| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glycyrrhizic acid_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0937278 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0839742 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0744399 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0738609 |
| LAMB3 | laminin, beta 3 | 0.073561 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0715659 |
| PTK2 | protein tyrosine kinase 2 | 0.0676367 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.067065 |
| NUP58 | nucleoporin 58 | 0.0658139 |
| PGK1 | phosphoglycerate kinase 1 | 0.0656434 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.065474 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0590097 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0576114 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0547268 |
| ATP13A3 | ATPase type 13A3 | 0.0524826 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0523871 |
| STC1 | stanniocalcin 1 | 0.0517851 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0513456 |
| USP3 | ubiquitin specific peptidase 3 | 0.0510683 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.050723 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0505708 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0502717 |
| TXNRD1 | thioredoxin reductase 1 | 0.0499016 |
| TPD52 | tumor protein D52 | 0.0497443 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0496215 |
| RASA2 | RAS p21 protein activator 2 | 0.0475219 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0461488 |
| ZNF292 | zinc finger protein 292 | 0.0448586 |
| PKM | pyruvate kinase, muscle | 0.0442706 |
| WDR43 | WD repeat domain 43 | 0.0433724 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0432413 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0432236 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0418531 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0414766 |
| FOXJ3 | forkhead box J3 | 0.0413424 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0409962 |
| NCKAP1 | NCK-associated protein 1 | 0.0404372 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0399375 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0397367 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0376112 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0374282 |
| CLTC | clathrin, heavy chain (Hc) | 0.0370828 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0368753 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0367541 |
| COG5 | component of oligomeric golgi complex 5 | 0.036649 |
| SRPK2 | SRSF protein kinase 2 | 0.0365156 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0364496 |
| OGA | O-GlcNAcase | 0.036304 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0362051 |
| SNX9 | sorting nexin 9 | 0.035853 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0349421 |
| CDK17 | cyclin-dependent kinase 17 | 0.0347651 |
| ARFGEF3 | ARFGEF family member 3 | 0.0345268 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0344868 |
| RPL4 | ribosomal protein L4 | 0.0344769 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0344331 |
| RLF | rearranged L-myc fusion | 0.0343493 |
| FLNA | filamin A, alpha | 0.0339023 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0336681 |
| CCNL1 | cyclin L1 | 0.0334409 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0334074 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0332967 |
| NBAS | neuroblastoma amplified sequence | 0.0330808 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0327142 |
| ANXA5 | annexin A5 | 0.032469 |
| C1ORF52 | chromosome 1 open reading frame 52 | 0.0324582 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0322874 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | 0.0321444 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0320837 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0319333 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0317597 |
| UBE3A | ubiquitin protein ligase E3A | 0.0317207 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0312907 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0310286 |
| YEATS2 | YEATS domain containing 2 | 0.0310139 |
| TOP1 | topoisomerase (DNA) I | 0.0308099 |
| RBM33 | RNA binding motif protein 33 | 0.0307617 |
| SBF2 | SET binding factor 2 | 0.0307119 |
| RTN4 | reticulon 4 | 0.0306532 |
| GOLGA4 | golgin A4 | 0.0305719 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0304242 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0303832 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.0303763 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0302577 |
| CDC73 | cell division cycle 73 | 0.0302543 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0300984 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0300883 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0299422 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0298744 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.029749 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0297118 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0296654 |
| CD68 | CD68 molecule | 0.0296311 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.029523 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0295196 |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor | 0.0294715 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0294035 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0291023 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0290924 |
| CALU | calumenin | 0.0289061 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.186072 |
| FRMD6 | FERM domain containing 6 | -0.170945 |
| ZNF438 | zinc finger protein 438 | -0.126449 |
| NABP1 | nucleic acid binding protein 1 | -0.108614 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.098832 |
| HMGA2 | high mobility group AT-hook 2 | -0.0928276 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0879859 |
| MT2A | metallothionein 2A | -0.0793712 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.076285 |
| SP100 | SP100 nuclear antigen | -0.0706568 |
| INTS6 | integrator complex subunit 6 | -0.0617468 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0576704 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0548347 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0546793 |
| ASPH | aspartate beta-hydroxylase | -0.0532129 |
| NAV3 | neuron navigator 3 | -0.0528783 |
| HDAC9 | histone deacetylase 9 | -0.0520297 |
| TMSB10 | thymosin beta 10 | -0.0509573 |
| MTAP | methylthioadenosine phosphorylase | -0.049347 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.048508 |
| RPS6 | ribosomal protein S6 | -0.0483579 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0451705 |
| FHIT | fragile histidine triad | -0.0444083 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0434108 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0426424 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0418702 |
| RAD51B | RAD51 paralog B | -0.0418208 |
| BNC2 | basonuclin 2 | -0.0412813 |
| FTL | ferritin, light polypeptide | -0.0392543 |
| RPS8 | ribosomal protein S8 | -0.0372729 |
| DGKI | diacylglycerol kinase, iota | -0.0367784 |
| AHNAK | AHNAK nucleoprotein | -0.0367543 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0358668 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0350273 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0346442 |
| MYRFL | myelin regulatory factor-like | -0.0343775 |
| NAV2 | neuron navigator 2 | -0.033757 |
| RPS3 | ribosomal protein S3 | -0.0332671 |
| MSH4 | mutS homolog 4 | -0.0319239 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0318674 |
| AEBP2 | AE binding protein 2 | -0.0318126 |
| RPL7A | ribosomal protein L7a | -0.0312859 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0304689 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0301399 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.030109 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0295672 |
| RPS19 | ribosomal protein S19 | -0.0294253 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0293498 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0290978 |
| DST | dystonin | -0.029018 |
| RCOR1 | REST corepressor 1 | -0.0288981 |
| EFNB2 | ephrin-B2 | -0.0285414 |
| RPLP1 | ribosomal protein, large, P1 | -0.0280715 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0278247 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0275763 |
| SGMS2 | sphingomyelin synthase 2 | -0.0275609 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.027542 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0274089 |
| RPS12 | ribosomal protein S12 | -0.0270942 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0257284 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0249606 |
| DIAPH2 | diaphanous-related formin 2 | -0.0248437 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0248038 |
| ANK2 | ankyrin 2, neuronal | -0.024458 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0243865 |
| RPS29 | ribosomal protein S29 | -0.0242695 |
| RPL34 | ribosomal protein L34 | -0.024194 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.0241727 |
| RPS24 | ribosomal protein S24 | -0.0241727 |
| DENND1A | DENN/MADD domain containing 1A | -0.0237304 |
| RASAL2 | RAS protein activator like 2 | -0.0235294 |
| CAST | calpastatin | -0.023216 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0230617 |
| EGR1 | early growth response 1 | -0.0230488 |
| RPLP2 | ribosomal protein, large, P2 | -0.0230141 |
| PLSCR1 | phospholipid scramblase 1 | -0.0224227 |
| RPL5 | ribosomal protein L5 | -0.0222307 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0220472 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0218344 |
| RPL31 | ribosomal protein L31 | -0.0217433 |
| EXOC4 | exocyst complex component 4 | -0.021296 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0209749 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0202759 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 | -0.0200396 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0199217 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) | -0.0197926 |
| CCDC91 | coiled-coil domain containing 91 | -0.0195582 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0193741 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0193595 |
| RPS23 | ribosomal protein S23 | -0.0192696 |
| RPL36 | ribosomal protein L36 | -0.0192462 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0191239 |
| RIGI | RNA sensor RIG-I | -0.0190725 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.018992 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0188893 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0188429 |
| RPS27A | ribosomal protein S27a | -0.0186397 |
| TRIM44 | tripartite motif containing 44 | -0.0183812 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0182015 |
| HDAC4 | histone deacetylase 4 | -0.0181718 |
