Glycyrrhizic acid_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Glycyrrhizic acid perturbation in COLO 205 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Glycyrrhizic acid_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0812075
PKM pyruvate kinase, muscle 0.0795116
FTH1 ferritin, heavy polypeptide 1 0.0787198
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0688483
SRRM2 serine/arginine repetitive matrix 2 0.0662876
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.0632517
PADI1 peptidyl arginine deiminase, type I 0.0600589
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0590159
PDIA3 protein disulfide isomerase family A, member 3 0.0582976
CCNL1 cyclin L1 0.0580156
EGR1 early growth response 1 0.0537871
TXNIP thioredoxin interacting protein 0.0488375
CD68 CD68 molecule 0.0477655
N4BP2L2 NEDD4 binding protein 2-like 2 0.0445318
NDRG1 N-myc downstream regulated 1 0.0441128
DSCAM Down syndrome cell adhesion molecule 0.0439826
SFTPA2 surfactant protein A2 0.0401919
ARHGAP26 Rho GTPase activating protein 26 0.0399237
EEF1G eukaryotic translation elongation factor 1 gamma 0.0381758
LMO7 LIM domain 7 0.0373319
ARGLU1 arginine and glutamate rich 1 0.0372974
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.0357466
MUC13 mucin 13, cell surface associated 0.03518
NCOR2 nuclear receptor corepressor 2 0.03481
EFNB2 ephrin-B2 0.0346978
FAT1 FAT atypical cadherin 1 0.0329061
ANXA2 annexin A2 0.0316401
APLP2 amyloid beta (A4) precursor-like protein 2 0.0311599
EGLN3 egl-9 family hypoxia-inducible factor 3 0.0306202
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0305172
PGK1 phosphoglycerate kinase 1 0.0295114
FNDC3B fibronectin type III domain containing 3B 0.0292834
KDM4C lysine (K)-specific demethylase 4C 0.0290994
JUP junction plakoglobin 0.0288023
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0283758
FOSL2 FOS-like antigen 2 0.0274446
RNASEH2A ribonuclease H2, subunit A 0.0270373
SREBF2 sterol regulatory element binding transcription factor 2 0.0269846
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0263024
TSC22D1 TSC22 domain family, member 1 0.0257779
MYH9 myosin, heavy chain 9, non-muscle 0.0256422
CDHR2 cadherin-related family member 2 0.0251292
SH3PXD2A SH3 and PX domains 2A 0.0245436
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0243071
INTS6 integrator complex subunit 6 0.0240535
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.0238856
SEC23B Sec23 homolog B (S. cerevisiae) 0.0236079
BCLAF1 BCL2-associated transcription factor 1 0.0231306
LOC112694756 uncharaterized LOC112694756 0.0231015
PDZD8 PDZ domain containing 8 0.0225608
HELZ2 helicase with zinc finger 2, transcriptional coactivator 0.0225175
SCARB1 scavenger receptor class B, member 1 0.0220329
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0219322
AFF1 AF4/FMR2 family, member 1 0.0218472
PHF3 PHD finger protein 3 0.0218467
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0218137
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0217358
ZSWIM6 zinc finger, SWIM-type containing 6 0.0216866
BRD2 bromodomain containing 2 0.0215576
KIF16B kinesin family member 16B 0.0214953
MYO5B myosin VB 0.0212086
BICRAL BICRA like chromatin remodeling complex associated protein 0.0208814
LDHA lactate dehydrogenase A 0.0204483
CEMIP2 cell migration inducing hyaluronidase 2 0.0204313
SMAD3 SMAD family member 3 0.0204001
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.0203275
PLXNB2 plexin B2 0.0199177
VEGFA vascular endothelial growth factor A 0.019873
USP8 ubiquitin specific peptidase 8 0.0198393
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3 0.0198153
TMEM63A transmembrane protein 63A 0.0197712
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.0197703
SCFD1 sec1 family domain containing 1 0.0197121
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 0.0196703
HLA-A major histocompatibility complex, class I, A 0.0194814
CLDN7 claudin 7 0.0194666
MCL1 myeloid cell leukemia 1 0.0194389
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0191914
CNOT3 CCR4-NOT transcription complex, subunit 3 0.0191765
SEC16A SEC16 homolog A (S. cerevisiae) 0.0190751
LENG8 leukocyte receptor cluster (LRC) member 8 0.019052
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 0.0190383
ECE1 endothelin converting enzyme 1 0.0188883
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.0186404
TXNDC11 thioredoxin domain containing 11 0.0185421
BHLHE40 basic helix-loop-helix family, member e40 0.0183875
STAT2 signal transducer and activator of transcription 2, 113kDa 0.0183485
MXD1 MAX dimerization protein 1 0.0183447
IRF1 interferon regulatory factor 1 0.0181209
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.0181038
DIAPH1 diaphanous-related formin 1 0.0180696
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.0180326
POU2F2 POU class 2 homeobox 2 0.0180173
IRS2 insulin receptor substrate 2 0.0180057
CLDN4 claudin 4 0.0179645
MLPH melanophilin 0.0178885
ZNF652 zinc finger protein 652 0.0178802
WNK1 WNK lysine deficient protein kinase 1 0.017814
NUP58 nucleoporin 58 0.0177735
DSCAML1 Down syndrome cell adhesion molecule like 1 0.0177186

decreased expression

Symbol Name Standardized Value
TPT1 tumor protein, translationally-controlled 1 -0.203196
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.162083
PTMA prothymosin, alpha -0.139008
LYZ lysozyme -0.074212
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0672782
CANX calnexin -0.0625365
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0605448
AHNAK AHNAK nucleoprotein -0.0591722
FTL ferritin, light polypeptide -0.0570026
TMSB10 thymosin beta 10 -0.0559356
SPATA13 spermatogenesis associated 13 -0.0553981
PERP PERP, TP53 apoptosis effector -0.0553411
RNF149 ring finger protein 149 -0.0549157
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0547487
RPS24 ribosomal protein S24 -0.0547327
KDM3A lysine (K)-specific demethylase 3A -0.0530875
GOLGB1 golgin B1 -0.0488788
XAF1 XIAP associated factor 1 -0.0474246
EPSTI1 epithelial stromal interaction 1 (breast) -0.0471404
NCOA7 nuclear receptor coactivator 7 -0.047042
ASPH aspartate beta-hydroxylase -0.0455979
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0448624
RRBP1 ribosome binding protein 1 -0.0442202
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0436665
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0435411
GOLGA4 golgin A4 -0.0430853
STAT1 signal transducer and activator of transcription 1, 91kDa -0.042592
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0425193
ABLIM1 actin binding LIM protein 1 -0.0419095
H1-0 H1.0 linker histone -0.0403731
JMJD1C jumonji domain containing 1C -0.0403579
GCLC glutamate-cysteine ligase, catalytic subunit -0.039979
NPEPPS aminopeptidase puromycin sensitive -0.0379928
KPNB1 karyopherin (importin) beta 1 -0.0376039
DLG1 discs, large homolog 1 (Drosophila) -0.0369224
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0367666
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0364396
RPL7L1 ribosomal protein L7-like 1 -0.0361125
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.035885
VCL vinculin -0.035838
EPCAM epithelial cell adhesion molecule -0.035473
PRELID2 PRELI domain containing 2 -0.0351941
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0347373
EPHB2 EPH receptor B2 -0.0345595
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease -0.0344734
RSRC2 arginine/serine-rich coiled-coil 2 -0.0344595
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0341667
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0340293
SKP1 S-phase kinase-associated protein 1 -0.0334365
RBM39 RNA binding motif protein 39 -0.0331326
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 -0.0327368
KLF6 Kruppel-like factor 6 -0.0327084
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0327038
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0325421
HLA-B major histocompatibility complex, class I, B -0.0322332
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0320884
SEC31A SEC31 homolog A (S. cerevisiae) -0.031887
RPL12 ribosomal protein L12 -0.0318593
OGA O-GlcNAcase -0.0318366
RAD21 RAD21 homolog (S. pombe) -0.0318349
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0318008
SLC38A1 solute carrier family 38, member 1 -0.0316701
TPR translocated promoter region, nuclear basket protein -0.0315659
PARP4 poly (ADP-ribose) polymerase family, member 4 -0.0311681
NAMPT nicotinamide phosphoribosyltransferase -0.0311135
TMEM87A transmembrane protein 87A -0.0310901
SAMD12 sterile alpha motif domain containing 12 -0.0303405
MKI67 marker of proliferation Ki-67 -0.0303289
ACBD3 acyl-CoA binding domain containing 3 -0.0300193
RPS8 ribosomal protein S8 -0.0299242
MX2 MX dynamin-like GTPase 2 -0.0297326
PDE4D phosphodiesterase 4D, cAMP-specific -0.0297127
NIPBL Nipped-B homolog (Drosophila) -0.0296117
SBF2 SET binding factor 2 -0.0295234
ENSA endosulfine alpha -0.0294386
PDIA4 protein disulfide isomerase family A, member 4 -0.029402
PARD3 par-3 family cell polarity regulator -0.0291873
ITGA6 integrin, alpha 6 -0.0291708
RIGI RNA sensor RIG-I -0.029058
GCC2 GRIP and coiled-coil domain containing 2 -0.0288924
MATR3 matrin 3 -0.0287875
DSTN destrin (actin depolymerizing factor) -0.02872
BPTF bromodomain PHD finger transcription factor -0.0285796
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.0285196
KLF5 Kruppel-like factor 5 (intestinal) -0.0284761
HMGB1 high mobility group box 1 -0.0283814
H3-3B H3.3 histone B -0.028259
SP100 SP100 nuclear antigen -0.028005
BRCA2 breast cancer 2, early onset -0.0276864
BTBD9 BTB (POZ) domain containing 9 -0.0275915
MXI1 MAX interactor 1, dimerization protein -0.0271776
RPL34 ribosomal protein L34 -0.0271212
NF1 neurofibromin 1 -0.0269177
GMDS GDP-mannose 4,6-dehydratase -0.0269064
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.026882
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0268186
EZR ezrin -0.0267557
PIBF1 progesterone immunomodulatory binding factor 1 -0.0267474
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0266236
ARHGAP5 Rho GTPase activating protein 5 -0.0265267