Glycyrrhizic acid_CHP-212 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Glycyrrhizic acid perturbation in CHP-212 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Glycyrrhizic acid_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.108437
HELZ helicase with zinc finger 0.0642932
FAM13A family with sequence similarity 13, member A 0.0507828
EEF1G eukaryotic translation elongation factor 1 gamma 0.0506356
FMN1 formin 1 0.0440628
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0333962
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0320097
PGK1 phosphoglycerate kinase 1 0.0301312
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0275145
ZMYM2 zinc finger, MYM-type 2 0.0272665
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0271377
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.026961
MAP1B microtubule-associated protein 1B 0.0262832
BIRC6 baculoviral IAP repeat containing 6 0.0257057
NPEPPS aminopeptidase puromycin sensitive 0.0253524
NUP58 nucleoporin 58 0.0252417
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0252416
NAMPT nicotinamide phosphoribosyltransferase 0.0247574
EEF2 eukaryotic translation elongation factor 2 0.0245346
PDIA3 protein disulfide isomerase family A, member 3 0.0243939
PKM pyruvate kinase, muscle 0.0242416
MMP2 matrix metallopeptidase 2 0.0240719
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.0236896
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.0236765
PUM2 pumilio RNA-binding family member 2 0.023031
ZNF292 zinc finger protein 292 0.0230282
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0230019
FNDC3B fibronectin type III domain containing 3B 0.0227873
USP36 ubiquitin specific peptidase 36 0.0221521
SPAG9 sperm associated antigen 9 0.0219666
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0218116
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.0215915
ADGRG6 adhesion G protein-coupled receptor G6 0.0210253
WAC WW domain containing adaptor with coiled-coil 0.0210015
XPO1 exportin 1 0.020778
CCNY cyclin Y 0.0205505
HMGB2 high mobility group box 2 0.0205361
CDC27 cell division cycle 27 0.0204187
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0198852
ITPRID2 ITPR interacting domain containing 2 0.0196445
CHD1 chromodomain helicase DNA binding protein 1 0.0195626
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0192428
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.0192195
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0191814
CCNL1 cyclin L1 0.0185123
BRWD1 bromodomain and WD repeat domain containing 1 0.0183889
FOXO3 forkhead box O3 0.0181764
CASC3 cancer susceptibility candidate 3 0.0179831
FLNA filamin A, alpha 0.0178994
NKTR natural killer cell triggering receptor 0.017836
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0175829
FXR1 fragile X mental retardation, autosomal homolog 1 0.0175116
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0174965
FAM13B family with sequence similarity 13, member B 0.017417
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0172763
KIRREL1 kirre like nephrin family adhesion molecule 1 0.0172487
AOPEP aminopeptidase O (putative) 0.0171855
PCM1 pericentriolar material 1 0.0169359
QKI QKI, KH domain containing, RNA binding 0.016861
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.0166971
TCERG1 transcription elongation regulator 1 0.016695
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0165455
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0164186
KDM6A lysine (K)-specific demethylase 6A 0.0163507
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.0163501
RNF24 ring finger protein 24 0.0162837
RPL4 ribosomal protein L4 0.016247
NCOR1 nuclear receptor corepressor 1 0.0161383
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0160894
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 0.0159867
PRPF8 pre-mRNA processing factor 8 0.0159411
CLTC clathrin, heavy chain (Hc) 0.0157832
RFX7 regulatory factor X, 7 0.0157664
COG5 component of oligomeric golgi complex 5 0.0157326
BCLAF1 BCL2-associated transcription factor 1 0.0156879
RSRC2 arginine/serine-rich coiled-coil 2 0.0156487
DSCAM Down syndrome cell adhesion molecule 0.0154705
VAT1 vesicle amine transport 1 0.0153953
YTHDC1 YTH domain containing 1 0.0153578
ZNF148 zinc finger protein 148 0.0151912
PNISR PNN-interacting serine/arginine-rich protein 0.0151015
FRMD6 FERM domain containing 6 0.0149914
ARGLU1 arginine and glutamate rich 1 0.0149429
TNRC6A trinucleotide repeat containing 6A 0.0149194
TRAM1 translocation associated membrane protein 1 0.0148955
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.014854
TBK1 TANK-binding kinase 1 0.0148074
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0147607
RBM33 RNA binding motif protein 33 0.0147532
WDPCP WD repeat containing planar cell polarity effector 0.0147449
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0147386
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.0147256
CENPE centromere protein E, 312kDa 0.0146841
NUP54 nucleoporin 54kDa 0.0144512
KMT2C lysine (K)-specific methyltransferase 2C 0.0144062
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.0143765
TET2 tet methylcytosine dioxygenase 2 0.0143217
ANKRD12 ankyrin repeat domain 12 0.0142443
JPT1 Jupiter microtubule associated homolog 1 0.014198
ATXN2L ataxin 2-like 0.014138

decreased expression

Symbol Name Standardized Value
NRG1 neuregulin 1 -0.124711
LSAMP limbic system-associated membrane protein -0.103859
AKAP12 A kinase (PRKA) anchor protein 12 -0.0967556
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -0.0924009
VCL vinculin -0.0862337
NALF1 NALCN channel auxiliary factor 1 -0.0857784
VIM vimentin -0.08139
EXT1 exostosin glycosyltransferase 1 -0.0809384
IGF2 insulin-like growth factor 2 -0.0733009
ACTG1 actin gamma 1 -0.0702628
PTPRD protein tyrosine phosphatase, receptor type, D -0.0680461
EFNA5 ephrin-A5 -0.0548322
PTMA prothymosin, alpha -0.0543385
THSD4 thrombospondin, type I, domain containing 4 -0.0524223
RPS6 ribosomal protein S6 -0.0509529
RPS24 ribosomal protein S24 -0.0496205
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.049545
IER3 immediate early response 3 -0.0482587
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 -0.0451674
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0448942
SYT1 synaptotagmin I -0.0446642
BPTF bromodomain PHD finger transcription factor -0.0435265
RPL11 ribosomal protein L11 -0.0433477
TPT1 tumor protein, translationally-controlled 1 -0.043225
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0431533
BCAS3 breast carcinoma amplified sequence 3 -0.0426701
RPS8 ribosomal protein S8 -0.0396027
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0390681
CUX1 cut-like homeobox 1 -0.0386649
NPAS2 neuronal PAS domain protein 2 -0.0374736
RPL35A ribosomal protein L35a -0.036645
ZBTB20 zinc finger and BTB domain containing 20 -0.0351995
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.034919
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 -0.0344406
TMSB10 thymosin beta 10 -0.0342128
MACF1 microtubule-actin crosslinking factor 1 -0.0335514
RPL31 ribosomal protein L31 -0.0334579
RPL38 ribosomal protein L38 -0.0330109
RPS25 ribosomal protein S25 -0.0323763
KLHL13 kelch-like family member 13 -0.0322218
PDLIM5 PDZ and LIM domain 5 -0.0320446
ZNF804A zinc finger protein 804A -0.0320365
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0311954
ASPH aspartate beta-hydroxylase -0.0310725
DLC1 DLC1 Rho GTPase activating protein -0.0309109
RPLP1 ribosomal protein, large, P1 -0.0307014
PDE10A phosphodiesterase 10A -0.0305371
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0297892
MCL1 myeloid cell leukemia 1 -0.0296834
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.0296468
CEMIP cell migration inducing protein, hyaluronan binding -0.0295623
GCC2 GRIP and coiled-coil domain containing 2 -0.0295044
BICD1 bicaudal D homolog 1 (Drosophila) -0.0293448
AHNAK AHNAK nucleoprotein -0.0286985
RPS12 ribosomal protein S12 -0.0286679
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0281741
SLIT2 slit homolog 2 (Drosophila) -0.0279169
RPL19 ribosomal protein L19 -0.0278807
LOC102724023 ES1 protein homolog, mitochondrial -0.0278566
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0275358
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0275052
COL4A5 collagen, type IV, alpha 5 -0.0273187
RIGI RNA sensor RIG-I -0.026709
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.025713
KPNB1 karyopherin (importin) beta 1 -0.0257105
LINGO2 leucine rich repeat and Ig domain containing 2 -0.025419
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0254063
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0253523
CANX calnexin -0.0252979
NREP neuronal regeneration related protein -0.0251964
MAPK10 mitogen-activated protein kinase 10 -0.0250336
SP100 SP100 nuclear antigen -0.0250287
TBC1D22A TBC1 domain family, member 22A -0.0250121
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0250109
PARD3 par-3 family cell polarity regulator -0.0249873
TRIM24 tripartite motif containing 24 -0.0249574
RPL26 ribosomal protein L26 -0.024885
MYO1E myosin IE -0.0248378
TPM1 tropomyosin 1 (alpha) -0.0246373
RPS29 ribosomal protein S29 -0.0245278
RSL1D1 ribosomal L1 domain containing 1 -0.0244648
DHRSX dehydrogenase/reductase (SDR family) X-linked -0.0242328
RNF213 ring finger protein 213 -0.0241884
TM4SF1 transmembrane 4 L six family member 1 -0.024121
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0241082
DNM3 dynamin 3 -0.0234475
HM13 histocompatibility (minor) 13 -0.0233608
RPL34 ribosomal protein L34 -0.0233582
PTPRK protein tyrosine phosphatase, receptor type, K -0.0231201
TPM4 tropomyosin 4 -0.0229962
DIAPH2 diaphanous-related formin 2 -0.0228599
KIF26B kinesin family member 26B -0.0223532
COL1A1 collagen, type I, alpha 1 -0.0221297
RPTOR regulatory associated protein of MTOR, complex 1 -0.0221149
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0220311
CDH13 cadherin 13 -0.0219413
GPATCH2L G patch domain containing 2-like -0.0218853
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0214238
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0211291
FBXO11 F-box protein 11 -0.0210754