| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.294477 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.108421 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.104321 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0960712 |
| MT2A | metallothionein 2A | 0.0892733 |
| PLAT | plasminogen activator, tissue | 0.089253 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0841617 |
| CENPF | centromere protein F, 350/400kDa | 0.0780589 |
| ASPH | aspartate beta-hydroxylase | 0.0683962 |
| CD44 | CD44 molecule (Indian blood group) | 0.0643928 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0639606 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0624878 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0612387 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0604283 |
| PRRC2C | proline-rich coiled-coil 2C | 0.05964 |
| LMNA | lamin A/C | 0.0589833 |
| TPM3 | tropomyosin 3 | 0.0536888 |
| HDAC9 | histone deacetylase 9 | 0.0530777 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0523074 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0516881 |
| DST | dystonin | 0.048724 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.04548 |
| GOLGB1 | golgin B1 | 0.0454023 |
| MKI67 | marker of proliferation Ki-67 | 0.0450976 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.045031 |
| RPS3 | ribosomal protein S3 | 0.0449196 |
| PTMA | prothymosin, alpha | 0.0448102 |
| FLNA | filamin A, alpha | 0.043103 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0423262 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0410997 |
| AHNAK | AHNAK nucleoprotein | 0.0409394 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0405428 |
| NAV2 | neuron navigator 2 | 0.0400887 |
| SMC4 | structural maintenance of chromosomes 4 | 0.040049 |
| TPR | translocated promoter region, nuclear basket protein | 0.039978 |
| CALR | calreticulin | 0.039635 |
| GOLGA4 | golgin A4 | 0.0389662 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0384013 |
| SEPTIN9 | septin 9 | 0.0380899 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0375833 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.037523 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0369944 |
| PODXL | podocalyxin-like | 0.036508 |
| RND3 | Rho family GTPase 3 | 0.0359914 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0359362 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0359158 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0357942 |
| FAM107B | family with sequence similarity 107, member B | 0.0356322 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0355106 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0351623 |
| MSN | moesin | 0.0348773 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0342765 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0340667 |
| RPS2 | ribosomal protein S2 | 0.0330076 |
| B2M | beta-2-microglobulin | 0.0327965 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0327414 |
| CAVIN1 | caveolae associated protein 1 | 0.0323676 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.032058 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0317495 |
| RPL37A | ribosomal protein L37a | 0.0315713 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0311112 |
| RPS6 | ribosomal protein S6 | 0.0306028 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0300887 |
| EZR | ezrin | 0.0299047 |
| RPL26 | ribosomal protein L26 | 0.0297503 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0292208 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0289858 |
| RPS8 | ribosomal protein S8 | 0.0289298 |
| RRM2 | ribonucleotide reductase M2 | 0.028382 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0281597 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0280385 |
| CDH13 | cadherin 13 | 0.0279534 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.027567 |
| SET | SET nuclear proto-oncogene | 0.0270896 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0270839 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0268979 |
| BRD2 | bromodomain containing 2 | 0.0268127 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0265321 |
| TLE4 | transducin-like enhancer of split 4 | 0.0264148 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0263987 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0263904 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0263225 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0262076 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0261276 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0260246 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0258391 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0256676 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0254393 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0252388 |
| PRELID2 | PRELI domain containing 2 | 0.0250786 |
| SFTPA2 | surfactant protein A2 | 0.024811 |
| BCL2L1 | BCL2-like 1 | 0.0247056 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0245689 |
| CANX | calnexin | 0.0245196 |
| TAPBP | TAP binding protein (tapasin) | 0.0245044 |
| KIF5B | kinesin family member 5B | 0.0244354 |
| POTEF | POTE ankyrin domain family, member F | 0.0243921 |
| RRBP1 | ribosome binding protein 1 | 0.024156 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0240447 |
| SEPTIN7 | septin 7 | 0.0237885 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.239859 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.12345 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.119285 |
| LOX | lysyl oxidase | -0.107062 |
| FBN1 | fibrillin 1 | -0.100232 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0964549 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0925121 |
| THBS2 | thrombospondin 2 | -0.0827554 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0808148 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.078939 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.077435 |
| SUCNR1 | succinate receptor 1 | -0.0704127 |
| VIM | vimentin | -0.0690921 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.068289 |
| COL1A2 | collagen, type I, alpha 2 | -0.0659222 |
| FN1 | fibronectin 1 | -0.0651913 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0573286 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.055416 |
| MEIS2 | Meis homeobox 2 | -0.0502154 |
| TMSB10 | thymosin beta 10 | -0.0500873 |
| LOXL2 | lysyl oxidase-like 2 | -0.0481511 |
| MX2 | MX dynamin-like GTPase 2 | -0.0468018 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0460288 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0455852 |
| S100A6 | S100 calcium binding protein A6 | -0.0422182 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.041902 |
| UBC | ubiquitin C | -0.0415876 |
| ANXA2 | annexin A2 | -0.0405907 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0399883 |
| RIGI | RNA sensor RIG-I | -0.0397656 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0385129 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0372146 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0371926 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0370506 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0357168 |
| COL5A2 | collagen, type V, alpha 2 | -0.0356899 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0356699 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0355135 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0343933 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0334487 |
| AUTS2 | autism susceptibility candidate 2 | -0.0334302 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0326973 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.032061 |
| TPM1 | tropomyosin 1 (alpha) | -0.0316993 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0309505 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0308831 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0308336 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0306758 |
| CCND1 | cyclin D1 | -0.0306608 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0297937 |
| NAV1 | neuron navigator 1 | -0.0294969 |
| TAGLN2 | transgelin 2 | -0.0293627 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0279023 |
| RUNX1 | runt-related transcription factor 1 | -0.0277568 |
| HLA-E | major histocompatibility complex, class I, E | -0.0274864 |
| MSI2 | musashi RNA-binding protein 2 | -0.0273782 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0273252 |
| WTAP | Wilms tumor 1 associated protein | -0.0273012 |
| FRMD5 | FERM domain containing 5 | -0.0272944 |
| ZNF207 | zinc finger protein 207 | -0.0268194 |
| SP3 | Sp3 transcription factor | -0.0264205 |
| PKM | pyruvate kinase, muscle | -0.0263244 |
| HLA-C | major histocompatibility complex, class I, C | -0.0261889 |
| TNS3 | tensin 3 | -0.0260848 |
| GNAS | GNAS complex locus | -0.0257954 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0256783 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0255591 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0253902 |
| JAZF1 | JAZF zinc finger 1 | -0.0252612 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0251229 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0246883 |
| IER3 | immediate early response 3 | -0.02445 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0238399 |
| DCLK2 | doublecortin-like kinase 2 | -0.0236053 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0235343 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0232705 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0232652 |
| BSG | basigin (Ok blood group) | -0.023265 |
| SBF2 | SET binding factor 2 | -0.0232181 |
| TMOD1 | tropomodulin 1 | -0.0228913 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0227678 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0226167 |
| PXDN | peroxidasin | -0.0225013 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0224349 |
| AFAP1 | actin filament associated protein 1 | -0.0224235 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0224115 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0221498 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0221303 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0216843 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0215713 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0215435 |
| TUBB | tubulin, beta class I | -0.0212434 |
| SPAG9 | sperm associated antigen 9 | -0.0212309 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0209998 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0207427 |
| KRT81 | keratin 81, type II | -0.0203093 |
| TRIM56 | tripartite motif containing 56 | -0.0202627 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.020243 |
| INSIG1 | insulin induced gene 1 | -0.0200958 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0199589 |
