| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Glycyrrhizic acid_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.129381 |
| EFNA5 | ephrin-A5 | 0.126955 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.101676 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0898289 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0836197 |
| PGK1 | phosphoglycerate kinase 1 | 0.0779638 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0762743 |
| MCL1 | myeloid cell leukemia 1 | 0.0702771 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0699103 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.06848 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0658222 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0651045 |
| ACTG1 | actin gamma 1 | 0.0649883 |
| FN1 | fibronectin 1 | 0.0580074 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0577543 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0560497 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0530751 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0522729 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0517584 |
| PKM | pyruvate kinase, muscle | 0.0508098 |
| FLNA | filamin A, alpha | 0.0492186 |
| NBAS | neuroblastoma amplified sequence | 0.0481784 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0474347 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0458473 |
| PTEN | phosphatase and tensin homolog | 0.0445629 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0438138 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0433705 |
| WDR43 | WD repeat domain 43 | 0.0420657 |
| NUP58 | nucleoporin 58 | 0.0412639 |
| RPL9 | ribosomal protein L9 | 0.0402574 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0385464 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0377705 |
| ATP13A3 | ATPase type 13A3 | 0.0371559 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0365958 |
| RPL13A | ribosomal protein L13a | 0.0362981 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0358374 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0352202 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0351871 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0338938 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0331022 |
| POTEF | POTE ankyrin domain family, member F | 0.032911 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0325964 |
| LAMA5 | laminin, alpha 5 | 0.0325838 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0324678 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.032376 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0321797 |
| ANXA5 | annexin A5 | 0.0316134 |
| SRPK2 | SRSF protein kinase 2 | 0.0315243 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0313631 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0313306 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0311029 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0309439 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0307736 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0306179 |
| RUNX1 | runt-related transcription factor 1 | 0.0305884 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0302862 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0298454 |
| ZNF292 | zinc finger protein 292 | 0.0295287 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0292856 |
| S100A6 | S100 calcium binding protein A6 | 0.0289445 |
| PDE10A | phosphodiesterase 10A | 0.0288689 |
| TCERG1 | transcription elongation regulator 1 | 0.0288155 |
| RAI1 | retinoic acid induced 1 | 0.0284671 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0284245 |
| PLCB4 | phospholipase C, beta 4 | 0.0283937 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0281928 |
| RPL23 | ribosomal protein L23 | 0.0281585 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0277036 |
| DNER | delta/notch-like EGF repeat containing | 0.0276865 |
| ZNF207 | zinc finger protein 207 | 0.0274165 |
| NONO | non-POU domain containing, octamer-binding | 0.0272344 |
| GOLGA4 | golgin A4 | 0.0271791 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0269654 |
| LDHA | lactate dehydrogenase A | 0.0268017 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0264959 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0264496 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0262828 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.025969 |
| CDC73 | cell division cycle 73 | 0.0259604 |
| FLNB | filamin B, beta | 0.025946 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0258598 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0257196 |
| CCNL1 | cyclin L1 | 0.025708 |
| HELZ | helicase with zinc finger | 0.0256287 |
| RPS2 | ribosomal protein S2 | 0.0252612 |
| SFTPA2 | surfactant protein A2 | 0.0251722 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0248762 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0248432 |
| NCKAP1 | NCK-associated protein 1 | 0.0247827 |
| SPAG9 | sperm associated antigen 9 | 0.0247495 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0246948 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) | 0.0245307 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.024473 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0240693 |
| HMGA1 | high mobility group AT-hook 1 | 0.0233599 |
| MSN | moesin | 0.0233328 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0230955 |
| CTBP2 | C-terminal binding protein 2 | 0.0230617 |
| AFG2A | AFG2 AAA ATPase homolog A | 0.0230457 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0230137 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.211588 |
| FTL | ferritin, light polypeptide | -0.188687 |
| TMSB10 | thymosin beta 10 | -0.180691 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.148976 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.129408 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0990037 |
| VIM | vimentin | -0.0928745 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0927445 |
| RPL31 | ribosomal protein L31 | -0.0875111 |
| PM20D1 | peptidase M20 domain containing 1 | -0.078028 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0776267 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0766769 |
| PTMA | prothymosin, alpha | -0.0763238 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.07047 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0670669 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0638941 |
| RPS24 | ribosomal protein S24 | -0.0634943 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0617722 |
| MYOF | myoferlin | -0.0581733 |
| TXNRD1 | thioredoxin reductase 1 | -0.0578654 |
| RPS12 | ribosomal protein S12 | -0.0571138 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0528733 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0504988 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0500748 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0497205 |
| RPS3 | ribosomal protein S3 | -0.0494841 |
| INHBA | inhibin, beta A | -0.0493828 |
| VCL | vinculin | -0.0463836 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0458484 |
| RPS17 | ribosomal protein S17 | -0.0443847 |
| PCBP3 | poly(rC) binding protein 3 | -0.0443189 |
| RPL26 | ribosomal protein L26 | -0.0433712 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0430962 |
| RPL19 | ribosomal protein L19 | -0.0425437 |
| CANX | calnexin | -0.0400095 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0393976 |
| RPL32 | ribosomal protein L32 | -0.0374243 |
| IER3 | immediate early response 3 | -0.0373721 |
| RPLP1 | ribosomal protein, large, P1 | -0.0366593 |
| ATXN1 | ataxin 1 | -0.036245 |
| KYNU | kynureninase | -0.035385 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0353749 |
| GRAMD1B | GRAM domain containing 1B | -0.034949 |
| RPL12 | ribosomal protein L12 | -0.0339565 |
| RPS5 | ribosomal protein S5 | -0.0338017 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0338013 |
| RPL7A | ribosomal protein L7a | -0.0334656 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0329925 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0316339 |
| RPS8 | ribosomal protein S8 | -0.0315626 |
| PRKD3 | protein kinase D3 | -0.0312659 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0312103 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0305183 |
| MAP7 | microtubule-associated protein 7 | -0.0301993 |
| AHNAK | AHNAK nucleoprotein | -0.029629 |
| RPS27A | ribosomal protein S27a | -0.0291463 |
| EGR1 | early growth response 1 | -0.0291363 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0290436 |
| RAB3B | RAB3B, member RAS oncogene family | -0.0289217 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0288196 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0286717 |
| SRGN | serglycin | -0.028607 |
| RGS2 | regulator of G-protein signaling 2 | -0.0283666 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0281504 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0278315 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0276936 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.027185 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0263698 |
| TPM4 | tropomyosin 4 | -0.0257619 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0254539 |
| RIGI | RNA sensor RIG-I | -0.0250555 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0249925 |
| CCDC68 | coiled-coil domain containing 68 | -0.0248715 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0247836 |
| EZR | ezrin | -0.0247632 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0245319 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0245206 |
| S100A10 | S100 calcium binding protein A10 | -0.0241479 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0241302 |
| RPL36A | ribosomal protein L36a | -0.0237023 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0236479 |
| GNAS | GNAS complex locus | -0.023562 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0233118 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0232873 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0231003 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0230021 |
| DST | dystonin | -0.0229452 |
| BMERB1 | bMERB domain containing 1 | -0.0227294 |
| TMSB4X | thymosin beta 4, X-linked | -0.022728 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0224702 |
| ALPK2 | alpha-kinase 2 | -0.0224559 |
| LSAMP | limbic system-associated membrane protein | -0.0224105 |
| RPL37A | ribosomal protein L37a | -0.0222927 |
| RPL5 | ribosomal protein L5 | -0.0222684 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.022183 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0214695 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0213567 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0210476 |
| PTGR1 | prostaglandin reductase 1 | -0.021 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0209796 |
