| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glycyrrhizic acid_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.16615 |
| SLC38A2 | solute carrier family 38, member 2 | 0.133852 |
| TF | transferrin | 0.108242 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.102359 |
| FN1 | fibronectin 1 | 0.102236 |
| APOB | apolipoprotein B | 0.0945616 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0921681 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.082508 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0808787 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0763578 |
| SDC4 | syndecan 4 | 0.0734114 |
| GPC3 | glypican 3 | 0.0720158 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0715645 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.069795 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.065112 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0620195 |
| RPL23 | ribosomal protein L23 | 0.0599466 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0593933 |
| RPL9 | ribosomal protein L9 | 0.0585883 |
| RPS6 | ribosomal protein S6 | 0.0566838 |
| RPL11 | ribosomal protein L11 | 0.0539672 |
| CCNL1 | cyclin L1 | 0.0509305 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0496988 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0495343 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0494388 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0493361 |
| FAT1 | FAT atypical cadherin 1 | 0.0487912 |
| RPS19 | ribosomal protein S19 | 0.0485809 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0483927 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0482679 |
| MSI2 | musashi RNA-binding protein 2 | 0.0468558 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0468001 |
| RPS29 | ribosomal protein S29 | 0.0465429 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0461876 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0460528 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0457051 |
| A2M | alpha-2-macroglobulin | 0.0444722 |
| RPS11 | ribosomal protein S11 | 0.0431357 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0426003 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0422702 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0418762 |
| RPL34 | ribosomal protein L34 | 0.0412271 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0411884 |
| RPL13A | ribosomal protein L13a | 0.0410923 |
| RPS21 | ribosomal protein S21 | 0.0410086 |
| CPE | carboxypeptidase E | 0.0409673 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0406667 |
| PARD3 | par-3 family cell polarity regulator | 0.0403471 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0397649 |
| RPL37 | ribosomal protein L37 | 0.0396635 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0392632 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0386005 |
| AFDN | afadin, adherens junction formation factor | 0.0384666 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0380132 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0375745 |
| RPL12 | ribosomal protein L12 | 0.0364864 |
| RPS23 | ribosomal protein S23 | 0.0363129 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0361949 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0352798 |
| MTSS1 | metastasis suppressor 1 | 0.0344597 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.034321 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0341715 |
| PUM2 | pumilio RNA-binding family member 2 | 0.033879 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0337585 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.033604 |
| DTNA | dystrobrevin, alpha | 0.0335626 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0333435 |
| C3 | complement component 3 | 0.0332502 |
| RPS2 | ribosomal protein S2 | 0.0330402 |
| RPL27 | ribosomal protein L27 | 0.0325605 |
| ATXN1 | ataxin 1 | 0.0323308 |
| RPS13 | ribosomal protein S13 | 0.032328 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0323139 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0321736 |
| RPL26 | ribosomal protein L26 | 0.0320066 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0318728 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0306537 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0301318 |
| AHR | aryl hydrocarbon receptor | 0.0299996 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0299887 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0293424 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0291955 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0289485 |
| SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 | 0.0284516 |
| FUS | FUS RNA binding protein | 0.0284351 |
| RPL4 | ribosomal protein L4 | 0.0284247 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0284013 |
| TMEM123 | transmembrane protein 123 | 0.0282688 |
| ATP13A3 | ATPase type 13A3 | 0.0277395 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0276306 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0275767 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0274657 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0273364 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0271256 |
| SETD5 | SET domain containing 5 | 0.0269702 |
| TOP1 | topoisomerase (DNA) I | 0.026511 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0264734 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0263799 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0262387 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0261916 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.309864 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.163829 |
| IGF2 | insulin-like growth factor 2 | -0.153317 |
| FTL | ferritin, light polypeptide | -0.0957972 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0817763 |
| TMSB10 | thymosin beta 10 | -0.0704924 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0700365 |
| PLIN2 | perilipin 2 | -0.0454784 |
| NDRG1 | N-myc downstream regulated 1 | -0.0361511 |
| APOE | apolipoprotein E | -0.0329248 |
| RPL31 | ribosomal protein L31 | -0.0313539 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0301007 |
| CST3 | cystatin C | -0.0297942 |
| VCL | vinculin | -0.0267703 |
| FOXP1 | forkhead box P1 | -0.0253892 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0253046 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0252816 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0252766 |
| RPS12 | ribosomal protein S12 | -0.0248322 |
| BBX | bobby sox homolog (Drosophila) | -0.0238356 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0234262 |
| LYZ | lysozyme | -0.0229385 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0220505 |
| BRD4 | bromodomain containing 4 | -0.0204228 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0200261 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0195537 |
| SMYD3 | SET and MYND domain containing 3 | -0.0195481 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0194807 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0189876 |
| STC2 | stanniocalcin 2 | -0.0186659 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0186175 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.01828 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0180508 |
| BPIFB2 | BPI fold containing family B, member 2 | -0.0180287 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.017953 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0172859 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0172275 |
| RYBP | RING1 and YY1 binding protein | -0.0172177 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0172019 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0170175 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0169601 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0168382 |
| RIGI | RNA sensor RIG-I | -0.0167679 |
| CDK13 | cyclin-dependent kinase 13 | -0.0167406 |
| RPS5 | ribosomal protein S5 | -0.0166511 |
| GLRX | glutaredoxin (thioltransferase) | -0.016523 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0164708 |
| ECE1 | endothelin converting enzyme 1 | -0.0164209 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0162191 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0161715 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0158625 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0158392 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0156556 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0155459 |
| MYO1E | myosin IE | -0.0155126 |
| CEP350 | centrosomal protein 350kDa | -0.0153897 |
| PHF21A | PHD finger protein 21A | -0.0152165 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0148265 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0147328 |
| MT1X | metallothionein 1X | -0.0145809 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0145226 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0144656 |
| MT1G | metallothionein 1G | -0.0143112 |
| ITGA6 | integrin, alpha 6 | -0.0141705 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.014079 |
| FAM107B | family with sequence similarity 107, member B | -0.0139446 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0139259 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0136977 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0136225 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0135395 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0135283 |
| EHBP1 | EH domain binding protein 1 | -0.0135017 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.013455 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0133228 |
| YIPF5 | Yip1 domain family, member 5 | -0.0132838 |
| TPM1 | tropomyosin 1 (alpha) | -0.0132723 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0131661 |
| HNMT | histamine N-methyltransferase | -0.01316 |
| CCNC | cyclin C | -0.0130966 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0130811 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -0.0130647 |
| GPHN | gephyrin | -0.0130364 |
| CUX1 | cut-like homeobox 1 | -0.0130251 |
| SUMF1 | sulfatase modifying factor 1 | -0.0130041 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0129576 |
| RAD51B | RAD51 paralog B | -0.0129288 |
| POTEF | POTE ankyrin domain family, member F | -0.012808 |
| UBE4A | ubiquitination factor E4A | -0.0126801 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -0.0126163 |
| WDR70 | WD repeat domain 70 | -0.0125912 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -0.0124943 |
| REEP3 | receptor accessory protein 3 | -0.0123851 |
| IP6K1 | inositol hexakisphosphate kinase 1 | -0.0123775 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0123428 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0123079 |
| TMEM87A | transmembrane protein 87A | -0.0121558 |
| COMMD10 | COMM domain containing 10 | -0.0120695 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0120112 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0119394 |
| BRD7 | bromodomain containing 7 | -0.0119176 |
