Glycyrrhizic acid_C32 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Glycyrrhizic acid perturbation in C32 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Glycyrrhizic acid_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.138132
CDC73 cell division cycle 73 0.122307
NAMPT nicotinamide phosphoribosyltransferase 0.119248
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.112373
KMT2E lysine (K)-specific methyltransferase 2E 0.0749119
NUP58 nucleoporin 58 0.065968
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0659075
CD109 CD109 molecule 0.0658242
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0626964
ESYT2 extended synaptotagmin-like protein 2 0.0615552
RNF145 ring finger protein 145 0.0567147
RBM33 RNA binding motif protein 33 0.0551038
HELZ helicase with zinc finger 0.0517709
EPS8 epidermal growth factor receptor pathway substrate 8 0.0493919
LEF1 lymphoid enhancer-binding factor 1 0.0473365
FNDC3B fibronectin type III domain containing 3B 0.0455563
ZNF292 zinc finger protein 292 0.0446508
UBE2H ubiquitin-conjugating enzyme E2H 0.0446055
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0436056
PKM pyruvate kinase, muscle 0.0417203
CCNL1 cyclin L1 0.0412016
COG5 component of oligomeric golgi complex 5 0.0408868
ICAM1 intercellular adhesion molecule 1 0.0405747
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0403667
SPRED1 sprouty-related, EVH1 domain containing 1 0.0385739
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.037029
BHLHE40 basic helix-loop-helix family, member e40 0.0369526
CPEB2 cytoplasmic polyadenylation element binding protein 2 0.0360448
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0350084
DSCAM Down syndrome cell adhesion molecule 0.0341287
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0340348
MRTFA myocardin related transcription factor A 0.0332015
FOXJ3 forkhead box J3 0.0325145
FBXO7 F-box protein 7 0.0323533
COPA coatomer protein complex, subunit alpha 0.0318921
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0313103
WDR43 WD repeat domain 43 0.0311792
KMT2C lysine (K)-specific methyltransferase 2C 0.0310779
TNPO3 transportin 3 0.0305988
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0300424
UHMK1 U2AF homology motif (UHM) kinase 1 0.0297617
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0296886
TNNC1 troponin C type 1 (slow) 0.0294022
PI15 peptidase inhibitor 15 0.0293815
RTN4 reticulon 4 0.0291643
CNOT4 CCR4-NOT transcription complex, subunit 4 0.0289126
FYN FYN proto-oncogene, Src family tyrosine kinase 0.0288782
NBAS neuroblastoma amplified sequence 0.0288612
NEK7 NIMA-related kinase 7 0.0282969
PUM2 pumilio RNA-binding family member 2 0.0278545
FN1 fibronectin 1 0.0272295
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.026688
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0264488
LOC112694756 uncharaterized LOC112694756 0.0261787
PGK1 phosphoglycerate kinase 1 0.026077
TENT4A terminal nucleotidyltransferase 4A 0.0259091
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.025846
EEF2 eukaryotic translation elongation factor 2 0.0255889
KDM6A lysine (K)-specific demethylase 6A 0.02553
ATP13A3 ATPase type 13A3 0.0246989
EEF1G eukaryotic translation elongation factor 1 gamma 0.0246254
STOM stomatin 0.024264
USP3 ubiquitin specific peptidase 3 0.0241302
HOOK2 hook microtubule-tethering protein 2 0.0230215
CUL3 cullin 3 0.0229962
APP amyloid beta (A4) precursor protein 0.0227557
ARRDC3 arrestin domain containing 3 0.0226672
PUM1 pumilio RNA-binding family member 1 0.0225357
CDK19 cyclin-dependent kinase 19 0.0220402
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0219965
SRPK2 SRSF protein kinase 2 0.021879
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0217154
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.0215955
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0215157
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.021319
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0212473
FOSL1 FOS-like antigen 1 0.0211932
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0211746
NT5C3A 5'-nucleotidase, cytosolic IIIA 0.020991
FTH1 ferritin, heavy polypeptide 1 0.0209865
SETD5 SET domain containing 5 0.0209855
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0207104
MKRN1 makorin ring finger protein 1 0.0206483
VGLL4 vestigial-like family member 4 0.0206153
CD59 CD59 molecule, complement regulatory protein 0.0205617
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.020122
RICTOR RPTOR independent companion of MTOR, complex 2 0.0200164
ARL8B ADP-ribosylation factor-like 8B 0.0198742
WAC WW domain containing adaptor with coiled-coil 0.0198262
MTPN myotrophin 0.0197255
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.0194882
DENND5A DENN/MADD domain containing 5A 0.0194477
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0193213
RAB1A RAB1A, member RAS oncogene family 0.0192779
XPO1 exportin 1 0.0191144
FXR1 fragile X mental retardation, autosomal homolog 1 0.0189955
MED13L mediator complex subunit 13-like 0.0186271
RAP1B RAP1B, member of RAS oncogene family 0.0185977
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0184317
CSDE1 cold shock domain containing E1, RNA-binding 0.0182665

decreased expression

Symbol Name Standardized Value
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.232944
NLGN1 neuroligin 1 -0.229755
IGFBP5 insulin-like growth factor binding protein 5 -0.199576
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.185127
GPC6 glypican 6 -0.176547
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 -0.141391
VGF VGF nerve growth factor inducible -0.108484
VIM vimentin -0.105394
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0986674
ASPH aspartate beta-hydroxylase -0.0904588
AKAP12 A kinase (PRKA) anchor protein 12 -0.0898752
MACROD2 MACRO domain containing 2 -0.0875998
FMN1 formin 1 -0.0866151
NAV3 neuron navigator 3 -0.0762346
FRMD4A FERM domain containing 4A -0.0744753
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0726734
IFI16 interferon, gamma-inducible protein 16 -0.071105
EHBP1 EH domain binding protein 1 -0.0707499
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0691041
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0679825
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0665329
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0663347
PCDH7 protocadherin 7 -0.065471
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0641645
NPAS2 neuronal PAS domain protein 2 -0.0630289
TMSB10 thymosin beta 10 -0.0620827
CTTNBP2 cortactin binding protein 2 -0.0606034
DST dystonin -0.0575115
CUX1 cut-like homeobox 1 -0.0554002
CENPF centromere protein F, 350/400kDa -0.0552457
MAML3 mastermind-like 3 (Drosophila) -0.0548694
IGFBP3 insulin-like growth factor binding protein 3 -0.0524309
PTPRD protein tyrosine phosphatase, receptor type, D -0.0523412
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0520208
RRBP1 ribosome binding protein 1 -0.0519456
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.0515747
AHNAK AHNAK nucleoprotein -0.051376
HLA-B major histocompatibility complex, class I, B -0.05043
MMP16 matrix metallopeptidase 16 (membrane-inserted) -0.0496019
SCFD2 sec1 family domain containing 2 -0.0494605
CALD1 caldesmon 1 -0.0489375
CDK14 cyclin-dependent kinase 14 -0.0482769
NAV1 neuron navigator 1 -0.0482346
LRMDA leucine rich melanocyte differentiation associated -0.0472451
EXOC4 exocyst complex component 4 -0.0464909
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0459673
COL19A1 collagen, type XIX, alpha 1 -0.0448583
LINGO2 leucine rich repeat and Ig domain containing 2 -0.0436739
SOX5 SRY (sex determining region Y)-box 5 -0.042717
NEGR1 neuronal growth regulator 1 -0.0414968
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0404246
TBC1D22A TBC1 domain family, member 22A -0.0400154
HMGA2 high mobility group AT-hook 2 -0.0395937
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0392803
ZBTB20 zinc finger and BTB domain containing 20 -0.0387183
RUNX1 runt-related transcription factor 1 -0.0386297
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.038472
HMCN1 hemicentin 1 -0.038302
PTK2 protein tyrosine kinase 2 -0.0381027
ZNF704 zinc finger protein 704 -0.0380278
PDIA4 protein disulfide isomerase family A, member 4 -0.0375343
RAD51B RAD51 paralog B -0.0370622
OXR1 oxidation resistance 1 -0.0366418
PRELID2 PRELI domain containing 2 -0.0358931
TAS2R14 taste receptor, type 2, member 14 -0.0356538
LSAMP limbic system-associated membrane protein -0.0354612
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0352122
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0348326
LAMB1 laminin, beta 1 -0.0341418
CALU calumenin -0.0339794
NPC1 Niemann-Pick disease, type C1 -0.0335381
FBXL7 F-box and leucine-rich repeat protein 7 -0.0328271
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -0.0326962
CANX calnexin -0.0322174
LMNA lamin A/C -0.0320797
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0319425
NRCAM neuronal cell adhesion molecule -0.0316752
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) -0.0314709
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0310232
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0306777
FMNL2 formin-like 2 -0.0304736
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.03042
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0303908
PDE10A phosphodiesterase 10A -0.0302637
KIRREL1 kirre like nephrin family adhesion molecule 1 -0.0295327
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0295264
S100A6 S100 calcium binding protein A6 -0.0295097
PTMA prothymosin, alpha -0.0295048
IER3 immediate early response 3 -0.0295043
HILPDA hypoxia inducible lipid droplet-associated -0.0290184
PARVB parvin, beta -0.028629
AKAP9 A kinase (PRKA) anchor protein 9 -0.0285767
PLIN2 perilipin 2 -0.0284188
PTCHD4 patched domain containing 4 -0.0281104
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0276542
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0276176
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0273327
ZMYND8 zinc finger, MYND-type containing 8 -0.0267204
BACE2 beta-site APP-cleaving enzyme 2 -0.0266713
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.0265979