| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.181209 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.164432 |
| AREG | amphiregulin | 0.163273 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.156506 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.142614 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.114126 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0994565 |
| VIM | vimentin | 0.0918977 |
| DST | dystonin | 0.0880557 |
| ASPH | aspartate beta-hydroxylase | 0.0871807 |
| RPS3 | ribosomal protein S3 | 0.0830076 |
| YBX3 | Y box binding protein 3 | 0.0806173 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0762665 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0758429 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0734103 |
| PCDH7 | protocadherin 7 | 0.0678387 |
| RRM2 | ribonucleotide reductase M2 | 0.0676325 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0631136 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0600312 |
| RTN4 | reticulon 4 | 0.0591165 |
| NLGN1 | neuroligin 1 | 0.0538474 |
| CENPF | centromere protein F, 350/400kDa | 0.053587 |
| ANXA1 | annexin A1 | 0.0528845 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0517024 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.051184 |
| JMJD1C | jumonji domain containing 1C | 0.050063 |
| EZR | ezrin | 0.0479352 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0478734 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0465804 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0464273 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0449867 |
| HMGA2 | high mobility group AT-hook 2 | 0.0444959 |
| MKI67 | marker of proliferation Ki-67 | 0.0443514 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0440884 |
| TPM3 | tropomyosin 3 | 0.0436815 |
| ADIPOR2 | adiponectin receptor 2 | 0.0430721 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0430154 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0426061 |
| IPO7 | importin 7 | 0.0409038 |
| TMEM41B | transmembrane protein 41B | 0.040196 |
| TPI1 | triosephosphate isomerase 1 | 0.0400251 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0397441 |
| RPS6 | ribosomal protein S6 | 0.0397209 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0387609 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0386296 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.038156 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.038142 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0380771 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0364316 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0363503 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.036166 |
| RACK1 | receptor for activated C kinase 1 | 0.0359919 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0352114 |
| TPR | translocated promoter region, nuclear basket protein | 0.0349611 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0349088 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0342718 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0340432 |
| RPS8 | ribosomal protein S8 | 0.0334357 |
| INTS6 | integrator complex subunit 6 | 0.0334056 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0326977 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0320756 |
| RPS12 | ribosomal protein S12 | 0.0319964 |
| PTMA | prothymosin, alpha | 0.031762 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0317271 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0315148 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0311767 |
| CAVIN1 | caveolae associated protein 1 | 0.031067 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0308971 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0308781 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0304551 |
| ENO1 | enolase 1, (alpha) | 0.030089 |
| PRDX1 | peroxiredoxin 1 | 0.0300221 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0299287 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0298945 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0295313 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0292406 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0290923 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0290209 |
| AHNAK | AHNAK nucleoprotein | 0.0289977 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0288856 |
| RASAL2 | RAS protein activator like 2 | 0.0286512 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0283004 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0282273 |
| GOLGB1 | golgin B1 | 0.0279829 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0279213 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0278694 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0278449 |
| MTAP | methylthioadenosine phosphorylase | 0.0277535 |
| CALR | calreticulin | 0.0275884 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.027449 |
| TOP1 | topoisomerase (DNA) I | 0.0273667 |
| BRD2 | bromodomain containing 2 | 0.0272583 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0270865 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0269036 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0267695 |
| CCDC47 | coiled-coil domain containing 47 | 0.0266843 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0265494 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0263726 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0262195 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0261802 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113149 |
| MGAT4C | MGAT4 family, member C | -0.0765928 |
| TMEM123 | transmembrane protein 123 | -0.0477284 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0461404 |
| NHSL1 | NHS-like 1 | -0.0421335 |
| HMGA1 | high mobility group AT-hook 1 | -0.0381905 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0367525 |
| CPOX | coproporphyrinogen oxidase | -0.034527 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0344753 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0326514 |
| USP34 | ubiquitin specific peptidase 34 | -0.0324694 |
| KLHL24 | kelch-like family member 24 | -0.0322195 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0317 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0315897 |
| ZNF292 | zinc finger protein 292 | -0.0306384 |
| TENM3 | teneurin transmembrane protein 3 | -0.030492 |
| ZNF207 | zinc finger protein 207 | -0.0300768 |
| YEATS2 | YEATS domain containing 2 | -0.0296383 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0289639 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0286617 |
| R3HDM1 | R3H domain containing 1 | -0.0283869 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0280505 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0276412 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0246995 |
| BCHE | butyrylcholinesterase | -0.0241444 |
| PFN1 | profilin 1 | -0.0238057 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0230977 |
| COG5 | component of oligomeric golgi complex 5 | -0.0224821 |
| SETD5 | SET domain containing 5 | -0.0222754 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0221088 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0217282 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0209417 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.020834 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0206468 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0202338 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0201641 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0201261 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0200132 |
| CDC42SE2 | CDC42 small effector 2 | -0.0199367 |
| MED13L | mediator complex subunit 13-like | -0.0198473 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.019769 |
| CEP192 | centrosomal protein 192kDa | -0.0197058 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0196996 |
| HLA-A | major histocompatibility complex, class I, A | -0.0196662 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0195834 |
| NUP58 | nucleoporin 58 | -0.019194 |
| CDK19 | cyclin-dependent kinase 19 | -0.019121 |
| WASF2 | WAS protein family, member 2 | -0.018978 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0188253 |
| RPLP1 | ribosomal protein, large, P1 | -0.018764 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.018671 |
| S100A6 | S100 calcium binding protein A6 | -0.018479 |
| FBXO11 | F-box protein 11 | -0.0181723 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0181518 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0180804 |
| KSR2 | kinase suppressor of ras 2 | -0.0180042 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0176758 |
| ZFP64 | ZFP64 zinc finger protein | -0.0176462 |
| SYT1 | synaptotagmin I | -0.0171838 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0171234 |
| TUBA1B | tubulin, alpha 1b | -0.0167075 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.016648 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | -0.0165727 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0165401 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0164154 |
| XPO1 | exportin 1 | -0.0164042 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0163172 |
| TSPAN5 | tetraspanin 5 | -0.0163131 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0161328 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0160585 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.015705 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0156721 |
| RNF13 | ring finger protein 13 | -0.015667 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0156583 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0156317 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0155357 |
| RAB10 | RAB10, member RAS oncogene family | -0.0154542 |
| CDK17 | cyclin-dependent kinase 17 | -0.0154479 |
| CDC27 | cell division cycle 27 | -0.0153326 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0152952 |
| CCNL1 | cyclin L1 | -0.015282 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0152641 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0152007 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0151089 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0150704 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0150083 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0150048 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0150017 |
| RPS5 | ribosomal protein S5 | -0.0149899 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0149604 |
| TMEM131 | transmembrane protein 131 | -0.014793 |
| RPS16 | ribosomal protein S16 | -0.0147852 |
| RPL8 | ribosomal protein L8 | -0.0147281 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0146397 |
| ZNF652 | zinc finger protein 652 | -0.0144695 |
| PCNX1 | pecanex 1 | -0.0144611 |
| THOC1 | THO complex 1 | -0.0144499 |
| WDR41 | WD repeat domain 41 | -0.0143381 |
| GLG1 | golgi glycoprotein 1 | -0.0141148 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0141127 |
