| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glycyrrhizic acid_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0899364 |
| NDRG1 | N-myc downstream regulated 1 | 0.0732843 |
| ACTG1 | actin gamma 1 | 0.0629701 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0614127 |
| CLTC | clathrin, heavy chain (Hc) | 0.053432 |
| LASP1 | LIM and SH3 protein 1 | 0.0508564 |
| FASN | fatty acid synthase | 0.0480864 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0469287 |
| DTNA | dystrobrevin, alpha | 0.0465677 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0443494 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0434008 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0430862 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0429234 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0427227 |
| GRB7 | growth factor receptor-bound protein 7 | 0.0422617 |
| PKM | pyruvate kinase, muscle | 0.0418968 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0412147 |
| CCNL1 | cyclin L1 | 0.0401274 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0397643 |
| LDHA | lactate dehydrogenase A | 0.0391601 |
| MCL1 | myeloid cell leukemia 1 | 0.0391271 |
| POTEF | POTE ankyrin domain family, member F | 0.0380303 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0378553 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0367044 |
| VEGFA | vascular endothelial growth factor A | 0.0353307 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0345606 |
| CEP250 | centrosomal protein 250kDa | 0.0341728 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0332641 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0332044 |
| KIF16B | kinesin family member 16B | 0.0305326 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0298021 |
| KRT19 | keratin 19, type I | 0.0269665 |
| GSE1 | Gse1 coiled-coil protein | 0.0264268 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0263354 |
| FLNA | filamin A, alpha | 0.02626 |
| WAC | WW domain containing adaptor with coiled-coil | 0.025714 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0256293 |
| TOB1 | transducer of ERBB2, 1 | 0.0253717 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0248299 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0241566 |
| EGR1 | early growth response 1 | 0.0237867 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0237203 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0236332 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0232403 |
| CCNY | cyclin Y | 0.0231499 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0228555 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0223937 |
| KIAA1217 | KIAA1217 | 0.0222631 |
| PGK1 | phosphoglycerate kinase 1 | 0.0220239 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0217705 |
| FADS2 | fatty acid desaturase 2 | 0.0216141 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0214214 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0211731 |
| SHROOM3 | shroom family member 3 | 0.0211258 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0210948 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0210427 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0206966 |
| YAP1 | Yes-associated protein 1 | 0.0202351 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0201168 |
| INSIG1 | insulin induced gene 1 | 0.020001 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.019738 |
| TMEM165 | transmembrane protein 165 | 0.01971 |
| ACTN4 | actinin, alpha 4 | 0.0196802 |
| FAM13A | family with sequence similarity 13, member A | 0.0195465 |
| JUP | junction plakoglobin | 0.0191112 |
| MKRN1 | makorin ring finger protein 1 | 0.0191028 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0185602 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0184002 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0181794 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0181688 |
| B2M | beta-2-microglobulin | 0.0178923 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0178917 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0178482 |
| LDLR | low density lipoprotein receptor | 0.0177859 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0177748 |
| SF1 | splicing factor 1 | 0.0176714 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0175417 |
| TMEM41B | transmembrane protein 41B | 0.01743 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0172664 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.017077 |
| PLEC | plectin | 0.0169683 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0169636 |
| PCGF2 | polycomb group ring finger 2 | 0.0166849 |
| TPCN1 | two pore segment channel 1 | 0.0166508 |
| MYADM | myeloid-associated differentiation marker | 0.0165973 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0165274 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0164146 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0163092 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0163019 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0161793 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0160925 |
| YEATS2 | YEATS domain containing 2 | 0.016066 |
| PLXNB2 | plexin B2 | 0.0160595 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0159732 |
| TPD52 | tumor protein D52 | 0.0159611 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0158015 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0156747 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0155786 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0153915 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) | 0.0152271 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.130741 |
| RPL19 | ribosomal protein L19 | -0.122022 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.103398 |
| CDK12 | cyclin-dependent kinase 12 | -0.0902066 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0894764 |
| AHNAK | AHNAK nucleoprotein | -0.0634774 |
| PTMA | prothymosin, alpha | -0.0620721 |
| TMSB10 | thymosin beta 10 | -0.060034 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0543807 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0527088 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0511787 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0509203 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0478873 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.045909 |
| ACACA | acetyl-CoA carboxylase alpha | -0.044851 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0443052 |
| TMSB4X | thymosin beta 4, X-linked | -0.0430333 |
| ZNF217 | zinc finger protein 217 | -0.0429291 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0419857 |
| CCNI | cyclin I | -0.0410381 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.041018 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0406829 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0403896 |
| TC2N | tandem C2 domains, nuclear | -0.0402821 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0402009 |
| CANX | calnexin | -0.0396566 |
| SMYD3 | SET and MYND domain containing 3 | -0.0384367 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0383636 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0381554 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0377653 |
| NTN4 | netrin 4 | -0.0369061 |
| SLFN5 | schlafen family member 5 | -0.0368008 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.035815 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0344273 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0340314 |
| NCOA7 | nuclear receptor coactivator 7 | -0.033905 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0331608 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0329201 |
| MYO6 | myosin VI | -0.0327158 |
| RPL23 | ribosomal protein L23 | -0.03185 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0306112 |
| RPS24 | ribosomal protein S24 | -0.0302782 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0295557 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0291176 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0283753 |
| RPS3 | ribosomal protein S3 | -0.0281713 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0279274 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.027704 |
| IER3 | immediate early response 3 | -0.0275929 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0275905 |
| DUSP16 | dual specificity phosphatase 16 | -0.0275158 |
| NF1 | neurofibromin 1 | -0.0269025 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0267533 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0263075 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0262707 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0259234 |
| RESF1 | retroelement silencing factor 1 | -0.0254962 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0252456 |
| SERINC3 | serine incorporator 3 | -0.0251116 |
| VIM | vimentin | -0.0250002 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0246805 |
| TMC5 | transmembrane channel-like 5 | -0.0245547 |
| EXOC4 | exocyst complex component 4 | -0.0244585 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0239375 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0238246 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0236454 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0233113 |
| OSMR | oncostatin M receptor | -0.0232085 |
| RPS8 | ribosomal protein S8 | -0.0230709 |
| RPL35A | ribosomal protein L35a | -0.0227874 |
| RAB10 | RAB10, member RAS oncogene family | -0.0227786 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0227545 |
| MAP4 | microtubule-associated protein 4 | -0.022539 |
| RPL31 | ribosomal protein L31 | -0.0223974 |
| DSPP | dentin sialophosphoprotein | -0.0222318 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0221382 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0219282 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0218758 |
| YBX1 | Y box binding protein 1 | -0.0217511 |
| STK4 | serine/threonine kinase 4 | -0.0216596 |
| PARP1 | poly (ADP-ribose) polymerase 1 | -0.0215487 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0213883 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.02138 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0213638 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0212845 |
| TXNRD1 | thioredoxin reductase 1 | -0.0209907 |
| PARD3 | par-3 family cell polarity regulator | -0.0209318 |
| S100A9 | S100 calcium binding protein A9 | -0.0208816 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0208407 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0208026 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0205566 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.020445 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0203966 |
| SETX | senataxin | -0.0203401 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0202357 |
| FOXP1 | forkhead box P1 | -0.0200792 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0197959 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0197954 |
| OLA1 | Obg-like ATPase 1 | -0.0197467 |
| MYOF | myoferlin | -0.0196593 |
