| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glycyrrhizic acid_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.210966 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.104183 |
| ASPH | aspartate beta-hydroxylase | 0.0943054 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0743581 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0714807 |
| PKM | pyruvate kinase, muscle | 0.069405 |
| FNDC3B | fibronectin type III domain containing 3B | 0.057484 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0469324 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0459809 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0445464 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.043295 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0421576 |
| LDHA | lactate dehydrogenase A | 0.0398379 |
| NPAS2 | neuronal PAS domain protein 2 | 0.037609 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0364291 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.035591 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0352185 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0346446 |
| KRT7 | keratin 7, type II | 0.0340241 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0334769 |
| ACTG1 | actin gamma 1 | 0.031553 |
| SMAD3 | SMAD family member 3 | 0.0315044 |
| LAMC2 | laminin, gamma 2 | 0.0313974 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0307951 |
| CCNL1 | cyclin L1 | 0.0306658 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0297123 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0291823 |
| CAV2 | caveolin 2 | 0.0288337 |
| MXD1 | MAX dimerization protein 1 | 0.0280678 |
| FLNB | filamin B, beta | 0.0279196 |
| PGK1 | phosphoglycerate kinase 1 | 0.0277164 |
| SCEL | sciellin | 0.027194 |
| PLEC | plectin | 0.0270297 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0269281 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0267515 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0265466 |
| B2M | beta-2-microglobulin | 0.0263479 |
| FAM13A | family with sequence similarity 13, member A | 0.0262159 |
| RNF213 | ring finger protein 213 | 0.0261503 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0258956 |
| KRT18 | keratin 18, type I | 0.0257225 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0249701 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0249327 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0242307 |
| ARRDC3 | arrestin domain containing 3 | 0.0236442 |
| NDRG1 | N-myc downstream regulated 1 | 0.0236217 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0233967 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0229578 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0229559 |
| EFNA5 | ephrin-A5 | 0.0222208 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.021846 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0215599 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0211016 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0210899 |
| LAMB3 | laminin, beta 3 | 0.020688 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0206863 |
| APP | amyloid beta (A4) precursor protein | 0.0201314 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0201294 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.019982 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0199744 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0197252 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0196001 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0189234 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.018913 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0183671 |
| PARD3 | par-3 family cell polarity regulator | 0.0183214 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0182628 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0180458 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0180123 |
| KRT19 | keratin 19, type I | 0.0178324 |
| ENO1 | enolase 1, (alpha) | 0.0177338 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0175437 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0174338 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0171179 |
| MCL1 | myeloid cell leukemia 1 | 0.016989 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0169356 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.0169049 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0168542 |
| MSN | moesin | 0.0168071 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0167527 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0166534 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0166493 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0165834 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0164507 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0163846 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0162024 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0157565 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0156667 |
| SLMAP | sarcolemma associated protein | 0.0155393 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0155299 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0153076 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0152446 |
| NUP58 | nucleoporin 58 | 0.0151995 |
| SEC61G | Sec61 gamma subunit | 0.0150433 |
| SUMF1 | sulfatase modifying factor 1 | 0.0150323 |
| CPE | carboxypeptidase E | 0.0149003 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0148699 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0148018 |
| SP3 | Sp3 transcription factor | 0.014781 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0147483 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0839315 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.070915 |
| FTL | ferritin, light polypeptide | -0.0674894 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0647719 |
| PTMA | prothymosin, alpha | -0.0497767 |
| CANX | calnexin | -0.0489599 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0426776 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0413548 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0392517 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0392441 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.037884 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0347624 |
| TES | testin LIM domain protein | -0.0346111 |
| SPAG9 | sperm associated antigen 9 | -0.0345556 |
| GOLGB1 | golgin B1 | -0.0333005 |
| NABP1 | nucleic acid binding protein 1 | -0.0321181 |
| TMSB10 | thymosin beta 10 | -0.0319751 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0292792 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0292083 |
| RPS24 | ribosomal protein S24 | -0.0277818 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.026687 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0265749 |
| MT2A | metallothionein 2A | -0.0264101 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0256828 |
| RPLP0 | ribosomal protein, large, P0 | -0.0253382 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0249966 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0241776 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0241557 |
| INTS6 | integrator complex subunit 6 | -0.0238504 |
| OGA | O-GlcNAcase | -0.0238188 |
| RPS8 | ribosomal protein S8 | -0.0235478 |
| JMJD1C | jumonji domain containing 1C | -0.0235252 |
| LAMA4 | laminin, alpha 4 | -0.0235186 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0234785 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0232599 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0229213 |
| RPLP1 | ribosomal protein, large, P1 | -0.0227266 |
| IER3 | immediate early response 3 | -0.0222257 |
| MORF4L2 | mortality factor 4 like 2 | -0.0219967 |
| RPL31 | ribosomal protein L31 | -0.0217396 |
| TXNRD1 | thioredoxin reductase 1 | -0.0216168 |
| HBP1 | HMG-box transcription factor 1 | -0.021016 |
| RPL12 | ribosomal protein L12 | -0.0208 |
| GM2A | GM2 ganglioside activator | -0.0206629 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0205296 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0203861 |
| HDLBP | high density lipoprotein binding protein | -0.0199245 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.019879 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0195315 |
| TBC1D22A | TBC1 domain family, member 22A | -0.01943 |
| RPS3 | ribosomal protein S3 | -0.0189067 |
| H1-0 | H1.0 linker histone | -0.0188768 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0188081 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0182866 |
| SYAP1 | synapse associated protein 1 | -0.0178052 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0175627 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0174241 |
| VMP1 | vacuole membrane protein 1 | -0.0171233 |
| RPS27A | ribosomal protein S27a | -0.0171097 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0170737 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0165616 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.01638 |
| MYO6 | myosin VI | -0.0162604 |
| RLF | rearranged L-myc fusion | -0.0161783 |
| RPL19 | ribosomal protein L19 | -0.0160752 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0160083 |
| RPS25 | ribosomal protein S25 | -0.016007 |
| TAOK1 | TAO kinase 1 | -0.0158333 |
| CCNI | cyclin I | -0.0157739 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0157597 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0156385 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0154361 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0153218 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0151634 |
| ECD | ecdysoneless homolog (Drosophila) | -0.0151269 |
| IRF1 | interferon regulatory factor 1 | -0.0151225 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0151062 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.014742 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.01473 |
| RPS12 | ribosomal protein S12 | -0.0145536 |
| TMEM87A | transmembrane protein 87A | -0.0144431 |
| ENSA | endosulfine alpha | -0.0144337 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0143767 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0142827 |
| RPS6 | ribosomal protein S6 | -0.0141067 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0140614 |
| NF1 | neurofibromin 1 | -0.0139788 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0137669 |
| MKI67 | marker of proliferation Ki-67 | -0.0136831 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0136526 |
| RPS23 | ribosomal protein S23 | -0.0135472 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0134688 |
| FAM110C | family with sequence similarity 110, member C | -0.0133732 |
| BPTF | bromodomain PHD finger transcription factor | -0.013338 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0131135 |
| EZR | ezrin | -0.0130475 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0130365 |
| SIK3 | SIK family kinase 3 | -0.0130317 |
| CCNH | cyclin H | -0.0128753 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.0127143 |
