| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Goserelin (acetate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.40748 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0997286 |
| AHNAK | AHNAK nucleoprotein | 0.0809649 |
| VIM | vimentin | 0.0662391 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0648699 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0643636 |
| KLF6 | Kruppel-like factor 6 | 0.0623018 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0582208 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0576438 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.056673 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0558231 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0557035 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0550591 |
| RPS3 | ribosomal protein S3 | 0.0538144 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0535961 |
| FAM107B | family with sequence similarity 107, member B | 0.0509639 |
| RPS19 | ribosomal protein S19 | 0.0503779 |
| RPS6 | ribosomal protein S6 | 0.0425212 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0395125 |
| USP47 | ubiquitin specific peptidase 47 | 0.0384756 |
| TMSB10 | thymosin beta 10 | 0.0380242 |
| RND3 | Rho family GTPase 3 | 0.0372277 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0368228 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0364786 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0363242 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0356265 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0356054 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0354711 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0353302 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0343384 |
| LAMC2 | laminin, gamma 2 | 0.0342117 |
| EZR | ezrin | 0.0340343 |
| FMNL2 | formin-like 2 | 0.0339631 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0336799 |
| GOLGB1 | golgin B1 | 0.0336136 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0334179 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0330738 |
| ACTN4 | actinin, alpha 4 | 0.0327805 |
| BMP6 | bone morphogenetic protein 6 | 0.0325419 |
| TOP1 | topoisomerase (DNA) I | 0.032099 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0315211 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0314675 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0309677 |
| RPL35A | ribosomal protein L35a | 0.030713 |
| MT1X | metallothionein 1X | 0.0296113 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.029517 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0294299 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0288742 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0285093 |
| LMO7 | LIM domain 7 | 0.0284926 |
| RPL13A | ribosomal protein L13a | 0.0282521 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0278806 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0277985 |
| RPL26 | ribosomal protein L26 | 0.0269751 |
| CAVIN1 | caveolae associated protein 1 | 0.0269735 |
| RPS27A | ribosomal protein S27a | 0.0269704 |
| LAMB3 | laminin, beta 3 | 0.025838 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0257038 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0255062 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0250056 |
| DUSP16 | dual specificity phosphatase 16 | 0.0248515 |
| PTMA | prothymosin, alpha | 0.0248069 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0246982 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0246403 |
| STC1 | stanniocalcin 1 | 0.0240446 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0240011 |
| RPS4X | ribosomal protein S4, X-linked | 0.0239104 |
| H1-0 | H1.0 linker histone | 0.023767 |
| DSCAM | Down syndrome cell adhesion molecule | 0.023604 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0235174 |
| SERINC1 | serine incorporator 1 | 0.0234866 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0229791 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0227768 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0227658 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0226501 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0221618 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.022152 |
| YBX3 | Y box binding protein 3 | 0.0218625 |
| LMNA | lamin A/C | 0.0217667 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0217624 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0215926 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0215514 |
| BRD4 | bromodomain containing 4 | 0.0212596 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0212465 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0208016 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0207973 |
| RACK1 | receptor for activated C kinase 1 | 0.0207603 |
| RPS21 | ribosomal protein S21 | 0.0206062 |
| HMGA2 | high mobility group AT-hook 2 | 0.0204442 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0204196 |
| OGA | O-GlcNAcase | 0.0203548 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.020283 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0202027 |
| RASA2 | RAS p21 protein activator 2 | 0.0199922 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0199887 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0199139 |
| RRBP1 | ribosome binding protein 1 | 0.0199079 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0199071 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0197581 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0197263 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.134905 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.126493 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.108325 |
| PDE10A | phosphodiesterase 10A | -0.0954772 |
| PKM | pyruvate kinase, muscle | -0.0917999 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0843652 |
| CA12 | carbonic anhydrase XII | -0.0835601 |
| NDRG1 | N-myc downstream regulated 1 | -0.0793541 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0778484 |
| TXNRD1 | thioredoxin reductase 1 | -0.0775538 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0754534 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0652454 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0641366 |
| AUTS2 | autism susceptibility candidate 2 | -0.0622148 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0591595 |
| FTL | ferritin, light polypeptide | -0.0585412 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0572058 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0559214 |
| EHBP1 | EH domain binding protein 1 | -0.0554242 |
| FNDC3B | fibronectin type III domain containing 3B | -0.055405 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0519224 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0510934 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0507262 |
| TPM1 | tropomyosin 1 (alpha) | -0.0499287 |
| TNS3 | tensin 3 | -0.0494595 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0491334 |
| SBF2 | SET binding factor 2 | -0.0486155 |
| HMGA1 | high mobility group AT-hook 1 | -0.0483869 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.047471 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0474334 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0461782 |
| RNF213 | ring finger protein 213 | -0.0443361 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0433654 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0425922 |
| POTEF | POTE ankyrin domain family, member F | -0.0422642 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0409731 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0388824 |
| GPC6 | glypican 6 | -0.0387552 |
| VCL | vinculin | -0.0385089 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0383338 |
| NRG1 | neuregulin 1 | -0.0380998 |
| USP3 | ubiquitin specific peptidase 3 | -0.0378763 |
| SPAG9 | sperm associated antigen 9 | -0.0375892 |
| MYADM | myeloid-associated differentiation marker | -0.0375295 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0367504 |
| ATG7 | autophagy related 7 | -0.0366926 |
| ANXA4 | annexin A4 | -0.0365397 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0364178 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.036045 |
| RPS2 | ribosomal protein S2 | -0.0354892 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0354074 |
| RIN2 | Ras and Rab interactor 2 | -0.0351128 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.035047 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0348403 |
| EREG | epiregulin | -0.0344584 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0339047 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0338808 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0336663 |
| SMAD3 | SMAD family member 3 | -0.0330733 |
| TKT | transketolase | -0.0330701 |
| DSTN | destrin (actin depolymerizing factor) | -0.0328211 |
| ASPH | aspartate beta-hydroxylase | -0.0322422 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0314147 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0311761 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0310605 |
| MAP1B | microtubule-associated protein 1B | -0.0310437 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0310325 |
| PLSCR1 | phospholipid scramblase 1 | -0.0307151 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0305633 |
| NRP1 | neuropilin 1 | -0.0301072 |
| RAD51B | RAD51 paralog B | -0.0300282 |
| USP34 | ubiquitin specific peptidase 34 | -0.0297732 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0297654 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0294734 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.028879 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0288373 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0288338 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0286097 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0283971 |
| PTK2 | protein tyrosine kinase 2 | -0.0281596 |
| ZNF207 | zinc finger protein 207 | -0.028049 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0277425 |
| PCED1B | PC-esterase domain containing 1B | -0.0273104 |
| FA2H | fatty acid 2-hydroxylase | -0.0270428 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0269915 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0267816 |
| GOLGA4 | golgin A4 | -0.0264829 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0261084 |
| ZNF609 | zinc finger protein 609 | -0.0259543 |
| NUP58 | nucleoporin 58 | -0.025836 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.025631 |
| PFN1 | profilin 1 | -0.0254069 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0250032 |
| TRIM25 | tripartite motif containing 25 | -0.0247237 |
| LAMA5 | laminin, alpha 5 | -0.0246105 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0245167 |
| EFNA5 | ephrin-A5 | -0.0243831 |
| MYO1B | myosin IB | -0.0241996 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0241548 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0241389 |
