| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Glycyrrhizic acid_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.142872 |
| FNDC3B | fibronectin type III domain containing 3B | 0.136105 |
| LSAMP | limbic system-associated membrane protein | 0.116233 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.115635 |
| FLNA | filamin A, alpha | 0.0941709 |
| NLGN1 | neuroligin 1 | 0.0886614 |
| FMN1 | formin 1 | 0.073959 |
| NRG3 | neuregulin 3 | 0.0723302 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0685821 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0631337 |
| RAD51B | RAD51 paralog B | 0.0593366 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0537798 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.052568 |
| PKM | pyruvate kinase, muscle | 0.0499112 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0496816 |
| FHIT | fragile histidine triad | 0.0492797 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0489158 |
| NAV2 | neuron navigator 2 | 0.0488084 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0469918 |
| SFTPA2 | surfactant protein A2 | 0.0460673 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0459576 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0443845 |
| FRMD4A | FERM domain containing 4A | 0.0436794 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0422691 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0399831 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0387131 |
| FLNB | filamin B, beta | 0.0368373 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0364874 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0362428 |
| NOTCH2 | notch 2 | 0.035709 |
| MSI2 | musashi RNA-binding protein 2 | 0.0356544 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0353001 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0341255 |
| HDAC9 | histone deacetylase 9 | 0.0340175 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0337459 |
| PGK1 | phosphoglycerate kinase 1 | 0.033181 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0326668 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0324255 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.031811 |
| SEPTIN9 | septin 9 | 0.0302826 |
| FMNL2 | formin-like 2 | 0.0296865 |
| CTSB | cathepsin B | 0.0295572 |
| PRELID2 | PRELI domain containing 2 | 0.0290602 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0288289 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0283841 |
| STK10 | serine/threonine kinase 10 | 0.0275796 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.026178 |
| ATXN1 | ataxin 1 | 0.0259558 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0255997 |
| RUNX1 | runt-related transcription factor 1 | 0.0255507 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0252464 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.02478 |
| HDAC4 | histone deacetylase 4 | 0.0243706 |
| SMYD3 | SET and MYND domain containing 3 | 0.0240615 |
| CFAP20DC | CFAP20 domain containing | 0.0239449 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0239298 |
| YEATS2 | YEATS domain containing 2 | 0.0238965 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.023689 |
| ENTHD1 | ENTH domain containing 1 | 0.0226228 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.022512 |
| CCDC91 | coiled-coil domain containing 91 | 0.0222247 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0221724 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0221463 |
| EXOC4 | exocyst complex component 4 | 0.0221387 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0218641 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0218579 |
| PRKCE | protein kinase C, epsilon | 0.0213073 |
| SVIL | supervillin | 0.0212863 |
| NCOR2 | nuclear receptor corepressor 2 | 0.021093 |
| MSN | moesin | 0.0210833 |
| CCNL1 | cyclin L1 | 0.021063 |
| SMAD3 | SMAD family member 3 | 0.0208378 |
| CLEC2D | C-type lectin domain family 2, member D | 0.0207629 |
| TENM3 | teneurin transmembrane protein 3 | 0.0207139 |
| CADM1 | cell adhesion molecule 1 | 0.0206664 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0205126 |
| TCF20 | transcription factor 20 (AR1) | 0.0204658 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0203273 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0202867 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0201121 |
| USP22 | ubiquitin specific peptidase 22 | 0.0200001 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0199533 |
| MCL1 | myeloid cell leukemia 1 | 0.0199252 |
| KLHL29 | kelch-like family member 29 | 0.0198322 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0197062 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0197013 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0195555 |
| TNNC1 | troponin C type 1 (slow) | 0.019406 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0193446 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0191869 |
| EP300 | E1A binding protein p300 | 0.0190532 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0190162 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0189867 |
| KAZN | kazrin, periplakin interacting protein | 0.0189396 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0188712 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0188007 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0187099 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0186735 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.018575 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.018528 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.240741 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112335 |
| FTL | ferritin, light polypeptide | -0.0987285 |
| PTMA | prothymosin, alpha | -0.092788 |
| RPS3 | ribosomal protein S3 | -0.0815741 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0799177 |
| TMSB10 | thymosin beta 10 | -0.0765251 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0705515 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0653648 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0573305 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0560015 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0543576 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0541283 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0518765 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0455448 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0449488 |
| CENPF | centromere protein F, 350/400kDa | -0.0436983 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0426391 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0422338 |
| CANX | calnexin | -0.0411958 |
| RPLP1 | ribosomal protein, large, P1 | -0.040533 |
| RPL32 | ribosomal protein L32 | -0.0372652 |
| RPL31 | ribosomal protein L31 | -0.0368867 |
| RPS6 | ribosomal protein S6 | -0.0366354 |
| RPL12 | ribosomal protein L12 | -0.0345295 |
| RPL35A | ribosomal protein L35a | -0.0343804 |
| GOLGA4 | golgin A4 | -0.0339568 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0335999 |
| RPS24 | ribosomal protein S24 | -0.0334028 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0332067 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0327174 |
| MT2A | metallothionein 2A | -0.0312634 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0308525 |
| RPS8 | ribosomal protein S8 | -0.0301606 |
| FRMD5 | FERM domain containing 5 | -0.0298909 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0265245 |
| RPL11 | ribosomal protein L11 | -0.0264393 |
| RPL23 | ribosomal protein L23 | -0.0263933 |
| RPL34 | ribosomal protein L34 | -0.0258633 |
| ANLN | anillin, actin binding protein | -0.0257299 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0255796 |
| TXNRD1 | thioredoxin reductase 1 | -0.0254424 |
| TFG | TRK-fused gene | -0.025353 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0249047 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0248758 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0247625 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0245353 |
| B2M | beta-2-microglobulin | -0.02452 |
| TKT | transketolase | -0.0244687 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0239266 |
| RPS4X | ribosomal protein S4, X-linked | -0.0239061 |
| CCDC47 | coiled-coil domain containing 47 | -0.0238065 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0237645 |
| RPS12 | ribosomal protein S12 | -0.0236661 |
| MORF4L2 | mortality factor 4 like 2 | -0.0235461 |
| S100A9 | S100 calcium binding protein A9 | -0.0233837 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0233129 |
| NPR2 | natriuretic peptide receptor 2 | -0.023266 |
| H3-3B | H3.3 histone B | -0.0231198 |
| QKI | QKI, KH domain containing, RNA binding | -0.0230497 |
| CLINT1 | clathrin interactor 1 | -0.0230424 |
| TENM1 | teneurin transmembrane protein 1 | -0.0230404 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0230137 |
| RPS14 | ribosomal protein S14 | -0.0225662 |
| MAP4 | microtubule-associated protein 4 | -0.0224153 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0222873 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0221032 |
| RPL19 | ribosomal protein L19 | -0.0220814 |
| TPM4 | tropomyosin 4 | -0.0219368 |
| CBX3 | chromobox homolog 3 | -0.0217649 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0216762 |
| RPS5 | ribosomal protein S5 | -0.0216268 |
| RPS27A | ribosomal protein S27a | -0.021609 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0215609 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0214361 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -0.0214244 |
| SEPTIN7 | septin 7 | -0.0213855 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0208464 |
| S100A10 | S100 calcium binding protein A10 | -0.0206624 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0205189 |
| RLF | rearranged L-myc fusion | -0.0205052 |
| RPLP2 | ribosomal protein, large, P2 | -0.020486 |
| NOP58 | NOP58 ribonucleoprotein | -0.0204362 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0202903 |
| MKI67 | marker of proliferation Ki-67 | -0.0202353 |
| RPL36A | ribosomal protein L36a | -0.0202197 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0200908 |
| HMGB2 | high mobility group box 2 | -0.0200261 |
| STMN1 | stathmin 1 | -0.0199527 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0199484 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0198776 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.019858 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0197765 |
| RRBP1 | ribosome binding protein 1 | -0.0195863 |
| RPL5 | ribosomal protein L5 | -0.01924 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0192167 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0191953 |
| ENO1 | enolase 1, (alpha) | -0.0189999 |
| TRIM33 | tripartite motif containing 33 | -0.0189616 |
| RPS16 | ribosomal protein S16 | -0.0185993 |
