Glycyrrhizic acid_NCI-H596 Gene Set
Genes
57 genes differentially expressed following the Glycyrrhizic acid_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PABPC1
|
poly(A) binding protein, cytoplasmic 1
|
0.316886
|
|
KMT2E
|
lysine (K)-specific methyltransferase 2E
|
0.227617
|
|
GAPDH
|
glyceraldehyde-3-phosphate dehydrogenase
|
0.224895
|
|
PTMA
|
prothymosin, alpha
|
0.195723
|
|
FTH1
|
ferritin, heavy polypeptide 1
|
0.187595
|
|
TNPO1
|
transportin 1
|
0.163015
|
|
HSP90AA1
|
heat shock protein 90kDa alpha (cytosolic), class A member 1
|
0.160678
|
|
ZNF292
|
zinc finger protein 292
|
0.15331
|
|
NAMPT
|
nicotinamide phosphoribosyltransferase
|
0.149729
|
|
YWHAZ
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
|
0.147653
|
|
RBPJ
|
recombination signal binding protein for immunoglobulin kappa J region
|
0.142145
|
|
ANXA2
|
annexin A2
|
0.10496
|
|
PRRC2C
|
proline-rich coiled-coil 2C
|
0.098081
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
0.0742652
|
|
P4HB
|
prolyl 4-hydroxylase, beta polypeptide
|
0.0593057
|
|
RTN4
|
reticulon 4
|
0.0569359
|
|
PGK1
|
phosphoglycerate kinase 1
|
0.0557962
|
|
LDHA
|
lactate dehydrogenase A
|
0.051309
|
|
UBC
|
ubiquitin C
|
0.0494962
|
|
SERPINE1
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
|
0.043878
|
|
EFNA5
|
ephrin-A5
|
0.0411509
|
|
MT2A
|
metallothionein 2A
|
0.0401164
|
|
ACTG1
|
actin gamma 1
|
0.0330341
|
|
ENO1
|
enolase 1, (alpha)
|
0.031534
|
|
RPS6
|
ribosomal protein S6
|
0.0261273
|
|
NDRG1
|
N-myc downstream regulated 1
|
0.0219473
|
|
RPS3
|
ribosomal protein S3
|
0.0214458
|
|
DSCAM
|
Down syndrome cell adhesion molecule
|
0.0213438
|
|
RPL23
|
ribosomal protein L23
|
0.0111682
|
|
ELL2
|
elongation factor, RNA polymerase II, 2
|
0.00796046
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HERC4
|
HECT and RLD domain containing E3 ubiquitin protein ligase 4
|
-0.223415
|
|
COL5A2
|
collagen, type V, alpha 2
|
-0.177735
|
|
RIGI
|
RNA sensor RIG-I
|
-0.161753
|
|
JMJD1C
|
jumonji domain containing 1C
|
-0.15858
|
|
GBE1
|
glucan (1,4-alpha-), branching enzyme 1
|
-0.144577
|
|
AKAP12
|
A kinase (PRKA) anchor protein 12
|
-0.134551
|
|
NF1
|
neurofibromin 1
|
-0.132209
|
|
MMAB
|
methylmalonic aciduria (cobalamin deficiency) cblB type
|
-0.115231
|
|
TMSB10
|
thymosin beta 10
|
-0.114546
|
|
ASPH
|
aspartate beta-hydroxylase
|
-0.114282
|
|
PKM
|
pyruvate kinase, muscle
|
-0.111193
|
|
STC1
|
stanniocalcin 1
|
-0.106251
|
|
ITGB1
|
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
|
-0.104216
|
|
VIM
|
vimentin
|
-0.0946887
|
|
FN1
|
fibronectin 1
|
-0.0842784
|
|
HSPA5
|
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
|
-0.0664371
|
|
IMMP2L
|
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
|
-0.0561118
|
|
DST
|
dystonin
|
-0.055714
|
|
GPC6
|
glypican 6
|
-0.0526387
|
|
HSP90B1
|
heat shock protein 90kDa beta (Grp94), member 1
|
-0.0457399
|
|
TPT1
|
tumor protein, translationally-controlled 1
|
-0.0333303
|
|
FNDC3B
|
fibronectin type III domain containing 3B
|
-0.0323947
|
|
TRIO
|
trio Rho guanine nucleotide exchange factor
|
-0.0308929
|
|
B2M
|
beta-2-microglobulin
|
-0.0174846
|
|
ZBTB20
|
zinc finger and BTB domain containing 20
|
-0.0103468
|
|
AHNAK
|
AHNAK nucleoprotein
|
-0.0103369
|
|
RUNX1
|
runt-related transcription factor 1
|
-0.00718989
|
