| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Glycyrrhizic acid perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Glycyrrhizic acid_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0856354 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0733215 |
| HLA-B | major histocompatibility complex, class I, B | 0.0654396 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0634087 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.061951 |
| ACTG1 | actin gamma 1 | 0.0595673 |
| RPL35A | ribosomal protein L35a | 0.0571614 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0438585 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0422445 |
| FLNA | filamin A, alpha | 0.0406496 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0368275 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0347311 |
| IGF2 | insulin-like growth factor 2 | 0.0346187 |
| HMGA2 | high mobility group AT-hook 2 | 0.0344516 |
| RPL13A | ribosomal protein L13a | 0.0340017 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0338337 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0335184 |
| RPL37A | ribosomal protein L37a | 0.0333225 |
| INTS6 | integrator complex subunit 6 | 0.0327979 |
| VCL | vinculin | 0.0318928 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0305807 |
| RPS16 | ribosomal protein S16 | 0.0287825 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0285449 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0282425 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0267281 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0264577 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0259466 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0256723 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0256358 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0254426 |
| PKM | pyruvate kinase, muscle | 0.0251059 |
| EXT1 | exostosin glycosyltransferase 1 | 0.024555 |
| CABIN1 | calcineurin binding protein 1 | 0.0238016 |
| RPL31 | ribosomal protein L31 | 0.0234943 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0234254 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0231409 |
| EGFR | epidermal growth factor receptor | 0.0224926 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0221592 |
| RPS13 | ribosomal protein S13 | 0.0221216 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0217511 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0216963 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0210893 |
| MCL1 | myeloid cell leukemia 1 | 0.0210385 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0210363 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0210127 |
| KIAA1217 | KIAA1217 | 0.0207875 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0206624 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0206255 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0205276 |
| FN1 | fibronectin 1 | 0.0201053 |
| MSI2 | musashi RNA-binding protein 2 | 0.0201004 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0198529 |
| CTBP2 | C-terminal binding protein 2 | 0.0198188 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.019705 |
| SMYD3 | SET and MYND domain containing 3 | 0.0195506 |
| SNX14 | sorting nexin 14 | 0.0195079 |
| RAD51B | RAD51 paralog B | 0.0192752 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.019127 |
| USP15 | ubiquitin specific peptidase 15 | 0.0190283 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0190173 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0189986 |
| MRC2 | mannose receptor, C type 2 | 0.0188865 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0188861 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0188127 |
| MEIS1 | Meis homeobox 1 | 0.0187833 |
| GOLGB1 | golgin B1 | 0.018769 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0185879 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0185743 |
| MMP12 | matrix metallopeptidase 12 | 0.0185331 |
| NBEAL1 | neurobeachin-like 1 | 0.0184646 |
| DTNA | dystrobrevin, alpha | 0.0183185 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0181945 |
| COG5 | component of oligomeric golgi complex 5 | 0.0180722 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0180535 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0179812 |
| ATG7 | autophagy related 7 | 0.0179697 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0178925 |
| EGR1 | early growth response 1 | 0.0178168 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.01766 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0176135 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0176093 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0173694 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0172964 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0172438 |
| THBS1 | thrombospondin 1 | 0.0171803 |
| NBAS | neuroblastoma amplified sequence | 0.0171083 |
| BRD2 | bromodomain containing 2 | 0.0170797 |
| AEBP2 | AE binding protein 2 | 0.0169973 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0168018 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0163725 |
| FUS | FUS RNA binding protein | 0.0163344 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0159821 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0159802 |
| RPL30 | ribosomal protein L30 | 0.0159541 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0159034 |
| RPS29 | ribosomal protein S29 | 0.0157823 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0157331 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0157314 |
| MMP2 | matrix metallopeptidase 2 | 0.0156987 |
| CREBBP | CREB binding protein | 0.0155483 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.423123 |
| STC1 | stanniocalcin 1 | -0.174482 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.14304 |
| INHBA | inhibin, beta A | -0.114578 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0875475 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0857833 |
| COL1A2 | collagen, type I, alpha 2 | -0.0765695 |
| MYO10 | myosin X | -0.0763493 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0740672 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0729167 |
| EMP1 | epithelial membrane protein 1 | -0.0706804 |
| FAM13A | family with sequence similarity 13, member A | -0.0682155 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0655462 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0632347 |
| ASPH | aspartate beta-hydroxylase | -0.0610724 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0590301 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0580659 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0579978 |
| MMP1 | matrix metallopeptidase 1 | -0.0578503 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0557755 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0551558 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0551357 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0532609 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0524498 |
| AHNAK | AHNAK nucleoprotein | -0.0513624 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0480753 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0462592 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0459325 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0451386 |
| OXR1 | oxidation resistance 1 | -0.0446765 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0444422 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0424215 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0423576 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0402536 |
| TMSB4X | thymosin beta 4, X-linked | -0.0399136 |
| TMSB10 | thymosin beta 10 | -0.0394492 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0393409 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0393378 |
| ZNF292 | zinc finger protein 292 | -0.0393212 |
| CANX | calnexin | -0.0385887 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.03819 |
| IER3 | immediate early response 3 | -0.0361104 |
| CENPF | centromere protein F, 350/400kDa | -0.0356491 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0351352 |
| CAVIN1 | caveolae associated protein 1 | -0.0343438 |
| MAP1B | microtubule-associated protein 1B | -0.0338387 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0338197 |
| NDRG1 | N-myc downstream regulated 1 | -0.0335789 |
| FTL | ferritin, light polypeptide | -0.0329218 |
| SEPTIN11 | septin 11 | -0.0322485 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0321295 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0321006 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0315792 |
| CALU | calumenin | -0.030627 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.030446 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0301701 |
| MED13L | mediator complex subunit 13-like | -0.0299477 |
| RAI14 | retinoic acid induced 14 | -0.0298675 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0296913 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0292135 |
| MT2A | metallothionein 2A | -0.0281093 |
| YBX1 | Y box binding protein 1 | -0.0278401 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0273004 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.026738 |
| RTN4 | reticulon 4 | -0.0264671 |
| B2M | beta-2-microglobulin | -0.026331 |
| RUNX1 | runt-related transcription factor 1 | -0.0259961 |
| TPM4 | tropomyosin 4 | -0.0257852 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0255482 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0254541 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0251028 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0248541 |
| ADM | adrenomedullin | -0.0248468 |
| DST | dystonin | -0.0248229 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0247804 |
| TPM3 | tropomyosin 3 | -0.0245245 |
| RNF145 | ring finger protein 145 | -0.0241793 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0241074 |
| CCDC47 | coiled-coil domain containing 47 | -0.0237885 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0236056 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0236026 |
| S100A10 | S100 calcium binding protein A10 | -0.0229968 |
| H3-3B | H3.3 histone B | -0.0226444 |
| OGA | O-GlcNAcase | -0.0225778 |
| FRMD4A | FERM domain containing 4A | -0.0225057 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0223476 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0221442 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0219751 |
| CCDC102B | coiled-coil domain containing 102B | -0.0217766 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0216528 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.021528 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0210618 |
| PCBP2 | poly(rC) binding protein 2 | -0.0209519 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0209422 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0208385 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0207406 |
| ETV3 | ets variant 3 | -0.0207015 |
| EHD2 | EH-domain containing 2 | -0.020558 |
| PLPP3 | phospholipid phosphatase 3 | -0.020495 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0204305 |
