| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Glycyrrhizic acid_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.151038 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0963374 |
| ATP13A3 | ATPase type 13A3 | 0.0850355 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0776264 |
| MT2A | metallothionein 2A | 0.0705698 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0663175 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0626962 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0603558 |
| ACTG1 | actin gamma 1 | 0.0595819 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0573666 |
| CADM1 | cell adhesion molecule 1 | 0.0501562 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0495884 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0474871 |
| FN1 | fibronectin 1 | 0.0458398 |
| LOXL2 | lysyl oxidase-like 2 | 0.0447989 |
| RPS6 | ribosomal protein S6 | 0.0433539 |
| CCNL1 | cyclin L1 | 0.0412432 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0383385 |
| RASA2 | RAS p21 protein activator 2 | 0.0352081 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0349298 |
| FLNA | filamin A, alpha | 0.0347331 |
| RPL35A | ribosomal protein L35a | 0.0327529 |
| LOX | lysyl oxidase | 0.0317936 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0306353 |
| RPL11 | ribosomal protein L11 | 0.0306213 |
| NAV2 | neuron navigator 2 | 0.0305429 |
| RPS19 | ribosomal protein S19 | 0.0298547 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0293957 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.029111 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0282198 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0270224 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.026395 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0256351 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0247478 |
| GANAB | glucosidase, alpha; neutral AB | 0.0247177 |
| RPL9 | ribosomal protein L9 | 0.0245948 |
| PGK1 | phosphoglycerate kinase 1 | 0.0245767 |
| SMAD3 | SMAD family member 3 | 0.0245593 |
| MTSS1 | metastasis suppressor 1 | 0.0243804 |
| RPS21 | ribosomal protein S21 | 0.024244 |
| TSC22D2 | TSC22 domain family, member 2 | 0.024135 |
| TMEM165 | transmembrane protein 165 | 0.0239099 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0233697 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0230245 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0228731 |
| PTK2 | protein tyrosine kinase 2 | 0.0228102 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0223619 |
| CAVIN1 | caveolae associated protein 1 | 0.0221196 |
| EGFR | epidermal growth factor receptor | 0.0220799 |
| HMGA1 | high mobility group AT-hook 1 | 0.0219252 |
| ZNF292 | zinc finger protein 292 | 0.0217153 |
| RPS13 | ribosomal protein S13 | 0.0216138 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0209304 |
| ADM | adrenomedullin | 0.0207831 |
| RPL36 | ribosomal protein L36 | 0.0207647 |
| RPL37 | ribosomal protein L37 | 0.0206804 |
| RPL27 | ribosomal protein L27 | 0.020349 |
| RPS2 | ribosomal protein S2 | 0.0200787 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0198729 |
| TRAM1 | translocation associated membrane protein 1 | 0.019718 |
| GNAS | GNAS complex locus | 0.0194979 |
| WASF2 | WAS protein family, member 2 | 0.0192401 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0191566 |
| FOXJ3 | forkhead box J3 | 0.0189931 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0189724 |
| PKM | pyruvate kinase, muscle | 0.0188858 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0188373 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0187262 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0184269 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0180398 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0179941 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0179463 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0176424 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0176027 |
| PRELID2 | PRELI domain containing 2 | 0.0175005 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0173758 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.017315 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0170938 |
| RPL13A | ribosomal protein L13a | 0.0170102 |
| HMGA2 | high mobility group AT-hook 2 | 0.0169513 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0168675 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.016826 |
| ANXA5 | annexin A5 | 0.016634 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0166292 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0165389 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0164701 |
| RYK | receptor-like tyrosine kinase | 0.0163492 |
| CCDC88A | coiled-coil domain containing 88A | 0.0161976 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0161836 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0161358 |
| POLDIP3 | polymerase (DNA-directed), delta interacting protein 3 | 0.0160248 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0160083 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0159797 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0159049 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0158942 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0158773 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0157458 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0156587 |
| SFTPA2 | surfactant protein A2 | 0.0156468 |
| FOSL1 | FOS-like antigen 1 | 0.0156456 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.175085 |
| TMSB10 | thymosin beta 10 | -0.105322 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.104875 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0990774 |
| UBC | ubiquitin C | -0.0848281 |
| COL1A1 | collagen, type I, alpha 1 | -0.0775235 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0724462 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0655089 |
| PTMA | prothymosin, alpha | -0.0578586 |
| NDRG1 | N-myc downstream regulated 1 | -0.0557223 |
| ENO1 | enolase 1, (alpha) | -0.0547335 |
| FTL | ferritin, light polypeptide | -0.0504785 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0498426 |
| AHNAK | AHNAK nucleoprotein | -0.0490764 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0478807 |
| CD44 | CD44 molecule (Indian blood group) | -0.0441002 |
| CANX | calnexin | -0.0440417 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0382685 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.037954 |
| FBN1 | fibrillin 1 | -0.0364054 |
| TPM4 | tropomyosin 4 | -0.0360465 |
| COL1A2 | collagen, type I, alpha 2 | -0.0349992 |
| ASPH | aspartate beta-hydroxylase | -0.0323891 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0315149 |
| IER3 | immediate early response 3 | -0.0302683 |
| CALU | calumenin | -0.0296049 |
| YBX1 | Y box binding protein 1 | -0.0289492 |
| COL3A1 | collagen, type III, alpha 1 | -0.0282775 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0279235 |
| VCAN | versican | -0.0271566 |
| JUN | jun proto-oncogene | -0.0267912 |
| CALR | calreticulin | -0.0263518 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0262423 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0260654 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0258373 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0251134 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0249604 |
| INHBA | inhibin, beta A | -0.0248273 |
| CLIC4 | chloride intracellular channel 4 | -0.0247724 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0246228 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0244431 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.02422 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0239876 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0229503 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0229355 |
| MAP1B | microtubule-associated protein 1B | -0.0226969 |
| SERINC3 | serine incorporator 3 | -0.0218454 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0215371 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0212697 |
| RIGI | RNA sensor RIG-I | -0.0211116 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0208405 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0207561 |
| RRBP1 | ribosome binding protein 1 | -0.0203982 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0202263 |
| RPS27A | ribosomal protein S27a | -0.019239 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.019173 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.019117 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0188802 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0186227 |
| SP100 | SP100 nuclear antigen | -0.0181711 |
| RPS3 | ribosomal protein S3 | -0.0181075 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0172813 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0172148 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0171889 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.017075 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0167765 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0165697 |
| S100A10 | S100 calcium binding protein A10 | -0.0164718 |
| VMP1 | vacuole membrane protein 1 | -0.0161895 |
| GOLGB1 | golgin B1 | -0.016135 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0158231 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0157906 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0156658 |
| MAP4 | microtubule-associated protein 4 | -0.0155865 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.015503 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0154111 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0151033 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0149273 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0148026 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0146806 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa | -0.0143636 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0139217 |
| RPS5 | ribosomal protein S5 | -0.0138924 |
| TPM3 | tropomyosin 3 | -0.013887 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0137282 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0137194 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0136444 |
| TOP1 | topoisomerase (DNA) I | -0.013574 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0132204 |
| VCL | vinculin | -0.0130829 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0129301 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0129155 |
| ARF4 | ADP-ribosylation factor 4 | -0.0127787 |
| KPNB1 | karyopherin (importin) beta 1 | -0.012741 |
| ATXN1 | ataxin 1 | -0.0127369 |
| HDAC9 | histone deacetylase 9 | -0.0127039 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0126966 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0126624 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0125422 |
| RPS12 | ribosomal protein S12 | -0.0125075 |