| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MGP | matrix Gla protein | 0.145911 |
| VEGFA | vascular endothelial growth factor A | 0.122261 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.10531 |
| MEST | mesoderm specific transcript | 0.103347 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0943969 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0813843 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0753284 |
| RPS3 | ribosomal protein S3 | 0.070186 |
| FNIP1 | folliculin interacting protein 1 | 0.0687122 |
| PDE10A | phosphodiesterase 10A | 0.0661375 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0650446 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0614966 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0594187 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0585495 |
| GSE1 | Gse1 coiled-coil protein | 0.0555992 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0531609 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0509795 |
| RPS12 | ribosomal protein S12 | 0.0502924 |
| BRD4 | bromodomain containing 4 | 0.050225 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0500675 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0484563 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0475283 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0474974 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.047107 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0461128 |
| CENPF | centromere protein F, 350/400kDa | 0.0460135 |
| ZNF292 | zinc finger protein 292 | 0.0457543 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0453582 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0445431 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0442877 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0429489 |
| RPS2 | ribosomal protein S2 | 0.0428692 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0425323 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0424223 |
| RPS6 | ribosomal protein S6 | 0.0421755 |
| ENAH | enabled homolog (Drosophila) | 0.0411691 |
| SFTPA2 | surfactant protein A2 | 0.0411106 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0410835 |
| ARRDC3 | arrestin domain containing 3 | 0.0410716 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0409755 |
| NIN | ninein (GSK3B interacting protein) | 0.0404004 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0403683 |
| RPL3 | ribosomal protein L3 | 0.0387265 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0376253 |
| QKI | QKI, KH domain containing, RNA binding | 0.0368749 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0367394 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0352727 |
| SLK | STE20-like kinase | 0.0352715 |
| NCKAP1 | NCK-associated protein 1 | 0.0352598 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0343787 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0342757 |
| MATR3 | matrin 3 | 0.0339856 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.033135 |
| RPL26 | ribosomal protein L26 | 0.0327506 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0327363 |
| ATP11A | ATPase, class VI, type 11A | 0.0322479 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0319397 |
| RPL14 | ribosomal protein L14 | 0.0317379 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0314734 |
| BCOR | BCL6 corepressor | 0.0313497 |
| PHIP | pleckstrin homology domain interacting protein | 0.0303346 |
| IPO7 | importin 7 | 0.0299331 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0297024 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0291171 |
| ADM | adrenomedullin | 0.0286468 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0286444 |
| MYOF | myoferlin | 0.0286348 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0286119 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0281897 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0280656 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0280652 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0278923 |
| PHF3 | PHD finger protein 3 | 0.0278511 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0275381 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0273195 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0272613 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0269386 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0268238 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0266148 |
| RACK1 | receptor for activated C kinase 1 | 0.0263866 |
| RBM33 | RNA binding motif protein 33 | 0.0263414 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0261944 |
| JMJD1C | jumonji domain containing 1C | 0.0259 |
| SMAP1 | small ArfGAP 1 | 0.0257943 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0257556 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0255884 |
| ANO6 | anoctamin 6 | 0.0254452 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0252994 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0252601 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0250627 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0250462 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0249539 |
| FAM168A | family with sequence similarity 168, member A | 0.0246186 |
| H1-2 | H1.2 linker histone, cluster member | 0.0245262 |
| CORO1C | coronin, actin binding protein, 1C | 0.0244768 |
| ZNF148 | zinc finger protein 148 | 0.0244566 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.024373 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0243153 |
| H1-4 | H1.4 linker histone, cluster member | 0.0242001 |
| WBP11 | WW domain binding protein 11 | 0.0241886 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.191977 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.135339 |
| PEG10 | paternally expressed 10 | -0.114714 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0997574 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0978076 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0877588 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0823624 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0765549 |
| CADM2 | cell adhesion molecule 2 | -0.0717232 |
| NDRG1 | N-myc downstream regulated 1 | -0.0669361 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0657209 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0654246 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0650002 |
| TMSB10 | thymosin beta 10 | -0.0612777 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0576035 |
| MEOX2 | mesenchyme homeobox 2 | -0.0539394 |
| FTL | ferritin, light polypeptide | -0.0535769 |
| COL1A2 | collagen, type I, alpha 2 | -0.0510374 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0509894 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0495027 |
| PKM | pyruvate kinase, muscle | -0.0491516 |
| RPS25 | ribosomal protein S25 | -0.0489709 |
| RPL35A | ribosomal protein L35a | -0.0487708 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0482763 |
| VIM | vimentin | -0.0473949 |
| RPLP1 | ribosomal protein, large, P1 | -0.0444098 |
| NFIB | nuclear factor I/B | -0.0436691 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0425456 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0408383 |
| FN1 | fibronectin 1 | -0.04077 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0382506 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0378719 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0376918 |
| TPM4 | tropomyosin 4 | -0.0369165 |
| HMGA2 | high mobility group AT-hook 2 | -0.0355204 |
| TULP4 | tubby like protein 4 | -0.0352595 |
| TUBB | tubulin, beta class I | -0.0350639 |
| CANX | calnexin | -0.0350325 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0342305 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0339643 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.033912 |
| IER3 | immediate early response 3 | -0.0335061 |
| AK1 | adenylate kinase 1 | -0.0330341 |
| BSG | basigin (Ok blood group) | -0.0315445 |
| CALR | calreticulin | -0.0315218 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0313337 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0306478 |
| FBXO11 | F-box protein 11 | -0.0305654 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0304779 |
| NFIA | nuclear factor I/A | -0.0304197 |
| S100A10 | S100 calcium binding protein A10 | -0.030291 |
| PDGFC | platelet derived growth factor C | -0.0302087 |
| SBF2 | SET binding factor 2 | -0.0297058 |
| ERBIN | erbb2 interacting protein | -0.0294659 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.029425 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0293398 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0292486 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0289977 |
| RPS5 | ribosomal protein S5 | -0.0286886 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0286314 |
| DENND1A | DENN/MADD domain containing 1A | -0.0285427 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0284428 |
| RPS20 | ribosomal protein S20 | -0.0283102 |
| ACTG1 | actin gamma 1 | -0.0281843 |
| HBP1 | HMG-box transcription factor 1 | -0.027794 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0276855 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0275224 |
| RPL28 | ribosomal protein L28 | -0.0273623 |
| RHEB | Ras homolog enriched in brain | -0.0272984 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0270691 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0270597 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0268847 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0268102 |
| RPL31 | ribosomal protein L31 | -0.0267925 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0266923 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0266624 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0266022 |
| ANXA2 | annexin A2 | -0.0265472 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0264488 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0262167 |
| NUP153 | nucleoporin 153kDa | -0.0260364 |
| TRIM24 | tripartite motif containing 24 | -0.0259045 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0256755 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0256631 |
| DTNA | dystrobrevin, alpha | -0.0256043 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0254769 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0254661 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0254297 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0253865 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0252056 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0250242 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0249793 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0249084 |
| COG5 | component of oligomeric golgi complex 5 | -0.0248911 |
| TMEM123 | transmembrane protein 123 | -0.0246959 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0244314 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0243763 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0243329 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0242516 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0241576 |
