| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glycyrrhizic acid_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.273065 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.171802 |
| ACTG1 | actin gamma 1 | 0.135489 |
| HMGA1 | high mobility group AT-hook 1 | 0.109882 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0921703 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0862203 |
| LDHA | lactate dehydrogenase A | 0.0779827 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0753949 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0722244 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0711571 |
| CCNL1 | cyclin L1 | 0.069266 |
| POTEF | POTE ankyrin domain family, member F | 0.067633 |
| KRT7 | keratin 7, type II | 0.066039 |
| PKM | pyruvate kinase, muscle | 0.065653 |
| PGK1 | phosphoglycerate kinase 1 | 0.0623749 |
| FLNA | filamin A, alpha | 0.0613796 |
| PLAU | plasminogen activator, urokinase | 0.0544813 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0513799 |
| CALR | calreticulin | 0.0466363 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0461711 |
| RPL35A | ribosomal protein L35a | 0.0440525 |
| NAV2 | neuron navigator 2 | 0.043905 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0436054 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.042425 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0400775 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0390059 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0381199 |
| MXD1 | MAX dimerization protein 1 | 0.0377437 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0375169 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0371988 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0364754 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0361635 |
| NUP58 | nucleoporin 58 | 0.0349226 |
| RPL23 | ribosomal protein L23 | 0.0341247 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0332617 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0325125 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0323174 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0299604 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0296745 |
| RPL4 | ribosomal protein L4 | 0.0287742 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0282891 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0273181 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0271449 |
| ZNF292 | zinc finger protein 292 | 0.0267443 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0262061 |
| USP3 | ubiquitin specific peptidase 3 | 0.0253728 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0253097 |
| FLNB | filamin B, beta | 0.0246484 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0245557 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0245521 |
| PFN1 | profilin 1 | 0.0242491 |
| ZNF207 | zinc finger protein 207 | 0.0238404 |
| MSI2 | musashi RNA-binding protein 2 | 0.0238267 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0235259 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0234673 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.0234001 |
| TUBB | tubulin, beta class I | 0.0233975 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0231679 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0230173 |
| LDHB | lactate dehydrogenase B | 0.0227887 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0224524 |
| KRT8 | keratin 8, type II | 0.0223946 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0223851 |
| CCND1 | cyclin D1 | 0.0220356 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.021611 |
| RPL9 | ribosomal protein L9 | 0.0215473 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0214525 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0208701 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0207768 |
| GANAB | glucosidase, alpha; neutral AB | 0.0205657 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0205354 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0205132 |
| DEK | DEK proto-oncogene | 0.020216 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0199494 |
| FLNC | filamin C, gamma | 0.0196168 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0193753 |
| RPL13A | ribosomal protein L13a | 0.0191831 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0191325 |
| ARF6 | ADP-ribosylation factor 6 | 0.0190443 |
| ACTN4 | actinin, alpha 4 | 0.0189388 |
| RAB21 | RAB21, member RAS oncogene family | 0.0186711 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0185808 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0185573 |
| TAGLN2 | transgelin 2 | 0.0184946 |
| NCKAP1 | NCK-associated protein 1 | 0.0184023 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0183953 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0182312 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0180593 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0180106 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0179504 |
| PRRC1 | proline-rich coiled-coil 1 | 0.017798 |
| CLIC1 | chloride intracellular channel 1 | 0.0173843 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.017304 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0171306 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0170915 |
| RPSA | ribosomal protein SA | 0.0170204 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0170156 |
| LONP1 | lon peptidase 1, mitochondrial | 0.0168135 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | 0.0167345 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0166166 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.215094 |
| FTL | ferritin, light polypeptide | -0.169896 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.133494 |
| PTMA | prothymosin, alpha | -0.116337 |
| NDRG1 | N-myc downstream regulated 1 | -0.0904237 |
| TMSB10 | thymosin beta 10 | -0.0819102 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0798983 |
| LAMC2 | laminin, gamma 2 | -0.0795962 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.078534 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0705252 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0684609 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0678269 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0653467 |
| LMO7 | LIM domain 7 | -0.0585809 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0576507 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0573948 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0559599 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0556491 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0544948 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0534082 |
| EPCAM | epithelial cell adhesion molecule | -0.0493849 |
| TMSB4X | thymosin beta 4, X-linked | -0.0489166 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0479826 |
| ASPH | aspartate beta-hydroxylase | -0.0472157 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0471463 |
| DSPP | dentin sialophosphoprotein | -0.0464149 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0457423 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0451206 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0437269 |
| GOLGA4 | golgin A4 | -0.0436273 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0431836 |
| RPS12 | ribosomal protein S12 | -0.0410493 |
| EFNA5 | ephrin-A5 | -0.0407341 |
| MYO6 | myosin VI | -0.0407176 |
| EZR | ezrin | -0.040657 |
| TMF1 | TATA element modulatory factor 1 | -0.0401542 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0400844 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.039386 |
| RPS3 | ribosomal protein S3 | -0.039368 |
| TPM3 | tropomyosin 3 | -0.0374513 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0362558 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.035568 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0351399 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0342019 |
| OGA | O-GlcNAcase | -0.0338654 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0336481 |
| DSG2 | desmoglein 2 | -0.0333946 |
| DTNA | dystrobrevin, alpha | -0.0333724 |
| S100A10 | S100 calcium binding protein A10 | -0.0331618 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0326228 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0322495 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0319985 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0319227 |
| TXNIP | thioredoxin interacting protein | -0.0319108 |
| ANO6 | anoctamin 6 | -0.0314515 |
| GOLGB1 | golgin B1 | -0.0303443 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0299815 |
| RPS17 | ribosomal protein S17 | -0.0299144 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0295747 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.029499 |
| UBC | ubiquitin C | -0.0294305 |
| MYO1E | myosin IE | -0.0294138 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0291774 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0290777 |
| ERBIN | erbb2 interacting protein | -0.0287898 |
| USP53 | ubiquitin specific peptidase 53 | -0.0286686 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0280023 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0277012 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0269936 |
| RPL26 | ribosomal protein L26 | -0.0269499 |
| AHNAK | AHNAK nucleoprotein | -0.0269425 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0268019 |
| CD2AP | CD2-associated protein | -0.0266414 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0263987 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.026327 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0262598 |
| RPS27A | ribosomal protein S27a | -0.0257304 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0256934 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0256296 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0252245 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0252109 |
| SNX6 | sorting nexin 6 | -0.0251533 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0250737 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.025052 |
| RPL5 | ribosomal protein L5 | -0.0248787 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0247462 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0246398 |
| CEP350 | centrosomal protein 350kDa | -0.0246059 |
| MX1 | MX dynamin-like GTPase 1 | -0.0245152 |
| SET | SET nuclear proto-oncogene | -0.0243961 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0240456 |
| BBX | bobby sox homolog (Drosophila) | -0.0240019 |
| RAI14 | retinoic acid induced 14 | -0.0237469 |
| MAP4 | microtubule-associated protein 4 | -0.0235712 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0234971 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0234746 |
| OPTN | optineurin | -0.0232162 |
| TMEM263 | transmembrane protein 263 | -0.0231862 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0230274 |
| TPM4 | tropomyosin 4 | -0.0230086 |
