142193 |
| S100A10 | S100 calcium binding protein A10 | -0.132229 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123991 |
| VIM | vimentin | -0.116726 |
| PTMA | prothymosin, alpha | -0.113291 |
| ITGA6 | integrin, alpha 6 | -0.110383 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0975542 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0901461 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0893532 |
| VCAN | versican | -0.0848853 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0841614 |
| EZR | ezrin | -0.0818046 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0809802 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0807052 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0783001 |
| DSG2 | desmoglein 2 | -0.0698643 |
| AHNAK | AHNAK nucleoprotein | -0.0656968 |
| FAM107B | family with sequence similarity 107, member B | -0.0643638 |
| FTL | ferritin, light polypeptide | -0.0586563 |
| OGA | O-GlcNAcase | -0.0549028 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0547984 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0544917 |
| POTEF | POTE ankyrin domain family, member F | -0.0537488 |
| UBC | ubiquitin C | -0.0524205 |
| LDHA | lactate dehydrogenase A | -0.0522512 |
| LAMA4 | laminin, alpha 4 | -0.0517894 |
| PERP | PERP, TP53 apoptosis effector | -0.051203 |
| LMO7 | LIM domain 7 | -0.0510487 |
| FAM3C | family with sequence similarity 3, member C | -0.0487001 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0478396 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0472311 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0468215 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0459839 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0455661 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0453561 |
| KLF6 | Kruppel-like factor 6 | -0.0450463 |
| RIOK3 | RIO kinase 3 | -0.044624 |
| S100A11 | S100 calcium binding protein A11 | -0.0444463 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0436213 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0433461 |
| FAM13A | family with sequence similarity 13, member A | -0.0431673 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.04315 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0422867 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0421396 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0412456 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.04085 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0404364 |
| JMJD1C | jumonji domain containing 1C | -0.0371588 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.036995 |
| OPTN | optineurin | -0.0361116 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.035901 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0355507 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0352773 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0350641 |
| MYO1E | myosin IE | -0.0344013 |
| ANXA2 | annexin A2 | -0.0343733 |
| DSPP | dentin sialophosphoprotein | -0.0341218 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0337196 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0330687 |
| TXNIP | thioredoxin interacting protein | -0.0330505 |
| CD9 | CD9 molecule | -0.0325367 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.031864 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0316914 |
| RPS3 | ribosomal protein S3 | -0.0316906 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0314819 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0312799 |
| XPO1 | exportin 1 | -0.0309994 |
| INSIG2 | insulin induced gene 2 | -0.0309859 |
| SDC4 | syndecan 4 | -0.0308986 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0306129 |
| ANXA1 | annexin A1 | -0.030557 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0305336 |
| RPL31 | ribosomal protein L31 | -0.0299915 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0299896 |
| DSTN | destrin (actin depolymerizing factor) | -0.0293757 |
| SEPTIN7 | septin 7 | -0.0288634 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0286893 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0285889 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0280174 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.027922 |
| ENO1 | enolase 1, (alpha) | -0.0278102 |
| LYZ | lysozyme | -0.026953 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0268641 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0265109 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0264837 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0263974 |
| DUSP6 | dual specificity phosphatase 6 | -0.0259149 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0257905 |
| USP3 | ubiquitin specific peptidase 3 | -0.0257824 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0256317 |
| KIAA0040 | KIAA0040 | -0.0254537 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0253172 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0247994 |
| CSTB | cystatin B (stefin B) | -0.0245895 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0242313 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.024089 |
| ARF4 | ADP-ribosylation factor 4 | -0.0238021 |