| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Goserelin (acetate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.136444 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.11418 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.111711 |
| NAV2 | neuron navigator 2 | 0.106802 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.106671 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.096305 |
| NDRG1 | N-myc downstream regulated 1 | 0.0779318 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0769189 |
| AHNAK | AHNAK nucleoprotein | 0.0733192 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.061339 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0612455 |
| FMNL2 | formin-like 2 | 0.0606469 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0578465 |
| RPS6 | ribosomal protein S6 | 0.0573765 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0570331 |
| RNF213 | ring finger protein 213 | 0.0560649 |
| SEPTIN9 | septin 9 | 0.055276 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0531449 |
| CTBP2 | C-terminal binding protein 2 | 0.0521855 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0510886 |
| MYOF | myoferlin | 0.050513 |
| PLEC | plectin | 0.050499 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0488604 |
| CD44 | CD44 molecule (Indian blood group) | 0.0487782 |
| APP | amyloid beta (A4) precursor protein | 0.0479098 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0474926 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0459393 |
| SMAD3 | SMAD family member 3 | 0.0456875 |
| B2M | beta-2-microglobulin | 0.0432245 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.04161 |
| JAK1 | Janus kinase 1 | 0.041237 |
| FTL | ferritin, light polypeptide | 0.0407687 |
| SFTPA2 | surfactant protein A2 | 0.0405208 |
| GOLGB1 | golgin B1 | 0.0399475 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.039592 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0394983 |
| MSN | moesin | 0.0390544 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0389675 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0386203 |
| MT2A | metallothionein 2A | 0.0379185 |
| TPM3 | tropomyosin 3 | 0.0374102 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.037286 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0371175 |
| LOXL2 | lysyl oxidase-like 2 | 0.0369944 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0358958 |
| OPTN | optineurin | 0.035424 |
| PAX8 | paired box 8 | 0.0351238 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.034106 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0340221 |
| ANO6 | anoctamin 6 | 0.0338802 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0338145 |
| APOL1 | apolipoprotein L, 1 | 0.0335357 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0331917 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0331172 |
| INTS6 | integrator complex subunit 6 | 0.0329268 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0328769 |
| LYST | lysosomal trafficking regulator | 0.0315625 |
| RPS4X | ribosomal protein S4, X-linked | 0.0315312 |
| GPC5 | glypican 5 | 0.0309573 |
| LAMB1 | laminin, beta 1 | 0.0307867 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0305762 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0302059 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0300393 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0296014 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0293941 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0290135 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0285632 |
| HDAC9 | histone deacetylase 9 | 0.0284601 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0284445 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0283926 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0282017 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0280384 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0275625 |
| ITSN2 | intersectin 2 | 0.027546 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0273227 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0272609 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0270889 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0270264 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0268478 |
| DST | dystonin | 0.0266318 |
| RPS8 | ribosomal protein S8 | 0.0266237 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0265843 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0265591 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0264772 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0263489 |
| EGFR | epidermal growth factor receptor | 0.0263474 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0258454 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.025742 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0256226 |
| DSPP | dentin sialophosphoprotein | 0.0255879 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.025368 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0252088 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0251358 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0251043 |
| RPS3 | ribosomal protein S3 | 0.0248928 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0247595 |
| NCKAP1 | NCK-associated protein 1 | 0.024741 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.024652 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.024345 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0240592 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0828493 |
| VIM | vimentin | -0.0811254 |
| GPC6 | glypican 6 | -0.0796658 |
| GLIS3 | GLIS family zinc finger 3 | -0.0787704 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0753452 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0750172 |
| CP | ceruloplasmin (ferroxidase) | -0.0712845 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0693174 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0627538 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0592799 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0585681 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0578218 |
| PALLD | palladin, cytoskeletal associated protein | -0.0555927 |
| FRMD4A | FERM domain containing 4A | -0.0541943 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0499588 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0445924 |
| STK17A | serine/threonine kinase 17a | -0.0420565 |
| SCFD2 | sec1 family domain containing 2 | -0.041603 |
| TGFB2 | transforming growth factor, beta 2 | -0.0415931 |
| CALU | calumenin | -0.0413549 |
| CTSD | cathepsin D | -0.041184 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.041053 |
| VCL | vinculin | -0.0410492 |
| POTEF | POTE ankyrin domain family, member F | -0.0393474 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0390474 |
| TPM4 | tropomyosin 4 | -0.0381444 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0378737 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.037356 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.037001 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0369827 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0357957 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0342225 |
| HSPB1 | heat shock 27kDa protein 1 | -0.033891 |
| FAT1 | FAT atypical cadherin 1 | -0.0330761 |
| GDF15 | growth differentiation factor 15 | -0.03281 |
| RPS24 | ribosomal protein S24 | -0.0320678 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0317202 |
| MYADM | myeloid-associated differentiation marker | -0.0317083 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0315954 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0311172 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0305491 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0305237 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0303238 |
| FN1 | fibronectin 1 | -0.0298155 |
| S100A6 | S100 calcium binding protein A6 | -0.0295103 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0293521 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.02925 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0291789 |
| TPM1 | tropomyosin 1 (alpha) | -0.0290264 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0286544 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0284548 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0284091 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0281742 |
| PLIN2 | perilipin 2 | -0.0281337 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0280449 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0278126 |
| RIC8B | RIC8 guanine nucleotide exchange factor B | -0.0275538 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0274666 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0273524 |
| PTH2R | parathyroid hormone 2 receptor | -0.0268055 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0267542 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0264677 |
| CDK13 | cyclin-dependent kinase 13 | -0.0262911 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0261524 |
| LIMA1 | LIM domain and actin binding 1 | -0.0255444 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0255307 |
| INSIG1 | insulin induced gene 1 | -0.0252696 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0250346 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0248545 |
| NRP1 | neuropilin 1 | -0.024772 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0245621 |
| CREB5 | cAMP responsive element binding protein 5 | -0.024164 |
| OXR1 | oxidation resistance 1 | -0.0241395 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0236754 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0234801 |
| EHBP1 | EH domain binding protein 1 | -0.0231608 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0229575 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0228571 |
| TUBB | tubulin, beta class I | -0.0226673 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0224367 |
| ANXA4 | annexin A4 | -0.0223919 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | -0.0222914 |
| GDA | guanine deaminase | -0.0222613 |
| TNS3 | tensin 3 | -0.0221448 |
| NUP58 | nucleoporin 58 | -0.0220959 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0218896 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0218217 |
| HM13 | histocompatibility (minor) 13 | -0.0214277 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0213177 |
| RTN4 | reticulon 4 | -0.0212791 |
| COG5 | component of oligomeric golgi complex 5 | -0.0210111 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0208861 |
| TUBA1B | tubulin, alpha 1b | -0.0207312 |
| RPS5 | ribosomal protein S5 | -0.0206058 |
| GLG1 | golgi glycoprotein 1 | -0.0205785 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0205751 |
| GNAS | GNAS complex locus | -0.0204856 |
| SRPK2 | SRSF protein kinase 2 | -0.0204265 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0204107 |
| PTGR1 | prostaglandin reductase 1 | -0.020308 |
