Glycyrrhizic acid_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Glycyrrhizic acid perturbation in SNU-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Glycyrrhizic acid_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
EEF1G eukaryotic translation elongation factor 1 gamma 0.137133
FLNB filamin B, beta 0.0893197
ECT2 epithelial cell transforming 2 0.0851294
CCNL1 cyclin L1 0.0798096
EEF2 eukaryotic translation elongation factor 2 0.069989
ZNF292 zinc finger protein 292 0.0698706
PGK1 phosphoglycerate kinase 1 0.0687946
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0684151
NBAS neuroblastoma amplified sequence 0.0656536
PKM pyruvate kinase, muscle 0.0522245
ADAM10 ADAM metallopeptidase domain 10 0.0519621
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0516626
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0515851
GOLGA4 golgin A4 0.0463163
NAMPT nicotinamide phosphoribosyltransferase 0.0454467
NUP58 nucleoporin 58 0.0441979
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0430129
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0430093
RTN4 reticulon 4 0.0428606
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0422265
ELOVL5 ELOVL fatty acid elongase 5 0.0418919
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0416598
B2M beta-2-microglobulin 0.040383
LOC112694756 uncharaterized LOC112694756 0.0398764
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0390039
TMEM41B transmembrane protein 41B 0.0385273
HMGA1 high mobility group AT-hook 1 0.0380325
BIRC6 baculoviral IAP repeat containing 6 0.0378058
WAC WW domain containing adaptor with coiled-coil 0.0372768
ADAM9 ADAM metallopeptidase domain 9 0.0370841
PDIA3 protein disulfide isomerase family A, member 3 0.0368987
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.0366127
RBM39 RNA binding motif protein 39 0.0356105
SBF2 SET binding factor 2 0.0355125
GSK3B glycogen synthase kinase 3 beta 0.0354403
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0348454
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0347969
ZCCHC7 zinc finger, CCHC domain containing 7 0.0345247
PICALM phosphatidylinositol binding clathrin assembly protein 0.0344112
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0343967
SREBF2 sterol regulatory element binding transcription factor 2 0.0340538
PTK2 protein tyrosine kinase 2 0.0333248
CAMTA1 calmodulin binding transcription activator 1 0.0329169
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0325517
WDR43 WD repeat domain 43 0.0324536
LPP LIM domain containing preferred translocation partner in lipoma 0.0323403
FXR1 fragile X mental retardation, autosomal homolog 1 0.0322492
FNDC3B fibronectin type III domain containing 3B 0.0320186
YAP1 Yes-associated protein 1 0.0316358
MON2 MON2 homolog (S. cerevisiae) 0.0310786
PUM2 pumilio RNA-binding family member 2 0.0310736
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0307873
MT2A metallothionein 2A 0.0300306
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0299603
PYGB phosphorylase, glycogen; brain 0.0299497
NAV2 neuron navigator 2 0.02969
PTBP2 polypyrimidine tract binding protein 2 0.029536
YEATS2 YEATS domain containing 2 0.0293663
LDHA lactate dehydrogenase A 0.0289531
KDM6A lysine (K)-specific demethylase 6A 0.0285242
SEC31A SEC31 homolog A (S. cerevisiae) 0.0282814
KMT2E lysine (K)-specific methyltransferase 2E 0.0277934
COG5 component of oligomeric golgi complex 5 0.0275861
ZNF207 zinc finger protein 207 0.0275186
TENT4A terminal nucleotidyltransferase 4A 0.0273524
SRRM2 serine/arginine repetitive matrix 2 0.0273014
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0272784
SFPQ splicing factor proline/glutamine-rich 0.0272146
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0271141
SRPK2 SRSF protein kinase 2 0.0267908
BRWD1 bromodomain and WD repeat domain containing 1 0.0267779
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0265423
FOXJ3 forkhead box J3 0.0264712
UBA6 ubiquitin-like modifier activating enzyme 6 0.0263477
RBM33 RNA binding motif protein 33 0.0253158
NONO non-POU domain containing, octamer-binding 0.0251133
TRIM25 tripartite motif containing 25 0.0249575
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0246758
ZMYM2 zinc finger, MYM-type 2 0.0245641
CD47 CD47 molecule 0.024534
TMEM39A transmembrane protein 39A 0.0243844
SPAG9 sperm associated antigen 9 0.0243245
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0243126
TFG TRK-fused gene 0.0241436
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0237419
RHBDD1 rhomboid domain containing 1 0.0235674
PCBP2 poly(rC) binding protein 2 0.023516
SPRED2 sprouty-related, EVH1 domain containing 2 0.0234193
TRA2B transformer 2 beta homolog (Drosophila) 0.0233306
POTEF POTE ankyrin domain family, member F 0.0231472
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0230944
MSI2 musashi RNA-binding protein 2 0.0229593
ATXN2L ataxin 2-like 0.0228865
SLMAP sarcolemma associated protein 0.0227433
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.022546
SETD5 SET domain containing 5 0.0222977
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0222273
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0220856
PTEN phosphatase and tensin homolog 0.0217122
ZNF644 zinc finger protein 644 0.0216704

decreased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha -0.362461
TPT1 tumor protein, translationally-controlled 1 -0.13843
AHNAK AHNAK nucleoprotein -0.13706
TMSB4X thymosin beta 4, X-linked -0.116549
RPS8 ribosomal protein S8 -0.112025
BMP10 bone morphogenetic protein 10 -0.105523
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.100871
RPL31 ribosomal protein L31 -0.0860428
PDE4B phosphodiesterase 4B, cAMP-specific -0.0851007
VCL vinculin -0.0714606
RPS6 ribosomal protein S6 -0.0699332
ARL4C ADP-ribosylation factor-like 4C -0.0616976
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0592659
FOXP1 forkhead box P1 -0.0581917
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0577053
RPS3 ribosomal protein S3 -0.0565534
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0565107
RPLP1 ribosomal protein, large, P1 -0.0541793
ANXA1 annexin A1 -0.0540008
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0529987
CCND1 cyclin D1 -0.052729
RPL26 ribosomal protein L26 -0.0523175
RPL19 ribosomal protein L19 -0.0519721
RPL35A ribosomal protein L35a -0.0509282
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0497145
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0489562
RPL12 ribosomal protein L12 -0.0474961
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0465084
RPS12 ribosomal protein S12 -0.0451105
IFI16 interferon, gamma-inducible protein 16 -0.0449218
RPL7A ribosomal protein L7a -0.0449144
RSL1D1 ribosomal L1 domain containing 1 -0.0448813
EZR ezrin -0.0438304
TMSB10 thymosin beta 10 -0.0422247
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0419979
KPNB1 karyopherin (importin) beta 1 -0.0415541
RPL5 ribosomal protein L5 -0.0414394
FTL ferritin, light polypeptide -0.0412604
TM4SF1 transmembrane 4 L six family member 1 -0.0409034
PDE4D phosphodiesterase 4D, cAMP-specific -0.0404719
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0397843
RPL32 ribosomal protein L32 -0.0394322
RPL37A ribosomal protein L37a -0.0391036
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0388613
NAP1L1 nucleosome assembly protein 1-like 1 -0.0388115
RPS27A ribosomal protein S27a -0.0383712
HSPB1 heat shock 27kDa protein 1 -0.0380256
ZMYND8 zinc finger, MYND-type containing 8 -0.0359129
RPS17 ribosomal protein S17 -0.0355279
EFNA5 ephrin-A5 -0.0355073
RPS24 ribosomal protein S24 -0.035251
RPL34 ribosomal protein L34 -0.0348792
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.0348496
S100A10 S100 calcium binding protein A10 -0.0347308
RPLP2 ribosomal protein, large, P2 -0.0346444
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0343345
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.033457
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0331303
GLI2 GLI family zinc finger 2 -0.03269
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -0.0323361
RPS25 ribosomal protein S25 -0.032061
TAS2R14 taste receptor, type 2, member 14 -0.031387
MYO5C myosin VC -0.0309075
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.030754
NBEA neurobeachin -0.0307463
SSBP2 single-stranded DNA binding protein 2 -0.0306592
GPATCH8 G patch domain containing 8 -0.0306307
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0305691
SP100 SP100 nuclear antigen -0.0300183
EBNA1BP2 EBNA1 binding protein 2 -0.0296823
RPS16 ribosomal protein S16 -0.0289373
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.0288269
TPM4 tropomyosin 4 -0.0282139
PDE7B phosphodiesterase 7B -0.0279904
GLI3 GLI family zinc finger 3 -0.0276357
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0270626
LOC102724023 ES1 protein homolog, mitochondrial -0.0267499
S100A4 S100 calcium binding protein A4 -0.0263441
CAMKMT calmodulin-lysine N-methyltransferase -0.0261505
RPL14 ribosomal protein L14 -0.0259884
RPS23 ribosomal protein S23 -0.0253588
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.0253159
TJP1 tight junction protein 1 -0.024858
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -0.0246859
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0246784
ZBTB38 zinc finger and BTB domain containing 38 -0.024579
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0243559
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0242575
MYL12B myosin, light chain 12B, regulatory -0.0240995
RPL18 ribosomal protein L18 -0.0238604
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0235885
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.023358
ZNF438 zinc finger protein 438 -0.0231234
CLIP1 CAP-GLY domain containing linker protein 1 -0.0230827
RPL36A ribosomal protein L36a -0.0230256
CANX calnexin -0.0225968
RPS14 ribosomal protein S14 -0.0225494
UNC13A unc-13 homolog A (C. elegans) -0.0224768
CCNI cyclin I -0.0222879
STAU1 staufen double-stranded RNA binding protein 1 -0.0222617