| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glycyrrhizic acid_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.167871 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.126949 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.110983 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.109414 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0801881 |
| FLNA | filamin A, alpha | 0.0786303 |
| PKM | pyruvate kinase, muscle | 0.0625019 |
| LDHA | lactate dehydrogenase A | 0.0587343 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0558394 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.054529 |
| PGK1 | phosphoglycerate kinase 1 | 0.0490865 |
| ACTG1 | actin gamma 1 | 0.0476162 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0448682 |
| CCNL1 | cyclin L1 | 0.0442198 |
| NAV2 | neuron navigator 2 | 0.0438538 |
| IGF2 | insulin-like growth factor 2 | 0.0433594 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0429599 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0429552 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0421889 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0413638 |
| RPL9 | ribosomal protein L9 | 0.0407701 |
| HMGA1 | high mobility group AT-hook 1 | 0.0404336 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0399801 |
| RRM2 | ribonucleotide reductase M2 | 0.0396787 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0396195 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0388259 |
| FOSL1 | FOS-like antigen 1 | 0.0386129 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0374441 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0368005 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0356061 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0352121 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.034417 |
| FLNB | filamin B, beta | 0.0336695 |
| EGR1 | early growth response 1 | 0.033185 |
| COL7A1 | collagen, type VII, alpha 1 | 0.032007 |
| HJURP | Holliday junction recognition protein | 0.0311026 |
| PRELID2 | PRELI domain containing 2 | 0.0308491 |
| GANAB | glucosidase, alpha; neutral AB | 0.0303824 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0294936 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0294815 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0291583 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0286845 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0282802 |
| L1CAM | L1 cell adhesion molecule | 0.027929 |
| RPS19 | ribosomal protein S19 | 0.0275101 |
| USP22 | ubiquitin specific peptidase 22 | 0.027435 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0273222 |
| MRC2 | mannose receptor, C type 2 | 0.0269147 |
| MSN | moesin | 0.0269139 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0268869 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.02684 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0267153 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0258125 |
| AGRN | agrin | 0.0257232 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0256068 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0253454 |
| NUP58 | nucleoporin 58 | 0.0249993 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0248153 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0242763 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0242504 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0242423 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0240176 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0238866 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0234875 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.023146 |
| SP3 | Sp3 transcription factor | 0.0228776 |
| MCL1 | myeloid cell leukemia 1 | 0.0226352 |
| NDRG1 | N-myc downstream regulated 1 | 0.022597 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0223264 |
| G0S2 | G0/G1 switch 2 | 0.0216707 |
| RAI1 | retinoic acid induced 1 | 0.0214384 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0213781 |
| ANXA5 | annexin A5 | 0.0211721 |
| PODXL | podocalyxin-like | 0.0210811 |
| VASP | vasodilator-stimulated phosphoprotein | 0.021073 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0209891 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0208114 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.02013 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0200742 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0198423 |
| NKTR | natural killer cell triggering receptor | 0.0197164 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0196733 |
| PLEC | plectin | 0.019586 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0194578 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0193389 |
| PFN1 | profilin 1 | 0.0188841 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0188371 |
| RPS21 | ribosomal protein S21 | 0.0187757 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0187573 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0187134 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0185551 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0182279 |
| VEGFA | vascular endothelial growth factor A | 0.018075 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0178248 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0177786 |
| CAPRIN2 | caprin family member 2 | 0.0177727 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0176878 |
| LOXL2 | lysyl oxidase-like 2 | 0.0176698 |
| CEP95 | centrosomal protein 95kDa | 0.0176149 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0174629 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.373772 |
| TMSB10 | thymosin beta 10 | -0.213202 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.139492 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.131932 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.129887 |
| FN1 | fibronectin 1 | -0.12976 |
| PTMA | prothymosin, alpha | -0.117445 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0944803 |
| FTL | ferritin, light polypeptide | -0.0917583 |
| CANX | calnexin | -0.0851655 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0838819 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.083849 |
| IER3 | immediate early response 3 | -0.0792541 |
| ASPH | aspartate beta-hydroxylase | -0.0724507 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0713946 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0706874 |
| AHNAK | AHNAK nucleoprotein | -0.0694363 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.067634 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.063141 |
| RLF | rearranged L-myc fusion | -0.0578831 |
| ANXA2 | annexin A2 | -0.052717 |
| RAI14 | retinoic acid induced 14 | -0.0517331 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0515942 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0506638 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0493518 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0476283 |
| HMGA2 | high mobility group AT-hook 2 | -0.0468628 |
| HDLBP | high density lipoprotein binding protein | -0.0466357 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.044015 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0433562 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0427976 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.040284 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0368186 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0366585 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.036247 |
| YBX1 | Y box binding protein 1 | -0.0351255 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0347404 |
| RNF24 | ring finger protein 24 | -0.0345519 |
| GOLGB1 | golgin B1 | -0.0343218 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0332574 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0330282 |
| RPLP1 | ribosomal protein, large, P1 | -0.0330231 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0330221 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0327116 |
| CALU | calumenin | -0.0323917 |
| RPL12 | ribosomal protein L12 | -0.0321134 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0319127 |
| RPS24 | ribosomal protein S24 | -0.0316337 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0316058 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0314309 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.031272 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0312022 |
| RPL31 | ribosomal protein L31 | -0.0302245 |
| JUN | jun proto-oncogene | -0.0297722 |
| MAP4 | microtubule-associated protein 4 | -0.0295651 |
| FBXO11 | F-box protein 11 | -0.0295132 |
| VCL | vinculin | -0.0292132 |
| S100A10 | S100 calcium binding protein A10 | -0.0291106 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.028729 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.028714 |
| RYBP | RING1 and YY1 binding protein | -0.0286914 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0285819 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0283568 |
| QKI | QKI, KH domain containing, RNA binding | -0.0282083 |
| RPS8 | ribosomal protein S8 | -0.027914 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0276419 |
| RRBP1 | ribosome binding protein 1 | -0.0274488 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0271558 |
| LMNA | lamin A/C | -0.0267418 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0264924 |
| FAM162A | family with sequence similarity 162, member A | -0.0263663 |
| RPL32 | ribosomal protein L32 | -0.0260925 |
| KPNB1 | karyopherin (importin) beta 1 | -0.025772 |
| MAP1B | microtubule-associated protein 1B | -0.0253729 |
| CDH13 | cadherin 13 | -0.0252923 |
| UBC | ubiquitin C | -0.0250834 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0250591 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0250568 |
| TXNRD1 | thioredoxin reductase 1 | -0.0250307 |
| CCND1 | cyclin D1 | -0.0249485 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0246226 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0237221 |
| SEC24A | SEC24 family member A | -0.0237046 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.023573 |
| TPM4 | tropomyosin 4 | -0.0231952 |
| RPS3 | ribosomal protein S3 | -0.0230504 |
| VMP1 | vacuole membrane protein 1 | -0.0229729 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.022947 |
| CCDC47 | coiled-coil domain containing 47 | -0.0229029 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0228776 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0226951 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0223777 |
| NOP58 | NOP58 ribonucleoprotein | -0.0222734 |
| GLG1 | golgi glycoprotein 1 | -0.0221148 |
| TMEM263 | transmembrane protein 263 | -0.0219953 |
| RPS27A | ribosomal protein S27a | -0.0219693 |
| TAOK1 | TAO kinase 1 | -0.0218371 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.02123 |
| EMP1 | epithelial membrane protein 1 | -0.0211915 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0211818 |
