Glycyrrhizic acid_SW 900 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Glycyrrhizic acid perturbation in SW 900 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Glycyrrhizic acid_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FNDC3B fibronectin type III domain containing 3B 0.0745093
EEF1G eukaryotic translation elongation factor 1 gamma 0.0693388
NAMPT nicotinamide phosphoribosyltransferase 0.0690911
FTH1 ferritin, heavy polypeptide 1 0.0679489
CXCL8 chemokine (C-X-C motif) ligand 8 0.0674366
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0548837
TRIO trio Rho guanine nucleotide exchange factor 0.0547467
PKM pyruvate kinase, muscle 0.0511551
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0473198
FAT1 FAT atypical cadherin 1 0.0457466
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0408481
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0395366
HELZ helicase with zinc finger 0.039169
PGK1 phosphoglycerate kinase 1 0.0391235
SOD2 superoxide dismutase 2, mitochondrial 0.0371005
SMAD3 SMAD family member 3 0.0368705
AHR aryl hydrocarbon receptor 0.0362142
NUP58 nucleoporin 58 0.0356763
GOLGA4 golgin A4 0.0351131
TENT2 terminal nucleotidyltransferase 2 0.0329933
TMEM165 transmembrane protein 165 0.0326328
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0322614
LCORL ligand dependent nuclear receptor corepressor-like 0.032182
RPS21 ribosomal protein S21 0.031809
PPP1R15B protein phosphatase 1, regulatory subunit 15B 0.0317631
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0317267
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.030377
BIRC3 baculoviral IAP repeat containing 3 0.0298451
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0296717
AFDN afadin, adherens junction formation factor 0.0295657
ANXA5 annexin A5 0.0294985
SNX13 sorting nexin 13 0.028897
CLTC clathrin, heavy chain (Hc) 0.0284181
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.028155
ETNK1 ethanolamine kinase 1 0.0279874
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.027982
SPAG9 sperm associated antigen 9 0.0276146
RPL9 ribosomal protein L9 0.0273496
RNF145 ring finger protein 145 0.027244
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 0.0268236
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.0267198
RPL13A ribosomal protein L13a 0.0264084
OGA O-GlcNAcase 0.0261179
MARK3 MAP/microtubule affinity-regulating kinase 3 0.0261076
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.0260547
EPS8 epidermal growth factor receptor pathway substrate 8 0.0259357
PUM2 pumilio RNA-binding family member 2 0.0258835
PDIA3 protein disulfide isomerase family A, member 3 0.0258076
SUCO SUN domain containing ossification factor 0.0255862
NAP1L1 nucleosome assembly protein 1-like 1 0.0255742
MON2 MON2 homolog (S. cerevisiae) 0.0255436
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.025533
RICTOR RPTOR independent companion of MTOR, complex 2 0.0254473
FNIP1 folliculin interacting protein 1 0.0251705
RUNX1 runt-related transcription factor 1 0.0251007
PICALM phosphatidylinositol binding clathrin assembly protein 0.0250913
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0249484
CCNL1 cyclin L1 0.0248539
FLNA filamin A, alpha 0.0247902
BIRC6 baculoviral IAP repeat containing 6 0.0246084
FOXO3 forkhead box O3 0.0245388
CTBP2 C-terminal binding protein 2 0.0243516
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0242975
ZCCHC7 zinc finger, CCHC domain containing 7 0.0242223
TENT4A terminal nucleotidyltransferase 4A 0.0240914
RPL23 ribosomal protein L23 0.0240043
FAM13A family with sequence similarity 13, member A 0.0239556
APLP2 amyloid beta (A4) precursor-like protein 2 0.0233163
SRP54 signal recognition particle 54kDa 0.0232648
SEC23A Sec23 homolog A (S. cerevisiae) 0.0232609
WDR43 WD repeat domain 43 0.0230744
WTAP Wilms tumor 1 associated protein 0.0226218
GOLT1B golgi transport 1B 0.0225859
NBAS neuroblastoma amplified sequence 0.0225846
RBM39 RNA binding motif protein 39 0.0222174
SHB Src homology 2 domain containing adaptor protein B 0.021761
NIPBL Nipped-B homolog (Drosophila) 0.0214629
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.0210858
EYA1 EYA transcriptional coactivator and phosphatase 1 0.0210172
SLC41A2 solute carrier family 41 (magnesium transporter), member 2 0.0210051
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 0.0209113
UBA6 ubiquitin-like modifier activating enzyme 6 0.0208704
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0208492
RPL35A ribosomal protein L35a 0.0208184
RPL36 ribosomal protein L36 0.0206644
HDGF hepatoma-derived growth factor 0.0205339
FRYL FRY-like 0.0205037
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 0.0204974
KMT2E lysine (K)-specific methyltransferase 2E 0.0204672
BHLHE40 basic helix-loop-helix family, member e40 0.0204454
STRN3 striatin, calmodulin binding protein 3 0.020417
TFG TRK-fused gene 0.0202825
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.020217
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0202071
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0198416
SPDYA speedy/RINGO cell cycle regulator family member A 0.0198344
WAC WW domain containing adaptor with coiled-coil 0.0197309
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.0197269
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.0197232
KMT2C lysine (K)-specific methyltransferase 2C 0.0195811

decreased expression

Symbol Name Standardized Value
FN1 fibronectin 1 -0.1517
FTL ferritin, light polypeptide -0.106012
TMSB10 thymosin beta 10 -0.0883231
NRG1 neuregulin 1 -0.0800146
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0780828
NDRG1 N-myc downstream regulated 1 -0.0611844
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0592944
VCL vinculin -0.0545537
ASPH aspartate beta-hydroxylase -0.050835
TMEM156 transmembrane protein 156 -0.0507586
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0490126
HMGA2 high mobility group AT-hook 2 -0.045713
MAP1B microtubule-associated protein 1B -0.0443251
AKAP12 A kinase (PRKA) anchor protein 12 -0.0431353
TXNIP thioredoxin interacting protein -0.0402938
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0390646
GRB10 growth factor receptor-bound protein 10 -0.0346383
NTN4 netrin 4 -0.0333666
AHNAK AHNAK nucleoprotein -0.0331442
IFI6 interferon, alpha-inducible protein 6 -0.0325652
SYT1 synaptotagmin I -0.0320204
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.0306262
ELL2 elongation factor, RNA polymerase II, 2 -0.0303515
STC2 stanniocalcin 2 -0.0296785
IFI16 interferon, gamma-inducible protein 16 -0.0293355
PLIN2 perilipin 2 -0.0290695
TMEM131 transmembrane protein 131 -0.0282341
LOC102724023 ES1 protein homolog, mitochondrial -0.0281198
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0279015
STAT1 signal transducer and activator of transcription 1, 91kDa -0.027763
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0275823
IER3 immediate early response 3 -0.0255569
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0254902
SQSTM1 sequestosome 1 -0.025441
RPL31 ribosomal protein L31 -0.0251945
TPM4 tropomyosin 4 -0.0249272
LIMCH1 LIM and calponin homology domains 1 -0.0246868
ENO2 enolase 2 (gamma, neuronal) -0.0237685
CANX calnexin -0.0229762
PALLD palladin, cytoskeletal associated protein -0.0229548
TGFA transforming growth factor, alpha -0.0229106
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0229062
LRMDA leucine rich melanocyte differentiation associated -0.0228836
IFI27 interferon, alpha-inducible protein 27 -0.0228254
FNDC3A fibronectin type III domain containing 3A -0.0223131
SOX4 SRY (sex determining region Y)-box 4 -0.0222358
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0219489
MX2 MX dynamin-like GTPase 2 -0.0217634
ARHGAP5 Rho GTPase activating protein 5 -0.0217027
IFIH1 interferon induced with helicase C domain 1 -0.0216162
RAI14 retinoic acid induced 14 -0.0213072
TTC28 tetratricopeptide repeat domain 28 -0.0208955
OASL 2'-5'-oligoadenylate synthetase-like -0.020647
RPS12 ribosomal protein S12 -0.0205464
H1-0 H1.0 linker histone -0.0204441
NPC1 Niemann-Pick disease, type C1 -0.0204147
LTBP1 latent transforming growth factor beta binding protein 1 -0.0201273
TENM4 teneurin transmembrane protein 4 -0.0199047
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0195535
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0195011
SLC35F3 solute carrier family 35, member F3 -0.0192686
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0191311
FHIT fragile histidine triad -0.0189297
ETV1 ets variant 1 -0.018809
RIGI RNA sensor RIG-I -0.0188089
SFRP1 secreted frizzled-related protein 1 -0.0188007
TSHZ2 teashirt zinc finger homeobox 2 -0.0185427
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.018535
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0184017
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0183912
CCSER1 coiled-coil serine-rich protein 1 -0.0183577
TMSB4X thymosin beta 4, X-linked -0.0179404
BOD1L1 biorientation of chromosomes in cell division 1-like 1 -0.0177066
TSC22D1 TSC22 domain family, member 1 -0.0176675
FHL2 four and a half LIM domains 2 -0.0176128
VIM vimentin -0.0175989
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0172052
NPAS2 neuronal PAS domain protein 2 -0.0169294
TNS3 tensin 3 -0.0168225
DUSP6 dual specificity phosphatase 6 -0.0167903
IFI44L interferon-induced protein 44-like -0.0167063
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0165476
EGR1 early growth response 1 -0.016467
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -0.0164004
S100A10 S100 calcium binding protein A10 -0.0163745
AHNAK2 AHNAK nucleoprotein 2 -0.0163191
CST3 cystatin C -0.0161578
AREG amphiregulin -0.0160992
CTSB cathepsin B -0.0158791
AUTS2 autism susceptibility candidate 2 -0.0158407
IGFBP5 insulin-like growth factor binding protein 5 -0.0157286
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -0.0155573
NCOA7 nuclear receptor coactivator 7 -0.0155312
OSMR oncostatin M receptor -0.0154456
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0154245
FOXP1 forkhead box P1 -0.0152136
PXMP2 peroxisomal membrane protein 2, 22kDa -0.0151316
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0151315
SVIL supervillin -0.0151304
BICD1 bicaudal D homolog 1 (Drosophila) -0.0151164