| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Glycyrrhizic acid_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0657147 |
| HMGA1 | high mobility group AT-hook 1 | 0.0520281 |
| RPL35A | ribosomal protein L35a | 0.0446071 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0386644 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0316819 |
| CCNL1 | cyclin L1 | 0.0228573 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0196986 |
| FNDC3B | fibronectin type III domain containing 3B | 0.019319 |
| KRT19 | keratin 19, type I | 0.0183514 |
| PFN1 | profilin 1 | 0.0181005 |
| FLNA | filamin A, alpha | 0.0162798 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.0161193 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0152041 |
| TCERG1 | transcription elongation regulator 1 | 0.0147887 |
| WDR43 | WD repeat domain 43 | 0.0147439 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0145724 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0126245 |
| S100A4 | S100 calcium binding protein A4 | 0.0125665 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0121554 |
| FAM120A | family with sequence similarity 120A | 0.011887 |
| AGRN | agrin | 0.0117031 |
| LRRC58 | leucine rich repeat containing 58 | 0.0117006 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0115488 |
| LAMA4 | laminin, alpha 4 | 0.0114962 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0113776 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.01116 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0109863 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0108151 |
| VKORC1L1 | vitamin K epoxide reductase complex, subunit 1-like 1 | 0.0105998 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0104423 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.010365 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0103384 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0103379 |
| RASA2 | RAS p21 protein activator 2 | 0.0102984 |
| FLII | flightless I homolog (Drosophila) | 0.0102487 |
| JUP | junction plakoglobin | 0.0102243 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0101491 |
| RPN1 | ribophorin I | 0.0101409 |
| MYADM | myeloid-associated differentiation marker | 0.0101403 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0100518 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0100393 |
| NDRG1 | N-myc downstream regulated 1 | 0.0100371 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00999276 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa | 0.00976198 |
| RPS26 | ribosomal protein S26 | 0.00972067 |
| USP3 | ubiquitin specific peptidase 3 | 0.0096176 |
| ADNP | activity-dependent neuroprotector homeobox | 0.00954548 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.0093976 |
| USP36 | ubiquitin specific peptidase 36 | 0.00913373 |
| PDGFC | platelet derived growth factor C | 0.00912231 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.00906024 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.00905545 |
| HMGA2 | high mobility group AT-hook 2 | 0.00868773 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.00868444 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.00861468 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.00860595 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0085774 |
| LAMA5 | laminin, alpha 5 | 0.00857658 |
| GOLGA8A | golgin A8 family, member A | 0.00852325 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00851134 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00848886 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00847479 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00837039 |
| NEK6 | NIMA-related kinase 6 | 0.00830226 |
| NAA25 | N(alpha)-acetyltransferase 25, NatB auxiliary subunit | 0.00823974 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.00816058 |
| ATN1 | atrophin 1 | 0.00815991 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.00802594 |
| UBQLN1 | ubiquilin 1 | 0.00794345 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.00790936 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00787333 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00785218 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.00777792 |
| CDCP1 | CUB domain containing protein 1 | 0.00773093 |
| RPL13A | ribosomal protein L13a | 0.00766292 |
| ANK2 | ankyrin 2, neuronal | 0.00765759 |
| MACROH2A1 | macroH2A.1 histone | 0.00763353 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | 0.0076297 |
| JAG1 | jagged 1 | 0.00758041 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.00755227 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.00755173 |
| ANKRD12 | ankyrin repeat domain 12 | 0.00750314 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.00743825 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00742206 |
| PCBP1 | poly(rC) binding protein 1 | 0.00741226 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00740234 |
| KXD1 | KxDL motif containing 1 | 0.00737196 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.00736386 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00731307 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00727591 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00720987 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.00713684 |
| TIMM23B | translocase of inner mitochondrial membrane 23 homolog B (yeast) | 0.00713402 |
| WASF2 | WAS protein family, member 2 | 0.00705507 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | 0.00701943 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.00700296 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.00696947 |
| SFTPA2 | surfactant protein A2 | 0.00692714 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.00689844 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00684521 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.123152 |
| ASPH | aspartate beta-hydroxylase | -0.123117 |
| AHNAK | AHNAK nucleoprotein | -0.120236 |
| UBC | ubiquitin C | -0.108152 |
| ENO1 | enolase 1, (alpha) | -0.0920987 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0920727 |
| FTL | ferritin, light polypeptide | -0.0911031 |
| PTMA | prothymosin, alpha | -0.0908254 |
| RPS27A | ribosomal protein S27a | -0.0902523 |
| APP | amyloid beta (A4) precursor protein | -0.087306 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0774341 |
| TMSB10 | thymosin beta 10 | -0.0689908 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0678506 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0647059 |
| CANX | calnexin | -0.0630119 |
| SET | SET nuclear proto-oncogene | -0.0589704 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0542346 |
| PCBP2 | poly(rC) binding protein 2 | -0.0535401 |
| TXNRD1 | thioredoxin reductase 1 | -0.0513527 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0492193 |
| OGA | O-GlcNAcase | -0.0465406 |
| RPL23 | ribosomal protein L23 | -0.0459659 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0455771 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0449899 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0449312 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.044819 |
| B2M | beta-2-microglobulin | -0.0432164 |
| GOLGA4 | golgin A4 | -0.0429695 |
| RPS3 | ribosomal protein S3 | -0.0415196 |
| RPS8 | ribosomal protein S8 | -0.0403454 |
| RPL19 | ribosomal protein L19 | -0.0384953 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0383737 |
| LDHA | lactate dehydrogenase A | -0.0383544 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0378874 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0370542 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0369603 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.036586 |
| PAX8 | paired box 8 | -0.0353849 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0351857 |
| TMSB4X | thymosin beta 4, X-linked | -0.0349236 |
| EZR | ezrin | -0.0347856 |
| VMP1 | vacuole membrane protein 1 | -0.034412 |
| TPM4 | tropomyosin 4 | -0.0336506 |
| RPL31 | ribosomal protein L31 | -0.0334521 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0333634 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0331477 |
| RPS12 | ribosomal protein S12 | -0.0331139 |
| ITGB8 | integrin, beta 8 | -0.0318471 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0312631 |
| YBX1 | Y box binding protein 1 | -0.0308136 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0306904 |
| RPS5 | ribosomal protein S5 | -0.0298766 |
| CALR | calreticulin | -0.0295766 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0295599 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0295219 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0289167 |
| SEPTIN7 | septin 7 | -0.028707 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0285233 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0281637 |
| RPL26 | ribosomal protein L26 | -0.0281011 |
| BPTF | bromodomain PHD finger transcription factor | -0.027937 |
| JMJD1C | jumonji domain containing 1C | -0.0277738 |
| TPM3 | tropomyosin 3 | -0.0271793 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0270254 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0268134 |
| NF1 | neurofibromin 1 | -0.0267579 |
| HDLBP | high density lipoprotein binding protein | -0.0266617 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0264616 |
| MYEOV | myeloma overexpressed | -0.0263735 |
| EPCAM | epithelial cell adhesion molecule | -0.0263382 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.026281 |
| DIAPH1 | diaphanous-related formin 1 | -0.0261748 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.026084 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0259582 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0256802 |
| PKM | pyruvate kinase, muscle | -0.0254758 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0254679 |
| MACROD2 | MACRO domain containing 2 | -0.0253264 |
| ANLN | anillin, actin binding protein | -0.0252777 |
| SQSTM1 | sequestosome 1 | -0.0250728 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0249634 |
| RPL12 | ribosomal protein L12 | -0.0243176 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0242664 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0240423 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0237384 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0235994 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0234592 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0234384 |
| RPL32 | ribosomal protein L32 | -0.023111 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0230641 |
| IPO7 | importin 7 | -0.0229836 |
| SETD2 | SET domain containing 2 | -0.0229168 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0229054 |
| KIAA1958 | KIAA1958 | -0.0227211 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0225994 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0225878 |
| RACK1 | receptor for activated C kinase 1 | -0.0223539 |
| RLF | rearranged L-myc fusion | -0.0222642 |
| MAP4 | microtubule-associated protein 4 | -0.0222598 |
| CD2AP | CD2-associated protein | -0.0221403 |
