| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Glycyrrhizic acid_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0954759 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0719991 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0653392 |
| RPL4 | ribosomal protein L4 | 0.0358383 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0337137 |
| YBX3 | Y box binding protein 3 | 0.0333947 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0303329 |
| USP3 | ubiquitin specific peptidase 3 | 0.0294241 |
| RRM2 | ribonucleotide reductase M2 | 0.0293274 |
| RTN4 | reticulon 4 | 0.0281501 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0281422 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0276877 |
| CCNL1 | cyclin L1 | 0.0270299 |
| NUP58 | nucleoporin 58 | 0.026024 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0260155 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0247605 |
| WDR43 | WD repeat domain 43 | 0.0244919 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0242892 |
| APP | amyloid beta (A4) precursor protein | 0.023252 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.022856 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.022654 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0226217 |
| ZNF292 | zinc finger protein 292 | 0.0225221 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0223414 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0219698 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0218936 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0205115 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.020437 |
| FAM168A | family with sequence similarity 168, member A | 0.0198006 |
| JAK1 | Janus kinase 1 | 0.0197609 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.019649 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0194507 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0189301 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0180194 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0176233 |
| NCKAP1 | NCK-associated protein 1 | 0.017396 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.017329 |
| PKM | pyruvate kinase, muscle | 0.0172191 |
| RBM33 | RNA binding motif protein 33 | 0.0170725 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0168887 |
| RBM39 | RNA binding motif protein 39 | 0.0163994 |
| ANXA5 | annexin A5 | 0.0162317 |
| FLNA | filamin A, alpha | 0.0161672 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.01602 |
| THBS1 | thrombospondin 1 | 0.0157906 |
| MKI67 | marker of proliferation Ki-67 | 0.0155723 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0154275 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0154044 |
| SMAD3 | SMAD family member 3 | 0.0152125 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0151984 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0150245 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0150215 |
| PDS5A | PDS5 cohesin associated factor A | 0.0149557 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0149267 |
| ECT2 | epithelial cell transforming 2 | 0.0148174 |
| SPAG9 | sperm associated antigen 9 | 0.0147972 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0146728 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0144249 |
| CHN1 | chimerin 1 | 0.014404 |
| OLA1 | Obg-like ATPase 1 | 0.0143729 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0142635 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0142105 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0141723 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0141424 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0140286 |
| TMEM123 | transmembrane protein 123 | 0.0140008 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0139526 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0139113 |
| SP3 | Sp3 transcription factor | 0.0138428 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0136347 |
| MATR3 | matrin 3 | 0.0135916 |
| MTMR3 | myotubularin related protein 3 | 0.0132119 |
| CPNE8 | copine VIII | 0.0132013 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0131999 |
| PTK2 | protein tyrosine kinase 2 | 0.0131846 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0131211 |
| NUP153 | nucleoporin 153kDa | 0.013076 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0129885 |
| RPL13A | ribosomal protein L13a | 0.0128761 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0128315 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0127828 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0127608 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0126479 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0125318 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0125256 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0125011 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0124855 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.012444 |
| WBP11 | WW domain binding protein 11 | 0.0124368 |
| UCK2 | uridine-cytidine kinase 2 | 0.0124162 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.0123987 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0123628 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0123154 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.012271 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 0.0122642 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0121969 |
| CBFB | core-binding factor, beta subunit | 0.0121785 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0121353 |
| RPS21 | ribosomal protein S21 | 0.0120775 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.012062 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.137202 |
| FTL | ferritin, light polypeptide | -0.113191 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0846415 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0835391 |
| VIM | vimentin | -0.0722431 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0469027 |
| MT2A | metallothionein 2A | -0.0435953 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0383742 |
| DOCK4 | dedicator of cytokinesis 4 | -0.035701 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0342044 |
| EGR1 | early growth response 1 | -0.0315783 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0314845 |
| IGF2 | insulin-like growth factor 2 | -0.0307865 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0259748 |
| SVIL | supervillin | -0.0241153 |
| GRAMD1B | GRAM domain containing 1B | -0.0240608 |
| IER3 | immediate early response 3 | -0.0231277 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0223124 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0220333 |
| RPL31 | ribosomal protein L31 | -0.0218172 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0213237 |
| S100A6 | S100 calcium binding protein A6 | -0.0211427 |
| TPM4 | tropomyosin 4 | -0.0211296 |
| POTEF | POTE ankyrin domain family, member F | -0.0209656 |
| TXNRD1 | thioredoxin reductase 1 | -0.0206235 |
| RPS17 | ribosomal protein S17 | -0.0199589 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0193894 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0193812 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0188827 |
| CMIP | c-Maf inducing protein | -0.0187155 |
| OSMR | oncostatin M receptor | -0.0184046 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0175364 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0172121 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0169565 |
| BICC1 | BicC family RNA binding protein 1 | -0.0167106 |
| PYGL | phosphorylase, glycogen, liver | -0.0164361 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0163042 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0163002 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0159785 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0156539 |
| HLA-B | major histocompatibility complex, class I, B | -0.0154347 |
| RPL19 | ribosomal protein L19 | -0.0152616 |
| HDAC9 | histone deacetylase 9 | -0.0150105 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.014828 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0148061 |
| NEBL | nebulette | -0.0147996 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0147838 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0144599 |
| S100A10 | S100 calcium binding protein A10 | -0.0140048 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0138834 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0137436 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.013723 |
| VMP1 | vacuole membrane protein 1 | -0.0135156 |
| EHBP1 | EH domain binding protein 1 | -0.0134795 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0131585 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0131484 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0130241 |
| KYNU | kynureninase | -0.0128392 |
| EGFR | epidermal growth factor receptor | -0.0126456 |
| NTN4 | netrin 4 | -0.0125612 |
| COPA | coatomer protein complex, subunit alpha | -0.0124567 |
| PLS3 | plastin 3 | -0.0124107 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0123254 |
| CUX1 | cut-like homeobox 1 | -0.0122588 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0121647 |
| RPL36AL | ribosomal protein L36a-like | -0.0120847 |
| PCNX4 | pecanex 4 | -0.0119693 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0118885 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0118227 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0113202 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0111733 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0111709 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0111206 |
| FGB | fibrinogen beta chain | -0.0109225 |
| ASTN2 | astrotactin 2 | -0.0107793 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0107681 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0107611 |
| GLIS3 | GLIS family zinc finger 3 | -0.010695 |
| TMEM87A | transmembrane protein 87A | -0.0106829 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.010633 |
| RPL28 | ribosomal protein L28 | -0.0103967 |
| CALD1 | caldesmon 1 | -0.0102941 |
| MCL1 | myeloid cell leukemia 1 | -0.0102239 |
| RPS8 | ribosomal protein S8 | -0.0101009 |
| RPS3 | ribosomal protein S3 | -0.0100805 |
| CDK12 | cyclin-dependent kinase 12 | -0.010047 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0100327 |
| ARF4 | ADP-ribosylation factor 4 | -0.00996944 |
| RPS27A | ribosomal protein S27a | -0.00993454 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.00990613 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00989724 |
| RAB31 | RAB31, member RAS oncogene family | -0.00984809 |
| LAMC2 | laminin, gamma 2 | -0.0098004 |
| BRD2 | bromodomain containing 2 | -0.00975413 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.00973106 |
| JMJD1C | jumonji domain containing 1C | -0.00971851 |
| GLG1 | golgi glycoprotein 1 | -0.00965974 |
| RPS12 | ribosomal protein S12 | -0.00959162 |
| BPTF | bromodomain PHD finger transcription factor | -0.00951405 |
| NEGR1 | neuronal growth regulator 1 | -0.00944955 |