| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Glycyrrhizic acid_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0912441 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0886391 |
| PKM | pyruvate kinase, muscle | 0.0781679 |
| NUP58 | nucleoporin 58 | 0.0635081 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0625084 |
| EGR1 | early growth response 1 | 0.0560985 |
| PGK1 | phosphoglycerate kinase 1 | 0.0526113 |
| CPE | carboxypeptidase E | 0.0481412 |
| NAV2 | neuron navigator 2 | 0.0459328 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0453027 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0445164 |
| CCNL1 | cyclin L1 | 0.0434783 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0430436 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0428891 |
| JAM3 | junctional adhesion molecule 3 | 0.041444 |
| FAM13A | family with sequence similarity 13, member A | 0.0412094 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.04053 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0398666 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0394714 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0346536 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0332707 |
| POTEF | POTE ankyrin domain family, member F | 0.0330494 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0327495 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0326846 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0326436 |
| FAM162A | family with sequence similarity 162, member A | 0.0314278 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0303954 |
| DHFR | dihydrofolate reductase | 0.0301781 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0299724 |
| PCBP2 | poly(rC) binding protein 2 | 0.0296903 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0283915 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.028387 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0276319 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.027334 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0272209 |
| DTNA | dystrobrevin, alpha | 0.0266784 |
| INTS1 | integrator complex subunit 1 | 0.0264996 |
| CA8 | carbonic anhydrase VIII | 0.024887 |
| SIK3 | SIK family kinase 3 | 0.0247252 |
| NONO | non-POU domain containing, octamer-binding | 0.024676 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0246359 |
| WDR45B | WD repeat domain 45B | 0.024635 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0245808 |
| FAT1 | FAT atypical cadherin 1 | 0.0240474 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0238629 |
| HDGF | hepatoma-derived growth factor | 0.0237975 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0237594 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0237259 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0235663 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0235189 |
| SFPQ | splicing factor proline/glutamine-rich | 0.023501 |
| ZNF207 | zinc finger protein 207 | 0.0234995 |
| RORA | RAR-related orphan receptor A | 0.0234265 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0229127 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0225899 |
| PFN1 | profilin 1 | 0.0223532 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0222035 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0216886 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0216099 |
| BRD2 | bromodomain containing 2 | 0.0215734 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | 0.0215214 |
| AZIN1 | antizyme inhibitor 1 | 0.021214 |
| RCOR1 | REST corepressor 1 | 0.0211249 |
| CD24 | CD24 molecule | 0.0210099 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0208843 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0208707 |
| TPD52 | tumor protein D52 | 0.0206927 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0205575 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0204956 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0203789 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0203746 |
| PER2 | period circadian clock 2 | 0.0202295 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0202251 |
| HOMER1 | homer scaffolding protein 1 | 0.0201368 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0199144 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0199046 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0198883 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0197041 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0196368 |
| ENO1 | enolase 1, (alpha) | 0.0195674 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0192273 |
| EP400 | E1A binding protein p400 | 0.0192176 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0190484 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0188595 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0188282 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0186844 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.018613 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0185064 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.018477 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0182934 |
| CKB | creatine kinase, brain | 0.018118 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0181095 |
| LDHA | lactate dehydrogenase A | 0.0181089 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0180335 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0179821 |
| MSN | moesin | 0.017822 |
| VGF | VGF nerve growth factor inducible | 0.0177759 |
| NCKAP1 | NCK-associated protein 1 | 0.0177433 |
| RNF145 | ring finger protein 145 | 0.0176922 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0176131 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.140986 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.103185 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0947499 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0939711 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.071159 |
| PDE10A | phosphodiesterase 10A | -0.0711536 |
| FTL | ferritin, light polypeptide | -0.0683806 |
| RPL26 | ribosomal protein L26 | -0.0670611 |
| SMYD3 | SET and MYND domain containing 3 | -0.0666833 |
| RPS3 | ribosomal protein S3 | -0.0661249 |
| MT2A | metallothionein 2A | -0.0646636 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0636784 |
| TENM1 | teneurin transmembrane protein 1 | -0.0632771 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0626489 |
| GPC6 | glypican 6 | -0.0625263 |
| RPS8 | ribosomal protein S8 | -0.0589599 |
| TMSB10 | thymosin beta 10 | -0.0554247 |
| RPS21 | ribosomal protein S21 | -0.0540476 |
| CALCA | calcitonin-related polypeptide alpha | -0.0537373 |
| NRG1 | neuregulin 1 | -0.0533375 |
| WWOX | WW domain containing oxidoreductase | -0.0524343 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0511182 |
| RPL11 | ribosomal protein L11 | -0.0509801 |
| RPL37A | ribosomal protein L37a | -0.049617 |
| RPLP1 | ribosomal protein, large, P1 | -0.0482058 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0481216 |
| SNTG1 | syntrophin, gamma 1 | -0.0450049 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0448968 |
| RPS27A | ribosomal protein S27a | -0.0446837 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0443793 |
| RPL31 | ribosomal protein L31 | -0.0442019 |
| RPL19 | ribosomal protein L19 | -0.0435467 |
| TMSB4X | thymosin beta 4, X-linked | -0.0434385 |
| GPHN | gephyrin | -0.0433382 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0424138 |
| RPL32 | ribosomal protein L32 | -0.0414197 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0413333 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0406569 |
| RIGI | RNA sensor RIG-I | -0.040079 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0398764 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0397967 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0394019 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0386336 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0384194 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0383311 |
| RPL35 | ribosomal protein L35 | -0.0380535 |
| RPL5 | ribosomal protein L5 | -0.0380378 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0373416 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0372898 |
| EFNA5 | ephrin-A5 | -0.0372868 |
| CANX | calnexin | -0.0371605 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0364027 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.035545 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0354661 |
| RIT2 | Ras-like without CAAX 2 | -0.0352971 |
| LSAMP | limbic system-associated membrane protein | -0.0349521 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0348757 |
| PCBP3 | poly(rC) binding protein 3 | -0.0338699 |
| RPS12 | ribosomal protein S12 | -0.0337829 |
| RPS19 | ribosomal protein S19 | -0.0330143 |
| GPC5 | glypican 5 | -0.0329325 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.03287 |
| RPL38 | ribosomal protein L38 | -0.0328608 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0326219 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | -0.0325687 |
| RPL23 | ribosomal protein L23 | -0.0323853 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0321348 |
| RPS16 | ribosomal protein S16 | -0.0320926 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0320834 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0317915 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0317462 |
| RPL7A | ribosomal protein L7a | -0.03168 |
| RPL36AL | ribosomal protein L36a-like | -0.0316378 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0316063 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.0315093 |
| RPL37 | ribosomal protein L37 | -0.0314328 |
| FUS | FUS RNA binding protein | -0.031409 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0313786 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0313472 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0311622 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0309354 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0307969 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0307947 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0305093 |
| FHIT | fragile histidine triad | -0.0300115 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0299098 |
| RPL30 | ribosomal protein L30 | -0.0297855 |
| RPS6 | ribosomal protein S6 | -0.0297254 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.0297108 |
| FOXC1 | forkhead box C1 | -0.0296232 |
| KANTR | KDM5C adjacent non-coding transcript | -0.0295799 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0295263 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0294738 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0292793 |
| NCKAP5 | NCK-associated protein 5 | -0.0290165 |
| SYT1 | synaptotagmin I | -0.0289334 |
| RPL12 | ribosomal protein L12 | -0.0286864 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0284182 |
| KCTD8 | potassium channel tetramerization domain containing 8 | -0.0280041 |
| AGBL4 | ATP/GTP binding protein-like 4 | -0.0279952 |
